NLRP5 NLR family pyrin domain containing 5 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: NLRP5provided by VGNC
Official Full Name: NLR family pyrin domain containing 5provided by VGNC
Primary source: VGNC:VGNC:112006
See related: Ensembl:ENSMMUG00000028710
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Also known as: MATER
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 19

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	19	NC_041772.1 (55755904..55850895)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	19	NC_027911.1 (53071682..53129325, complement)

Chromosome 19 - NC_041772.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cell cortex	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in mitochondrion	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed
part_of subcortical maternal complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: NACHT, LRR and PYD domains-containing protein 5

Names: NACHT, LRR and PYD containing protein 5; maternal antigen that embryos require

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001127631.1 → NP_001121103.1 NACHT, LRR and PYD domains-containing protein 5

See identical proteins and their annotated locations for NP_001121103.1

Status: PROVISIONAL

Source sequence(s)

EU340329

UniProtKB/TrEMBL

A0A1D5QYW1, B0FNB0

Conserved Domains (6) summary

cd00116
Location:867 → 1158

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

cd08320
Location:65 → 148

Pyrin_NALPs; Pyrin death domain found in NALP proteins

sd00033
Location:838 → 862

LRR_RI; leucine-rich repeat [structural motif]

sd00034
Location:924 → 951

LRR_AMN1; leucine-rich repeat [structural motif]

pfam05729
Location:279 → 442

NACHT; NACHT domain

cl00909
Location:145 → 227

Ribosomal_L24e_L24; Ribosomal protein L24e/L24 is a ribosomal protein found in eukaryotes (L24) and in archaea (L24e, distinct from archaeal L24). L24e/L24 is located on the surface of the large subunit, adjacent to proteins L14 and L3, and near the translation factor ...

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

NC_041772.1 Reference Mmul_10 Primary Assembly

Range

55755904..55850895

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_028838413.1 → XP_028694246.1 NACHT, LRR and PYD domains-containing protein 5 isoform X3

UniProtKB/TrEMBL

A0A1D5QYW1

Conserved Domains (6) summary

cd08320
Location:33 → 115

Pyrin_NALPs; Pyrin death domain found in NALP proteins

sd00033
Location:805 → 829

LRR_RI; leucine-rich repeat [structural motif]

sd00034
Location:891 → 918

LRR_AMN1; leucine-rich repeat [structural motif]

pfam05729
Location:246 → 409

NACHT; NACHT domain

pfam16001
Location:121 → 228

DUF4775; Domain of unknown function (DUF4775)

cl29113
Location:834 → 1125

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
XM_028838411.1 → XP_028694244.1 NACHT, LRR and PYD domains-containing protein 5 isoform X2

UniProtKB/TrEMBL

A0A1D5QYW1

Conserved Domains (6) summary

cd08320
Location:44 → 126

Pyrin_NALPs; Pyrin death domain found in NALP proteins

sd00033
Location:816 → 840

LRR_RI; leucine-rich repeat [structural motif]

sd00034
Location:902 → 929

LRR_AMN1; leucine-rich repeat [structural motif]

pfam05729
Location:257 → 420

NACHT; NACHT domain

pfam16001
Location:132 → 239

DUF4775; Domain of unknown function (DUF4775)

cl29113
Location:845 → 1136

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
XM_015124964.2 → XP_014980450.2 NACHT, LRR and PYD domains-containing protein 5 isoform X1

UniProtKB/TrEMBL

A0A1D5QYW1

Related

ENSMMUP00000079416.1, ENSMMUT00000107103.1

Conserved Domains (6) summary

cd08320
Location:79 → 161

Pyrin_NALPs; Pyrin death domain found in NALP proteins

sd00033
Location:851 → 875

LRR_RI; leucine-rich repeat [structural motif]

sd00034
Location:937 → 964

LRR_AMN1; leucine-rich repeat [structural motif]

pfam05729
Location:292 → 455

NACHT; NACHT domain

pfam16001
Location:167 → 274

DUF4775; Domain of unknown function (DUF4775)

cl29113
Location:880 → 1171

LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...