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    blos-1 Biogenesis of lysosome-related organelles complex 1 subunit 1 [ Caenorhabditis elegans ]

    Gene ID: 176435, updated on 12-Jun-2024

    Summary

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    Gene symbol
    blos-1
    Gene description
    Biogenesis of lysosome-related organelles complex 1 subunit 1
    Locus tag
    CELE_T20G5.10
    See related
    AllianceGenome:WB:WBGene00011872
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in endosomal transport. Predicted to be located in cytosol; mitochondrial intermembrane space; and mitochondrial matrix. Predicted to be part of BLOC-1 complex. Is expressed in excretory cell; intestine; and nervous system. Orthologous to human BLOC1S1 (biogenesis of lysosomal organelles complex 1 subunit 1). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See blos-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003281.10 (10211002..10211946, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene protein of unknown function DB domain-containing protein Neighboring gene ncRNA Neighboring gene putative clathrin heavy chain 1 Neighboring gene Partner of Y14 and mago Neighboring gene Bestrophin homolog;Bestrophin homolog 18 Neighboring gene putative citrate synthase, mitochondrial Neighboring gene DRBM domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Complementary RNA amplification methods enhance microarray identification of transcripts expressed in the C. elegans nervous system. Watson JD, et al. BMC Genomics, 2008 Feb 19. PMID 18284693, Free PMC Article
    2. C. elegans BLOC-1 functions in trafficking to lysosome-related gut granules. Hermann GJ, et al. PLoS One, 2012. PMID 22916203, Free PMC Article
    3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endosomal transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endosomal transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in localization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of BLOC-1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of BLOC-1 complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of BLOC-1 complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial intermembrane space IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Biogenesis of lysosome-related organelles complex 1 subunit 1
    NP_499262.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      10211002..10211946 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066861.5 → NP_499262.2  Biogenesis of lysosome-related organelles complex 1 subunit 1 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q22616
    Nucleotide Protein
    Heading Accession and Version

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