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    Med18 mediator complex subunit 18 [ Mus musculus (house mouse) ]

    Gene ID: 67219, updated on 23-Jun-2021

    Summary

    Official Symbol
    Med18provided by MGI
    Official Full Name
    mediator complex subunit 18provided by MGI
    Primary source
    MGI:MGI:1914469
    See related
    Ensembl:ENSMUSG00000066042
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2810046C01Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 4.7), liver E14 (RPKM 2.9) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Med18 in Genome Data Viewer
    Location:
    4; 4 D2.3
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (132186040..132191232, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (132458729..132463921, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (132014644..132019836, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene phosphatase and actin regulator 4 Neighboring gene predicted gene, 23055 Neighboring gene predicted gene, 52758 Neighboring gene sestrin 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in termination of RNA polymerase II transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of core mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of mediator complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of mediator complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mediator of RNA polymerase II transcription subunit 18
    Names
    mediator of RNA polymerase II transcription, subunit 18 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026039.3NP_080315.1  mediator of RNA polymerase II transcription subunit 18

      See identical proteins and their annotated locations for NP_080315.1

      Status: VALIDATED

      Source sequence(s)
      AK012886, AL805897
      Consensus CDS
      CCDS18725.1
      UniProtKB/Swiss-Prot
      Q9CZ82
      Related
      ENSMUSP00000099627.4, ENSMUST00000102567.4
      Conserved Domains (1) summary
      pfam09637
      Location:19207
      Med18; Med18 protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      132186040..132191232 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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