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    Ppil4 peptidylprolyl isomerase (cyclophilin)-like 4 [ Mus musculus (house mouse) ]

    Gene ID: 67418, updated on 9-Sep-2018

    Summary

    Official Symbol
    Ppil4provided by MGI
    Official Full Name
    peptidylprolyl isomerase (cyclophilin)-like 4provided by MGI
    Primary source
    MGI:MGI:1914668
    See related
    Ensembl:ENSMUSG00000015757 Vega:OTTMUSG00000023636
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PPIase; AI788954; AW146233; 3732410E19Rik; 3830425H19Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 10.7), CNS E14 (RPKM 9.1) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ppil4 in Genome Data Viewer
    Location:
    10; 10 A1
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (7792883..7822565)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (7512692..7542361)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene glycoprotein integral membrane 1 Neighboring gene RIKEN cDNA 6530403G13 gene Neighboring gene zinc finger CCCH type containing 12D Neighboring gene microRNA 5104 Neighboring gene TGF-beta activated kinase 1/MAP3K7 binding protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    • mRNA processing, organism-specific biosystem (from WikiPathways)
      mRNA processing, organism-specific biosystemAdapted from Reactome, see: [http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_1675.1 REACT 1675.1] This process describes the conversion of precursor messenger RNA into mature messenge...

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    peptidyl-prolyl cis-trans isomerase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    protein peptidyl-prolyl isomerization IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of phosphorylation of RNA polymerase II C-terminal domain IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    peptidyl-prolyl cis-trans isomerase-like 4
    Names
    cyclophilin-like protein PPIL4
    rotamase PPIL4
    NP_080417.2
    XP_006512895.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026141.3NP_080417.2  peptidyl-prolyl cis-trans isomerase-like 4

      See identical proteins and their annotated locations for NP_080417.2

      Status: VALIDATED

      Source sequence(s)
      BC079912, BY032114
      Consensus CDS
      CCDS23690.1
      UniProtKB/Swiss-Prot
      Q9CXG3
      Related
      ENSMUSP00000015901.4, OTTMUSP00000027850, ENSMUST00000015901.10, OTTMUST00000057689
      Conserved Domains (3) summary
      COG0724
      Location:193320
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd01921
      Location:4161
      cyclophilin_RRM; cyclophilin_RRM: cyclophilin-type peptidylprolyl cis- trans isomerase domain occuring with a C-terminal RNA recognition motif domain (RRM). This subfamily of the cyclophilin domain family contains a number of eukaryotic cyclophilins having the RRM domain ...
      cd12235
      Location:237319
      RRM_PPIL4; RNA recognition motif in peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      7792883..7822565
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006512832.3XP_006512895.1  peptidyl-prolyl cis-trans isomerase-like 4 isoform X1

      Conserved Domains (3) summary
      COG0724
      Location:193321
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd01921
      Location:4161
      cyclophilin_RRM; cyclophilin_RRM: cyclophilin-type peptidylprolyl cis- trans isomerase domain occuring with a C-terminal RNA recognition motif domain (RRM). This subfamily of the cyclophilin domain family contains a number of eukaryotic cyclophilins having the RRM domain ...
      cd12235
      Location:237319
      RRM_PPIL4; RNA recognition motif in peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) and similar proteins

    RNA

    1. XR_001779581.1 RNA Sequence

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