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    Dnajc8 DnaJ heat shock protein family (Hsp40) member C8 [ Mus musculus (house mouse) ]

    Gene ID: 68598, updated on 23-May-2018

    Summary

    Official Symbol
    Dnajc8provided by MGI
    Official Full Name
    DnaJ heat shock protein family (Hsp40) member C8provided by MGI
    Primary source
    MGI:MGI:1915848
    See related
    Ensembl:ENSMUSG00000054405 Vega:OTTMUSG00000009788
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AL024084; AU019262; AU044514; 1110021D09Rik; 2010009J04Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 60.5), liver E14 (RPKM 51.9) and 27 other tissues See more
    Orthologs

    Genomic context

    See Dnajc8 in Genome Data Viewer
    Location:
    4; 4 D2.3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (132535559..132553742)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (132091474..132109657)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene nuclear encoded tRNA alanine 8 (anticodon AGC) Neighboring gene ATPase inhibitory factor 1 Neighboring gene platelet-activating factor receptor Neighboring gene EYA transcriptional coactivator and phosphatase 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    Hsp70 protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    intercellular bridge ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    dnaJ homolog subfamily C member 8
    Names
    DnaJ (Hsp40) homolog, subfamily C, member 8

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172400.3NP_765988.2  dnaJ homolog subfamily C member 8

      See identical proteins and their annotated locations for NP_765988.2

      Status: VALIDATED

      Source sequence(s)
      AK168645, BC064732, BY754536
      Consensus CDS
      CCDS51319.1
      UniProtKB/Swiss-Prot
      Q6NZB0
      UniProtKB/TrEMBL
      A2ALF2
      Related
      ENSMUSP00000092242.3, OTTMUSP00000010345, ENSMUST00000094657.9, OTTMUST00000022667
      Conserved Domains (2) summary
      cd06257
      Location:57112
      DnaJ; DnaJ domain or J-domain. DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s, ...
      COG2214
      Location:51238
      CbpA; Curved DNA-binding protein CbpA, contains a DnaJ-like domain [Transcription]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      132535559..132553742
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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