arl13a ADP-ribosylation factor-like 13A [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: arl13aprovided by ZNC
Official Full Name: ADP-ribosylation factor-like 13Aprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1790
See related: Ensembl:ENSDARG00000052575 AllianceGenome:ZFIN:ZDB-GENE-040426-1790
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:73398
Summary: Predicted to enable GTP binding activity. Predicted to be involved in non-motile cilium assembly and receptor localization to non-motile cilium. Predicted to be active in ciliary membrane and non-motile cilium. Is expressed in liver; mandibular arch skeleton; nervous system; and pronephros. Orthologous to human ARL13A (ADP ribosylation factor like GTPase 13A). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 14

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	14	NC_007125.7 (41293110..41308556, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	14	NC_007125.6 (40925855..40941302, complement)

Chromosome 14 - NC_007125.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Between 2 and 5 days post fertilization (dpf), arl13b is expressed in neural tissues while expression of arl13a is downregulated by 2 dpf and restricted to craniofacial structures. These results indicate that arl13a and arl13b have evolved different roles and that arl13a does not function in the zebrafish retina.
Title: Developmental expression of the zebrafish Arf-like small GTPase paralogs arl13a and arl13b.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables GTP binding	IEA Inferred from Electronic Annotation more info
enables GTPase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in non-motile cilium assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in receptor localization to non-motile cilium	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in ciliary membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in non-motile cilium	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ADP-ribosylation factor-like protein 13A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200818.1 → NP_957112.1 ADP-ribosylation factor-like protein 13A

See identical proteins and their annotated locations for NP_957112.1

Status: PROVISIONAL

Source sequence(s)

BC059702

UniProtKB/TrEMBL

Q6PBH9

Conserved Domains (1) summary

cd04161
Location:23 → 189

Arl2l1_Arl13_like; Arl2-like protein 1 (Arl2l1) and Arl13

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007125.7 Reference GRCz11 Primary Assembly

Range

41293110..41308556 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_021481069.1 → XP_021336744.1 ADP-ribosylation factor-like protein 13A isoform X2

UniProtKB/TrEMBL

A0A8M9QGH9

Conserved Domains (1) summary

cd04161
Location:48 → 214

Arl2l1_Arl13_like; Arl2-like protein 1 (Arl2l1) and Arl13
XM_005173309.3 → XP_005173366.1 ADP-ribosylation factor-like protein 13A isoform X1

UniProtKB/TrEMBL

A0A8M2BKM6, F1QKW5

Related

ENSDARP00000120899.1, ENSDART00000138232.2

Conserved Domains (1) summary

cd04161
Location:48 → 214

Arl2l1_Arl13_like; Arl2-like protein 1 (Arl2l1) and Arl13