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    NF-YA2 nuclear factor Y, subunit A2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819738, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NF-YA2
    Official Full Name
    nuclear factor Y, subunit A2
    Primary source
    TAIR:AT3G05690
    Locus tag
    AT3G05690
    See related
    Araport:AT3G05690
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ''nuclear factor Y; ATHAP2B; AtNF-YA2; F18C1.4; F18C1_4; HAP2B; HEME ACTIVATOR PROTEIN (YEAST) HOMOLOG 2B; nuclear factor Y; subunit A2; subunit A2''; UNE8; UNFERTILIZED EMBRYO SAC 8
    Summary
    Encodes a subunit of CCAAT-binding complex, binds to CCAAT box motif present in some plant promoter sequences. One of three members of this class (HAP2A, HAP2B, HAP2C), it is expressed in vegetative and reproductive tissues.
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    Genomic context

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    See NF-YA2 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (1676504..1679061, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene embryo defective 2016 Neighboring gene Cystatin/monellin superfamily protein Neighboring gene Drought-responsive family protein Neighboring gene ncRNA Neighboring gene syntaxin of plants 43 Neighboring gene importin alpha isoform 7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Transcription factors NF-YA2 and NF-YA10 regulate leaf growth via auxin signaling in Arabidopsis. Zhang M, et al. Sci Rep, 2017 May 3. PMID 28469131, Free PMC Article
    2. Stress-induced early flowering is mediated by miR169 in Arabidopsis thaliana. Xu MY, et al. J Exp Bot, 2014 Jan. PMID 24336445
    3. A miR169 isoform regulates specific NF-YA targets and root architecture in Arabidopsis. Sorin C, et al. New Phytol, 2014 Jun. PMID 24533947
    4. Multiple genes encoding the conserved CCAAT-box transcription factor complex are expressed in Arabidopsis. Edwards D, et al. Plant Physiol, 1998 Jul. PMID 9662544, Free PMC Article
    5. Arabidopsis DPB3-1, a DREB2A interactor, specifically enhances heat stress-induced gene expression by forming a heat stress-specific transcriptional complex with NF-Y subunits. Sato H, et al. Plant Cell, 2014 Dec. PMID 25490919, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Findings showed leaf development was regulated by NF-YA2 and NF-YA10 through the auxin-signaling pathway and may provide a new insight into the genetic engineering of vegetables biomass and crop productivity.
      Title: Transcription factors NF-YA2 and NF-YA10 regulate leaf growth via auxin signaling in Arabidopsis.
    2. The authors identified a regulatory node involving the particular miR169defg isoform and NF-YA2 and NF-YA10 genes that acts in the control of primary root growth.
      Title: A miR169 isoform regulates specific NF-YA targets and root architecture in Arabidopsis.
    3. The miR169 family regulates stress-induced flowering by repressing the AtNF-YA transcription factor, which in turn reduces the expression of FLOWERING LOCUS C (FLC), allowing for the expression of FLC target genes
      Title: Stress-induced early flowering is mediated by miR169 in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_111443.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within double fertilization forming a zygote and endosperm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    involved_in response to heat IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of CCAAT-binding factor complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    nuclear factor Y, subunit A2
    NP_187220.1
    • ''nuclear factor Y, subunit A2'' (NF-YA2); CONTAINS InterPro DOMAIN/s: CCAAT-binding transcription factor, subunit B (InterPro:IPR001289); BEST Arabidopsis thaliana protein match is: nuclear factor Y, subunit A10 (TAIR:AT5G06510.2); Has 655 Blast hits to 655 proteins in 159 species: Archae - 0; Bacteria - 0; Metazoa - 138; Fungi - 132; Plants - 359; Viruses - 0; Other Eukaryotes - 26 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      1676504..1679061 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001337602.1 → NP_001327635.1  nuclear factor Y, subunit A2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178VK23, A0A1I9LSX7, A0A5S9XA32, Q0WS51

    2. NM_111443.4 → NP_187220.1  nuclear factor Y, subunit A2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187220.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23631, Q9M9X4
      UniProtKB/TrEMBL
      A0A178VK23, A0A5S9XA32, A0A654F9Q6, Q0WS51, Q147N1
      Conserved Domains (1) summary
      smart00521
      Location:133 → 198
      CBF; CCAAT-Binding transcription Factor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M9X4.1

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