Format

Send to:

Choose Destination
    • Showing Current items.

    Pcgf1 polycomb group ring finger 1 [ Mus musculus (house mouse) ]

    Gene ID: 69837, updated on 5-Sep-2021

    Summary

    Official Symbol
    Pcgf1provided by MGI
    Official Full Name
    polycomb group ring finger 1provided by MGI
    Primary source
    MGI:MGI:1917087
    See related
    Ensembl:ENSMUSG00000069678
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ns; Nspc1; AU024121; 2010002K04Rik
    Expression
    Ubiquitous expression in CNS E14 (RPKM 15.0), testis adult (RPKM 12.7) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Pcgf1 in Genome Data Viewer
    Location:
    6 C3; 6 35.94 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (83054173..83057836)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (83077552..83080855)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (83028384..83030849)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene DEAQ RNA-dependent ATPase Neighboring gene T cell leukemia, homeobox 2 Neighboring gene ladybird homeobox 2 Neighboring gene microRNA 3470a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables promoter-specific chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein C-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in histone H2A monoubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in histone H2A-K119 monoubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in histone H2A-K119 monoubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of PRC1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of PcG protein complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of PcG protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    polycomb group RING finger protein 1
    Names
    RING finger protein 68
    nervous system Polycomb-1
    nervous system polycomb 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_197992.1NP_932109.1  polycomb group RING finger protein 1

      See identical proteins and their annotated locations for NP_932109.1

      Status: VALIDATED

      Source sequence(s)
      BC028560
      Consensus CDS
      CCDS20270.1
      UniProtKB/Swiss-Prot
      Q8R023
      UniProtKB/TrEMBL
      A0A0R4J141
      Related
      ENSMUSP00000090277.3, ENSMUST00000092614.9
      Conserved Domains (2) summary
      pfam00097
      Location:3573
      zf-C3HC4; Zinc finger, C3HC4 type (RING finger)
      pfam16207
      Location:165241
      RAWUL; RAWUL domain RING finger- and WD40-associated ubiquitin-like

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      83054173..83057836
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030255588.2XP_030111448.1  polycomb group RING finger protein 1 isoform X1

      Related
      ENSMUSP00000135291.2, ENSMUST00000177177.8
      Conserved Domains (1) summary
      cd17081
      Location:83170
      RAWUL_PCGF1; RING finger- and WD40-associated ubiquitin-like (RAWUL) domain found in polycomb group RING finger protein 1 (PCGF1) and similar proteins
    Support Center