Conserved Protein Domain Family
Anillin

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pfam08174: Anillin 
Cell division protein anillin
Anillin is a protein involved in septin organization during cell division. It is an actin binding protein that is localized to the cleavage furrow, and it maintains the localization of active myosin, which ensures the spatial control of concerted contraction during cytokinesis.
Statistics
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PSSM-Id: 285397
View PSSM: pfam08174
Aligned: 83 rows
Threshold Bit Score: 74.582
Threshold Setting Gi: 398405514
Created: 27-Jun-2015
Updated: 5-Aug-2015
Structure
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Aligned Rows:
PubMed ReferencesClick to see Conserved Features Help

pfam08174 is a member of the superfamily cl06980.
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160419246   94 CRGKIALSDIRIPLMWKDSDHFSNKECTq---------RF-----AI-----FC-----L---FRM-G--------A--- 134
gi 597587887 1128 fqrpSTFSRVFASPKKRKELEMKQKEEEq---------RV-----AQqnqrdAQ-----A---KRI-S--------V--- 1173
gi 399171340 1070 ktkTSTFSRVFASPKKRREMEQRQKDEEr---------QQ-----SE-----AL-----A---RQR-S--------R--- 1110
gi 780598171  199 rpkaSTFSRVFASPKKRKEMEQRMKEEDe---------RL-----AR-----EH-----LeaqAKI-Rn-------A--- 243
gi 154305844 1215 pskpSTFSRVFASPKKRKELEMRQKEEEq---------RIaqqkqQD-----AQ-----A---LKK-S--------S--- 1260
gi 258574221  989 pqkTSAFSRVFASPKKRREMELRQQMEAq---------Q------------------------LKQ-K--------T--- 1023
gi 528291843  984 ahkpSTFSRVFSSPKKRKELEARQREEEk---------MY-----AK-----MKeketrA---KKA-S--------H--- 1029
gi 154274163  353 shkTSTFSRVFASPKKRKELEQKQQLEAq---------Q------------------------LKQ-RkaeekalaE--- 395
gi 295660196 1102 FKGS-TFSRVFASPKKRKELEQRQQFEAq---------Q--------------------L---KQQ-K--------Tder 1139
gi 398405514 1144 GKT-SSLTRFLASPKKRAAEKERLEREAadaenrrrdeEE-----AR-----LQ-----Q---RKRqS--------A--- 1193
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 160419246  135 ---Q------VFDTDMV--IVDQT-------------V------------TDICFENVTIFneagpdfQIKIEVYS-CSA 177
gi 597587887 1174 ---I------PTAWDLLs-PLAAEdgsfgrsyvclkdH------------ESRCYGRPYV---------VDIACFNeWAT 1222
gi 399171340 1111 ---A------PSAYELLs-HLTADdgsfgrsyvclkeH------------EHRCFGRPY---------MAEIACFNeWAW 1159
gi 780598171  244 ---P------PTAYDLLs-PIVAEdgsfarsyvclkeH------------ESRCYGRPGI---------VEVACFNeWAT 292
gi 154305844 1261 ---Q------PTAWDLLs-PLAAAdgsfgrsyvclkdH------------ETRCFGRPYN---------VDVAAFNeWAT 1309
gi 258574221 1024 ---EekilagPDPWAKVr-NLVAKd------------GsfarayvclgdyEQHAFGRPLT---------VDVACFNeWAV 1078
gi 528291843 1030 ---Q------PTAWDLLs-PLAAEdgsfarsyvclkdH------------ESRCFGRPLT---------VEVPCFNeWAT 1078
gi 154274163  396 ---K------KNPLDALr-HLVASd------------GsfarayvslsdyEKAAFGRPLT---------VDVTCFNeWAT 444
gi 295660196 1140 aldK------ENPWNALr-PLVASd------------GsfarayvslsdyEKAAFGRPLT---------VDVTCFNeWAS 1191
gi 398405514 1194 ---H------PSAWDLLhtLVNPAdgsfarayvnlraH------------EKQCFGRPLVV---------DIPCYNeWAI 1243
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 160419246  178 EES-SLT-----NTPRKLAkKLKT-SISKATGRKISaalqeespeacllagsvaGAKYHLLAHTTLTLE 239
gi 597587887 1223 EEAtHTS-----SVMSKRGsTs---VQRRAPYK---------------------------VAKLELQLL 1256
gi 399171340 1160 EEAsFAS-----SVKSKRGt-AAAgVVRRAP--------------------------YKI-GKLEVQLL 1195
gi 780598171  293 EEAgFAS-----SVKSKRGn---MaVVRRAP--------------------------YKI-GKLELQLL 326
gi 154305844 1310 EEVsQSSs------------VMSKrSVP-PPVRKRAp----------------yT-----IGKLQLQLL 1344
gi 258574221 1079 DEIpAST-----NNSKNKRnTVALgVQRRPPYR---------------------------VGNLELQLL 1115
gi 528291843 1079 EQLhQSS-----SIMSKRSsTI---FQRKAPYK---------------------------VAKLELQLL 1112
gi 154274163  445 DPV-NNS-----KNKRSMAnSAGSgMQQRPP--------------------------YKI-GNLELQLL 480
gi 295660196 1192 NPVkNNS-----KNKRYMVhSSGSgSTMQ---KQQQq----------------yLPPYRI-GNLELQLL 1235
gi 398405514 1244 DAEsGSSnntsvRSKRg---TTGP--VRRPP--------------------------YIV-GHLELQLL 1280
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