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    C8orf76 chromosome 8 open reading frame 76 [ Homo sapiens (human) ]

    Gene ID: 84933, updated on 5-Mar-2024

    Summary

    Official Symbol
    C8orf76provided by HGNC
    Official Full Name
    chromosome 8 open reading frame 76provided by HGNC
    Primary source
    HGNC:HGNC:25924
    See related
    Ensembl:ENSG00000189376 AllianceGenome:HGNC:25924
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Ubiquitous expression in colon (RPKM 8.2), lymph node (RPKM 8.0) and 25 other tissues See more
    Orthologs
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    Genomic context

    See C8orf76 in Genome Data Viewer
    Location:
    8q24.13
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (123219967..123241377, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (124351104..124372514, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (124232207..124253617, complement)

    Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 83 member A Neighboring gene FAM83A antisense RNA 1 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr8:124219477-124220229 Neighboring gene microRNA 4663 Neighboring gene ZHX1-C8orf76 readthrough Neighboring gene H3K27ac hESC enhancer GRCh37_chr8:124253403-124253903 Neighboring gene ubiquitin A-52 residue ribosomal protein fusion product 1 pseudogene 5 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 27870 Neighboring gene zinc fingers and homeoboxes 1 Neighboring gene tRNA-Phe (anticodon GAA) 12-1 Neighboring gene RNA, U6 small nuclear 628, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    uncharacterized protein C8orf76

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_032847.3NP_116236.1  uncharacterized protein C8orf76

      See identical proteins and their annotated locations for NP_116236.1

      Status: VALIDATED

      Source sequence(s)
      BC067796, DR156993
      Consensus CDS
      CCDS6341.1
      UniProtKB/Swiss-Prot
      Q53HC1, Q96K31
      Related
      ENSP00000276704.4, ENST00000276704.6
      Conserved Domains (2) summary
      TIGR03939
      Location:64199
      PGA_TPR_OMP; poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA
      sd00006
      Location:130159
      TPR; TPR repeat [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

      Range
      123219967..123241377 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060932.1 Alternate T2T-CHM13v2.0

      Range
      124351104..124372514 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)