Format

Send to:

Choose Destination
    • Showing Current items.

    Sun1 Sad1 and UNC84 domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 77053, updated on 16-Aug-2021

    Summary

    Official Symbol
    Sun1provided by MGI
    Official Full Name
    Sad1 and UNC84 domain containing 1provided by MGI
    Primary source
    MGI:MGI:1924303
    See related
    Ensembl:ENSMUSG00000036817
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Unc8; Unc84a; mKIAA0810; 4632417G13Rik; 5730434D03Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 24.4), bladder adult (RPKM 22.9) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Sun1 in Genome Data Viewer
    Location:
    5; 5 G2
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (139186313..139235594)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (139200564..139249839)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (139676624..139725749)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene platelet derived growth factor, alpha Neighboring gene protein kinase, cAMP dependent regulatory, type I beta Neighboring gene dynein, axonemal assembly factor 5 Neighboring gene golgi to ER traffic protein 4 Neighboring gene ArfGAP with dual PH domains 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA0810

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cytoskeleton-nuclear membrane anchor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables lamin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein-membrane adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in acrosomal membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in integral component of membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in integral component of nuclear inner membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    part_of meiotic nuclear membrane microtubule tethering complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of meiotic nuclear membrane microtubule tethering complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nuclear envelope IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nuclear envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    colocalizes_with nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear envelope TAS
    Traceable Author Statement
    more info
     
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    NOT located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    SUN domain-containing protein 1
    Names
    protein unc-84 homolog A
    sad1/unc-84 protein-like 1
    unc-84 homolog A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001256115.1NP_001243044.1  SUN domain-containing protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001243044.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AK036187, AV239459, CK389844
      Consensus CDS
      CCDS57395.1
      UniProtKB/Swiss-Prot
      Q9D666
      Related
      ENSMUSP00000106508.3, ENSMUST00000110884.9
      Conserved Domains (2) summary
      pfam07738
      Location:740874
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:73378
      MRP; Mitochondrial RNA binding protein MRP
    2. NM_001256116.2NP_001243045.1  SUN domain-containing protein 1 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (3) is shorter than isoform 1.
      Source sequence(s)
      AC125065
      Consensus CDS
      CCDS57396.1
      UniProtKB/Swiss-Prot
      Q9D666
      Related
      ENSMUSP00000077756.7, ENSMUST00000078690.13
      Conserved Domains (2) summary
      pfam07738
      Location:713847
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:73351
      MRP; Mitochondrial RNA binding protein MRP
    3. NM_001256117.1NP_001243046.1  SUN domain-containing protein 1 isoform 4

      See identical proteins and their annotated locations for NP_001243046.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks three consecutive exons in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (4) lacks an internal segment, compared to isoform 1.
      Source sequence(s)
      AK014585, AV239459, CK389844
      Consensus CDS
      CCDS57397.1
      UniProtKB/Swiss-Prot
      Q9D666
      Related
      ENSMUSP00000106507.3, ENSMUST00000110883.9
      Conserved Domains (2) summary
      pfam07738
      Location:654788
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:73292
      MRP; Mitochondrial RNA binding protein MRP
    4. NM_001256118.1NP_001243047.1  SUN domain-containing protein 1 isoform 5

      See identical proteins and their annotated locations for NP_001243047.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) lacks four consecutive exons in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (5) lacks an internal segment, compared to isoform 1.
      Source sequence(s)
      AK160281, BQ551727, HQ402597
      Consensus CDS
      CCDS57398.1
      UniProtKB/Swiss-Prot
      Q9D666
      Related
      ENSMUSP00000106506.2, ENSMUST00000110882.8
      Conserved Domains (2) summary
      pfam07738
      Location:621755
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:73259
      MRP; Mitochondrial RNA binding protein MRP
    5. NM_001359494.1NP_001346423.1  SUN domain-containing protein 1 isoform 6

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) lacks an in-frame exon in the coding region and uses an alternate in-frame splice junction, compared to variant 1. The resulting isoform (6) is shorter than isoform 1.
      Source sequence(s)
      AC125065
      Conserved Domains (3) summary
      pfam07738
      Location:712846
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:73351
      MRP; Mitochondrial RNA binding protein MRP
      cl25732
      Location:428579
      SMC_N; RecF/RecN/SMC N terminal domain
    6. NM_001359496.1NP_001346425.1  SUN domain-containing protein 1 isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) lacks two alternate in-frame exons, compared to variant 1. The resulting isoform (7) is shorter than isoform 1.
      Source sequence(s)
      AC125065
      Conserved Domains (3) summary
      pfam07738
      Location:676810
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:73314
      MRP; Mitochondrial RNA binding protein MRP
      cl25732
      Location:385564
      SMC_N; RecF/RecN/SMC N terminal domain
    7. NM_024451.2NP_077771.1  SUN domain-containing protein 1 isoform 1

      See identical proteins and their annotated locations for NP_077771.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) is the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AK160281, AK167686, BY036585
      Consensus CDS
      CCDS19804.1
      UniProtKB/Swiss-Prot
      Q9D666
      Related
      ENSMUSP00000056655.8, ENSMUST00000058716.14
      Conserved Domains (5) summary
      COG1196
      Location:486665
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam07738
      Location:777911
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:63415
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:709734
      Sun2_CC2; SUN2 coiled coil domain 2
      cd21439
      Location:553606
      SUN1_cc1; coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      139186313..139235594
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036165598.1XP_036021491.1  SUN domain-containing protein 1 isoform X22

      Related
      ENSMUSP00000098086.4, ENSMUST00000100517.10
      Conserved Domains (1) summary
      pfam09387
      Location:92253
      MRP; Mitochondrial RNA binding protein MRP
    2. XM_017321156.3XP_017176645.1  SUN domain-containing protein 1 isoform X1

      Conserved Domains (4) summary
      pfam07738
      Location:815949
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:543706
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:102259
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:747772
      Sun2_CC2; SUN2 coiled coil domain 2
    3. XM_017321157.3XP_017176646.1  SUN domain-containing protein 1 isoform X2

      Conserved Domains (4) summary
      pfam07738
      Location:814948
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:543705
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:102259
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:746771
      Sun2_CC2; SUN2 coiled coil domain 2
    4. XM_036165596.1XP_036021489.1  SUN domain-containing protein 1 isoform X8

      Conserved Domains (4) summary
      pfam07738
      Location:777911
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:92416
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:709734
      Sun2_CC2; SUN2 coiled coil domain 2
      cd21439
      Location:554605
      SUN1_cc1; coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins
    5. XM_017321162.3XP_017176651.1  SUN domain-containing protein 1 isoform X6

      Conserved Domains (4) summary
      pfam07738
      Location:778912
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:506669
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:102416
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:710735
      Sun2_CC2; SUN2 coiled coil domain 2
    6. XM_017321164.3XP_017176653.1  SUN domain-containing protein 1 isoform X10

      Conserved Domains (4) summary
      pfam07738
      Location:756890
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:484647
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:102394
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:688713
      Sun2_CC2; SUN2 coiled coil domain 2
    7. XM_030254889.2XP_030110749.1  SUN domain-containing protein 1 isoform X3

      Conserved Domains (4) summary
      pfam07738
      Location:805939
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:534696
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:102250
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:737762
      Sun2_CC2; SUN2 coiled coil domain 2
    8. XM_017321165.3XP_017176654.1  SUN domain-containing protein 1 isoform X11

      Conserved Domains (4) summary
      pfam07738
      Location:751885
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:479642
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:102389
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:683708
      Sun2_CC2; SUN2 coiled coil domain 2
    9. XM_017321168.3XP_017176657.1  SUN domain-containing protein 1 isoform X13

      Conserved Domains (4) summary
      pfam07738
      Location:714848
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:442605
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:102352
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:646671
      Sun2_CC2; SUN2 coiled coil domain 2
    10. XM_017321163.3XP_017176652.1  SUN domain-containing protein 1 isoform X9

      Conserved Domains (4) summary
      pfam07738
      Location:768902
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:497659
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:102407
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:700725
      Sun2_CC2; SUN2 coiled coil domain 2
    11. XM_030254894.2XP_030110754.1  SUN domain-containing protein 1 isoform X16

      Conserved Domains (4) summary
      pfam07738
      Location:691825
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:420582
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:102330
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:623648
      Sun2_CC2; SUN2 coiled coil domain 2
    12. XM_030254890.2XP_030110750.1  SUN domain-containing protein 1 isoform X12

      Conserved Domains (4) summary
      pfam07738
      Location:747881
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:475638
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:102385
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:679704
      Sun2_CC2; SUN2 coiled coil domain 2
    13. XM_017321170.3XP_017176659.1  SUN domain-containing protein 1 isoform X15

      Conserved Domains (4) summary
      pfam07738
      Location:692826
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:420583
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:102330
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:624649
      Sun2_CC2; SUN2 coiled coil domain 2
    14. XM_017321171.3XP_017176660.1  SUN domain-containing protein 1 isoform X18

      Conserved Domains (4) summary
      pfam07738
      Location:659793
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:387550
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:102297
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:591616
      Sun2_CC2; SUN2 coiled coil domain 2
    15. XM_017321169.3XP_017176658.1  SUN domain-containing protein 1 isoform X14

      Conserved Domains (4) summary
      pfam07738
      Location:704838
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:433595
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:102343
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:636661
      Sun2_CC2; SUN2 coiled coil domain 2
    16. XM_036165597.1XP_036021490.1  SUN domain-containing protein 1 isoform X17

      Conserved Domains (4) summary
      pfam07738
      Location:682816
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:92321
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:614639
      Sun2_CC2; SUN2 coiled coil domain 2
      cd21439
      Location:459510
      SUN1_cc1; coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins
    17. XM_006504767.4XP_006504830.1  SUN domain-containing protein 1 isoform X19

      Conserved Domains (4) summary
      pfam07738
      Location:650784
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:378541
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:102288
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:582607
      Sun2_CC2; SUN2 coiled coil domain 2
    18. XM_036165595.1XP_036021488.1  SUN domain-containing protein 1 isoform X7

      Conserved Domains (5) summary
      COG1196
      Location:486665
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam07738
      Location:777911
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:63415
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:709734
      Sun2_CC2; SUN2 coiled coil domain 2
      cd21439
      Location:553606
      SUN1_cc1; coiled-coil domain 1 of SUN domain-containing protein 1 and similar proteins
    19. XM_017321160.2XP_017176649.1  SUN domain-containing protein 1 isoform X5

      Conserved Domains (4) summary
      pfam07738
      Location:786920
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:514677
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:73230
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:718743
      Sun2_CC2; SUN2 coiled coil domain 2
    20. XM_017321159.2XP_017176648.1  SUN domain-containing protein 1 isoform X5

      Conserved Domains (4) summary
      pfam07738
      Location:786920
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:514677
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:73230
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:718743
      Sun2_CC2; SUN2 coiled coil domain 2
    21. XM_017321161.2XP_017176650.1  SUN domain-containing protein 1 isoform X5

      Conserved Domains (4) summary
      pfam07738
      Location:786920
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:514677
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:73230
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:718743
      Sun2_CC2; SUN2 coiled coil domain 2
    22. XM_030254895.2XP_030110755.1  SUN domain-containing protein 1 isoform X20

      Conserved Domains (4) summary
      pfam07738
      Location:629763
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:358520
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:82268
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:561586
      Sun2_CC2; SUN2 coiled coil domain 2
    23. XM_030254897.2XP_030110757.1  SUN domain-containing protein 1 isoform X21

      Conserved Domains (4) summary
      pfam07738
      Location:620754
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:349511
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:73259
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:552577
      Sun2_CC2; SUN2 coiled coil domain 2
    24. XM_017321158.1XP_017176647.1  SUN domain-containing protein 1 isoform X4

      Conserved Domains (4) summary
      pfam07738
      Location:795929
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam07888
      Location:523686
      CALCOCO1; Calcium binding and coiled-coil domain (CALCOCO1) like
      pfam09387
      Location:82239
      MRP; Mitochondrial RNA binding protein MRP
      pfam18580
      Location:727752
      Sun2_CC2; SUN2 coiled coil domain 2
    Support Center