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    Med18 mediator complex subunit 18 [ Mus musculus (house mouse) ]

    Gene ID: 67219, updated on 2-Oct-2018

    Summary

    Official Symbol
    Med18provided by MGI
    Official Full Name
    mediator complex subunit 18provided by MGI
    Primary source
    MGI:MGI:1914469
    See related
    Ensembl:ENSMUSG00000066042 Vega:OTTMUSG00000009673
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2810046C01Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 4.7), liver E14 (RPKM 2.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Med18 in Genome Data Viewer
    Location:
    4; 4 D2.3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (132458729..132463921, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (132014644..132019836, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA, H/ACA box 73a Neighboring gene phosphatase and actin regulator 4 Neighboring gene small nucleolar RNA host gene 3 Neighboring gene sestrin 2 Neighboring gene nuclear encoded tRNA alanine 8 (anticodon AGC)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    transcription coregulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to ubiquitin protein ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    termination of RNA polymerase II transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    core mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mediator complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mediator complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    mediator of RNA polymerase II transcription subunit 18
    Names
    mediator of RNA polymerase II transcription, subunit 18 homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026039.3NP_080315.1  mediator of RNA polymerase II transcription subunit 18

      See identical proteins and their annotated locations for NP_080315.1

      Status: VALIDATED

      Source sequence(s)
      AK012886, AL805897
      Consensus CDS
      CCDS18725.1
      UniProtKB/Swiss-Prot
      Q9CZ82
      Related
      ENSMUSP00000099627.3, OTTMUSP00000010185, ENSMUST00000102567.3, OTTMUST00000022321
      Conserved Domains (1) summary
      pfam09637
      Location:19207
      Med18; Med18 protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      132458729..132463921 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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