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    Sun1 Sad1 and UNC84 domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 77053, updated on 5-Aug-2018

    Summary

    Official Symbol
    Sun1provided by MGI
    Official Full Name
    Sad1 and UNC84 domain containing 1provided by MGI
    Primary source
    MGI:MGI:1924303
    See related
    Ensembl:ENSMUSG00000036817 Vega:OTTMUSG00000025175
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Unc84a; mKIAA0810; 4632417G13Rik; 5730434D03Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 24.4), bladder adult (RPKM 22.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Sun1 in Genome Data Viewer
    Location:
    5; 5 G2
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (139200556..139249839)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (139676624..139725749)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene platelet derived growth factor, alpha Neighboring gene protein kinase, cAMP dependent regulatory, type I beta Neighboring gene dynein, axonemal assembly factor 5 Neighboring gene golgi to ER traffic protein 4 Neighboring gene ArfGAP with dual PH domains 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA0810

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    lamin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein membrane anchor IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    centrosome localization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cytoskeletal anchoring at nuclear membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoskeletal anchoring at nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    meiotic attachment of telomere to nuclear envelope IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear envelope organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear envelope organization ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear matrix anchoring at nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    synapsis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    acrosomal membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cell ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    integral component of nuclear inner membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    meiotic nuclear membrane microtubule tethering complex ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear envelope IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    NOT nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    SUN domain-containing protein 1
    Names
    protein unc-84 homolog A
    sad1/unc-84 protein-like 1
    unc-84 homolog A

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001256115.1NP_001243044.1  SUN domain-containing protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001243044.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AK036187, AV239459, CK389844
      Consensus CDS
      CCDS57395.1
      UniProtKB/Swiss-Prot
      Q9D666
      Related
      ENSMUSP00000106508.2, OTTMUSP00000030478, ENSMUST00000110884.8, OTTMUST00000061945
      Conserved Domains (2) summary
      pfam07738
      Location:740874
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:73378
      MRP; Mitochondrial RNA binding protein MRP
    2. NM_001256116.2NP_001243045.1  SUN domain-containing protein 1 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an in-frame exon in the coding region, compared to variant 1. The resulting isoform (3) is shorter than isoform 1.
      Source sequence(s)
      AC125065
      Consensus CDS
      CCDS57396.1
      UniProtKB/Swiss-Prot
      Q9D666
      Related
      ENSMUSP00000077756.6, OTTMUSP00000030479, ENSMUST00000078690.12
      Conserved Domains (2) summary
      pfam07738
      Location:713847
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:73351
      MRP; Mitochondrial RNA binding protein MRP
    3. NM_001256117.1NP_001243046.1  SUN domain-containing protein 1 isoform 4

      See identical proteins and their annotated locations for NP_001243046.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks three consecutive exons in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (4) lacks an internal segment, compared to isoform 1.
      Source sequence(s)
      AK014585, AV239459, CK389844
      Consensus CDS
      CCDS57397.1
      UniProtKB/Swiss-Prot
      Q9D666
      Related
      ENSMUSP00000106507.2, OTTMUSP00000030477, ENSMUST00000110883.8, OTTMUST00000061944
      Conserved Domains (2) summary
      pfam07738
      Location:654788
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:73292
      MRP; Mitochondrial RNA binding protein MRP
    4. NM_001256118.1NP_001243047.1  SUN domain-containing protein 1 isoform 5

      See identical proteins and their annotated locations for NP_001243047.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) lacks four consecutive exons in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (5) lacks an internal segment, compared to isoform 1.
      Source sequence(s)
      AK160281, BQ551727, HQ402597
      Consensus CDS
      CCDS57398.1
      UniProtKB/Swiss-Prot
      Q9D666
      Related
      ENSMUSP00000106506.1, OTTMUSP00000030480, ENSMUST00000110882.7, OTTMUST00000061947
      Conserved Domains (2) summary
      pfam07738
      Location:621755
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:73259
      MRP; Mitochondrial RNA binding protein MRP
    5. NM_001359494.1NP_001346423.1  SUN domain-containing protein 1 isoform 6

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) lacks an in-frame exon in the coding region and uses an alternate in-frame splice junction, compared to variant 1. The resulting isoform (6) is shorter than isoform 1.
      Source sequence(s)
      AC125065
      Conserved Domains (3) summary
      pfam07738
      Location:712846
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:73351
      MRP; Mitochondrial RNA binding protein MRP
      cl25732
      Location:428579
      SMC_N; RecF/RecN/SMC N terminal domain
    6. NM_001359496.1NP_001346425.1  SUN domain-containing protein 1 isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) lacks two alternate in-frame exons, compared to variant 1. The resulting isoform (7) is shorter than isoform 1.
      Source sequence(s)
      AC125065
      Conserved Domains (3) summary
      pfam07738
      Location:676810
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:73314
      MRP; Mitochondrial RNA binding protein MRP
      cl25732
      Location:385564
      SMC_N; RecF/RecN/SMC N terminal domain
    7. NM_024451.2NP_077771.1  SUN domain-containing protein 1 isoform 1

      See identical proteins and their annotated locations for NP_077771.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) is the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AK160281, AK167686, BY036585
      Consensus CDS
      CCDS19804.1
      UniProtKB/Swiss-Prot
      Q9D666
      Related
      ENSMUSP00000056655.7, OTTMUSP00000030476, ENSMUST00000058716.13, OTTMUST00000061943
      Conserved Domains (2) summary
      pfam07738
      Location:777911
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:73224
      MRP; Mitochondrial RNA binding protein MRP

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      139200556..139249839
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017321156.1XP_017176645.1  SUN domain-containing protein 1 isoform X1

    2. XM_017321157.1XP_017176646.1  SUN domain-containing protein 1 isoform X2

    3. XM_017321162.1XP_017176651.1  SUN domain-containing protein 1 isoform X6

    4. XM_017321164.1XP_017176653.1  SUN domain-containing protein 1 isoform X9

    5. XM_006504758.2XP_006504821.1  SUN domain-containing protein 1 isoform X3

      Conserved Domains (2) summary
      pfam07738
      Location:806940
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:102253
      MRP; Mitochondrial RNA binding protein MRP
    6. XM_017321165.1XP_017176654.1  SUN domain-containing protein 1 isoform X10

    7. XM_006504762.2XP_006504825.1  SUN domain-containing protein 1 isoform X7

      Conserved Domains (2) summary
      pfam07738
      Location:769903
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:102407
      MRP; Mitochondrial RNA binding protein MRP
    8. XM_017321163.1XP_017176652.1  SUN domain-containing protein 1 isoform X8

    9. XM_017321168.1XP_017176657.1  SUN domain-containing protein 1 isoform X14

    10. XM_017321170.1XP_017176659.1  SUN domain-containing protein 1 isoform X17

    11. XM_017321171.1XP_017176660.1  SUN domain-containing protein 1 isoform X19

    12. XM_006504764.2XP_006504827.1  SUN domain-containing protein 1 isoform X11

    13. XM_017321166.1XP_017176655.1  SUN domain-containing protein 1 isoform X12

    14. XM_017321169.1XP_017176658.1  SUN domain-containing protein 1 isoform X16

    15. XM_006504765.1XP_006504828.1  SUN domain-containing protein 1 isoform X15

    16. XM_006504766.2XP_006504829.1  SUN domain-containing protein 1 isoform X18

      Conserved Domains (2) summary
      pfam07738
      Location:683817
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:102321
      MRP; Mitochondrial RNA binding protein MRP
    17. XM_006504767.2XP_006504830.1  SUN domain-containing protein 1 isoform X20

      Conserved Domains (2) summary
      pfam07738
      Location:650784
      Sad1_UNC; Sad1 / UNC-like C-terminal
      pfam09387
      Location:102288
      MRP; Mitochondrial RNA binding protein MRP
    18. XM_017321159.1XP_017176648.1  SUN domain-containing protein 1 isoform X5

    19. XM_017321160.1XP_017176649.1  SUN domain-containing protein 1 isoform X5

    20. XM_017321161.1XP_017176650.1  SUN domain-containing protein 1 isoform X5

    21. XM_017321158.1XP_017176647.1  SUN domain-containing protein 1 isoform X4

    22. XM_017321167.1XP_017176656.1  SUN domain-containing protein 1 isoform X13

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