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    Anln anillin, actin binding protein [ Mus musculus (house mouse) ]

    Gene ID: 68743, updated on 23-Jun-2021

    Summary

    Official Symbol
    Anlnprovided by MGI
    Official Full Name
    anillin, actin binding proteinprovided by MGI
    Primary source
    MGI:MGI:1920174
    See related
    Ensembl:ENSMUSG00000036777
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    S; C78101; Scraps; 1110037A17Rik; 2900037I21Rik
    Expression
    Broad expression in liver E14 (RPKM 8.2), CNS E11.5 (RPKM 7.1) and 18 other tissues See more
    Orthologs
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    Genomic context

    See Anln in Genome Data Viewer
    Location:
    9; 9 A3
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (22242510..22302132, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (22331214..22389211, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (22135658..22193650, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene high mobility group nucleosomal binding domain 2 pseudogene Neighboring gene 40S ribosomal protein S20 pseudogene Neighboring gene RIKEN cDNA 9530077C05 gene Neighboring gene retinitis pigmentosa 9 (human) Neighboring gene ribosomal protein L7A pseudogene Neighboring gene Bardet-Biedl syndrome 9 (human)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in actomyosin contractile ring assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in glomerular visceral epithelial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within hematopoietic progenitor cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in mitotic cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within mitotic cytokinesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of bleb assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in septin ring organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in actomyosin contractile ring IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in actomyosin contractile ring ISO
    Inferred from Sequence Orthology
    more info
     
    located_in bleb ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell cortex region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in midbody ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    anillin
    Names
    actin-binding protein anillin
    anillin, actin binding protein (scraps homolog, Drosophila)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028390.3NP_082666.2  anillin

      See identical proteins and their annotated locations for NP_082666.2

      Status: VALIDATED

      Source sequence(s)
      AC093926, AK045703, AK046102, BM229484, CN458410
      Consensus CDS
      CCDS22927.1
      UniProtKB/Swiss-Prot
      Q8K298
      Related
      ENSMUSP00000045873.8, ENSMUST00000040912.9
      Conserved Domains (4) summary
      cd01263
      Location:9811107
      PH_anillin; Anillin Pleckstrin homology (PH) domain
      pfam00169
      Location:9841103
      PH; PH domain
      pfam08174
      Location:797950
      Anillin; Cell division protein anillin
      pfam16018
      Location:141227
      Anillin_N; Anillin N-terminus

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      22242510..22302132 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006510581.5XP_006510644.1  anillin isoform X1

      Conserved Domains (4) summary
      PHA03307
      Location:24206
      PHA03307; transcriptional regulator ICP4; Provisional
      cd01263
      Location:9991125
      PH_anillin; Anillin Pleckstrin homology (PH) domain
      pfam08174
      Location:797950
      Anillin; Cell division protein anillin
      pfam16018
      Location:141227
      Anillin_N; Anillin N-terminus
    2. XM_011242594.2XP_011240896.1  anillin isoform X3

      Conserved Domains (2) summary
      cd01263
      Location:504630
      PH_anillin; Anillin Pleckstrin homology (PH) domain
      pfam08174
      Location:302455
      Anillin; Cell division protein anillin
    3. XM_006510582.5XP_006510645.1  anillin isoform X2

      Conserved Domains (3) summary
      PHA03307
      Location:24206
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam08174
      Location:797950
      Anillin; Cell division protein anillin
      pfam16018
      Location:141227
      Anillin_N; Anillin N-terminus
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