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    Cstf1 cleavage stimulation factor, 3' pre-RNA, subunit 1 [ Mus musculus (house mouse) ]

    Gene ID: 67337, updated on 19-Feb-2019

    Summary

    Official Symbol
    Cstf1provided by MGI
    Official Full Name
    cleavage stimulation factor, 3' pre-RNA, subunit 1provided by MGI
    Primary source
    MGI:MGI:1914587
    See related
    Ensembl:ENSMUSG00000027498
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI788832; 1700057K18Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 41.6), thymus adult (RPKM 23.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cstf1 in Genome Data Viewer
    Location:
    2 H3; 2 94.84 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (172370686..172382449)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (172196503..172206586)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene predicted gene 14273 Neighboring gene family with sequence similarity 210, member B Neighboring gene aurora kinase A Neighboring gene Cas scaffolding protein family member 4 Neighboring gene replication termination factor 2 Neighboring gene glucosaminyl (N-acetyl) transferase family member 7

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    mRNA cleavage stimulating factor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    cleavage stimulation factor subunit 1
    Names
    CF-1 50 kDa subunit
    CSTF 50 kDa subunit
    cleavage stimulation factor 50 kDa subunit
    cstF-50

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024199.2NP_077161.1  cleavage stimulation factor subunit 1

      See identical proteins and their annotated locations for NP_077161.1

      Status: PROVISIONAL

      Source sequence(s)
      AL833787
      Consensus CDS
      CCDS17130.1
      UniProtKB/Swiss-Prot
      Q99LC2
      Related
      ENSMUSP00000112076.1, ENSMUST00000116375.1
      Conserved Domains (3) summary
      cd00200
      Location:100424
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:116171
      7WD40; WD40 repeat [structural motif]
      pfam16699
      Location:762
      CSTF1_dimer; Cleavage stimulation factor subunit 1, dimerisation domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      172370686..172382449
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500072.3XP_006500135.2  cleavage stimulation factor subunit 1 isoform X1

      See identical proteins and their annotated locations for XP_006500135.2

      UniProtKB/Swiss-Prot
      Q99LC2
      Conserved Domains (3) summary
      cd00200
      Location:100424
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:116171
      7WD40; WD40 repeat [structural motif]
      pfam16699
      Location:762
      CSTF1_dimer; Cleavage stimulation factor subunit 1, dimerisation domain
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