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    Tanc1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 66860, updated on 22-Aug-2021

    Summary

    Official Symbol
    Tanc1provided by MGI
    Official Full Name
    tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1provided by MGI
    Primary source
    MGI:MGI:1914110
    See related
    Ensembl:ENSMUSG00000035168
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tanc; mKIAA1728; 1200003E16Rik
    Expression
    Ubiquitous expression in ovary adult (RPKM 4.4), lung adult (RPKM 3.7) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Tanc1 in Genome Data Viewer
    Location:
    2; 2 C1.1
    Exon count:
    33
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (59442167..59676557)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (59611821..59846213)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (59450101..59684206)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene VISTA enhancer mm717 Neighboring gene mitochondrial ribosomal protein S18B pseudogene Neighboring gene predicted gene, 53240 Neighboring gene VISTA enhancer mm282 Neighboring gene WD repeat, SAM and U-box domain containing 1 Neighboring gene predicted gene, 52554 Neighboring gene bromodomain adjacent to zinc finger domain, 2B Neighboring gene predicted gene 13572

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in axon terminus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in neuronal cell body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    protein TANC1
    Names
    TPR domain, ankyrin-repeat and coiled-coil-containing protein
    tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290659.1NP_001277588.1  protein TANC1 isoform b

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a. The 5' UTR of this variant is incomplete due to a lack of full-length transcript support and splice pattern ambiguity in the upstream region.
      Source sequence(s)
      AK031162, AK079966, BC079914, BY753173, CX769146
      Consensus CDS
      CCDS71057.1
      UniProtKB/Swiss-Prot
      Q0VGY8
      UniProtKB/TrEMBL
      E9QAF9
      Conserved Domains (5) summary
      PHA03095
      Location:8961208
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:12751406
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:12821307
      TPR; TPR repeat [structural motif]
      sd00045
      Location:11351165
      ANK; ANK repeat [structural motif]
      cl39094
      Location:10821306
      Ank_2; Ankyrin repeats (3 copies)
    2. NM_198294.3NP_938036.2  protein TANC1 isoform a

      See identical proteins and their annotated locations for NP_938036.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). The 5'-most non-coding exon of this variant is inferred based on partial transcript alignments.
      Source sequence(s)
      AK031162, AK079966, BC079914, BY753173, CX769146
      Consensus CDS
      CCDS16054.1
      UniProtKB/Swiss-Prot
      Q0VGY8
      Related
      ENSMUSP00000036003.5, ENSMUST00000037526.11
      Conserved Domains (5) summary
      PHA03095
      Location:9031215
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:12821413
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:12891314
      TPR; TPR repeat [structural motif]
      sd00045
      Location:11421172
      ANK; ANK repeat [structural motif]
      cl39094
      Location:10891313
      Ank_2; Ankyrin repeats (3 copies)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      59442167..59676557
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319203.3XP_017174692.1  protein TANC1 isoform X1

      Conserved Domains (6) summary
      PHA03095
      Location:9211233
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:13001431
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:13071332
      TPR; TPR repeat [structural motif]
      sd00045
      Location:11601190
      ANK; ANK repeat [structural motif]
      pfam09606
      Location:15101802
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cl39094
      Location:11071331
      Ank_2; Ankyrin repeats (3 copies)
    2. XM_030251967.1XP_030107827.1  protein TANC1 isoform X4

      Conserved Domains (5) summary
      PHA03095
      Location:8961208
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:12751406
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:12821307
      TPR; TPR repeat [structural motif]
      sd00045
      Location:11351165
      ANK; ANK repeat [structural motif]
      cl39094
      Location:10821306
      Ank_2; Ankyrin repeats (3 copies)
    3. XM_017319205.3XP_017174694.1  protein TANC1 isoform X4

      UniProtKB/TrEMBL
      E9QAF9
      Related
      ENSMUSP00000108187.2, ENSMUST00000112568.8
      Conserved Domains (5) summary
      PHA03095
      Location:8961208
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:12751406
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:12821307
      TPR; TPR repeat [structural motif]
      sd00045
      Location:11351165
      ANK; ANK repeat [structural motif]
      cl39094
      Location:10821306
      Ank_2; Ankyrin repeats (3 copies)
    4. XM_036162490.1XP_036018383.1  protein TANC1 isoform X3

      Related
      ENSMUSP00000123345.3, ENSMUST00000139863.3
      Conserved Domains (5) summary
      PHA03095
      Location:9031215
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:12821413
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:12891314
      TPR; TPR repeat [structural motif]
      sd00045
      Location:11421172
      ANK; ANK repeat [structural motif]
      cl39094
      Location:10891313
      Ank_2; Ankyrin repeats (3 copies)
    5. XM_006500034.5XP_006500097.1  protein TANC1 isoform X1

      See identical proteins and their annotated locations for XP_006500097.1

      Conserved Domains (6) summary
      PHA03095
      Location:9211233
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:13001431
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:13071332
      TPR; TPR repeat [structural motif]
      sd00045
      Location:11601190
      ANK; ANK repeat [structural motif]
      pfam09606
      Location:15101802
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cl39094
      Location:11071331
      Ank_2; Ankyrin repeats (3 copies)
    6. XM_017319200.3XP_017174689.1  protein TANC1 isoform X1

      Conserved Domains (6) summary
      PHA03095
      Location:9211233
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:13001431
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:13071332
      TPR; TPR repeat [structural motif]
      sd00045
      Location:11601190
      ANK; ANK repeat [structural motif]
      pfam09606
      Location:15101802
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cl39094
      Location:11071331
      Ank_2; Ankyrin repeats (3 copies)
    7. XM_030251966.2XP_030107826.1  protein TANC1 isoform X1

      Conserved Domains (6) summary
      PHA03095
      Location:9211233
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:13001431
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:13071332
      TPR; TPR repeat [structural motif]
      sd00045
      Location:11601190
      ANK; ANK repeat [structural motif]
      pfam09606
      Location:15101802
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cl39094
      Location:11071331
      Ank_2; Ankyrin repeats (3 copies)
    8. XM_036162489.1XP_036018382.1  protein TANC1 isoform X3

      Conserved Domains (5) summary
      PHA03095
      Location:9031215
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:12821413
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:12891314
      TPR; TPR repeat [structural motif]
      sd00045
      Location:11421172
      ANK; ANK repeat [structural motif]
      cl39094
      Location:10891313
      Ank_2; Ankyrin repeats (3 copies)
    9. XM_036162492.1XP_036018385.1  protein TANC1 isoform X4

      Conserved Domains (5) summary
      PHA03095
      Location:8961208
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:12751406
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:12821307
      TPR; TPR repeat [structural motif]
      sd00045
      Location:11351165
      ANK; ANK repeat [structural motif]
      cl39094
      Location:10821306
      Ank_2; Ankyrin repeats (3 copies)
    10. XM_006500037.5XP_006500100.1  protein TANC1 isoform X2

      Conserved Domains (6) summary
      PHA03095
      Location:9141226
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:12931424
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:13001325
      TPR; TPR repeat [structural motif]
      sd00045
      Location:11531183
      ANK; ANK repeat [structural motif]
      pfam09606
      Location:15031795
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cl39094
      Location:11001324
      Ank_2; Ankyrin repeats (3 copies)
    11. XM_017319204.3XP_017174693.1  protein TANC1 isoform X1

      Conserved Domains (6) summary
      PHA03095
      Location:9211233
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:13001431
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:13071332
      TPR; TPR repeat [structural motif]
      sd00045
      Location:11601190
      ANK; ANK repeat [structural motif]
      pfam09606
      Location:15101802
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cl39094
      Location:11071331
      Ank_2; Ankyrin repeats (3 copies)
    12. XM_036162491.1XP_036018384.1  protein TANC1 isoform X4

      Conserved Domains (5) summary
      PHA03095
      Location:8961208
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:12751406
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:12821307
      TPR; TPR repeat [structural motif]
      sd00045
      Location:11351165
      ANK; ANK repeat [structural motif]
      cl39094
      Location:10821306
      Ank_2; Ankyrin repeats (3 copies)
    13. XM_017319202.3XP_017174691.1  protein TANC1 isoform X1

      Conserved Domains (6) summary
      PHA03095
      Location:9211233
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:13001431
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:13071332
      TPR; TPR repeat [structural motif]
      sd00045
      Location:11601190
      ANK; ANK repeat [structural motif]
      pfam09606
      Location:15101802
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cl39094
      Location:11071331
      Ank_2; Ankyrin repeats (3 copies)
    14. XM_006500036.5XP_006500099.1  protein TANC1 isoform X1

      See identical proteins and their annotated locations for XP_006500099.1

      Conserved Domains (6) summary
      PHA03095
      Location:9211233
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:13001431
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:13071332
      TPR; TPR repeat [structural motif]
      sd00045
      Location:11601190
      ANK; ANK repeat [structural motif]
      pfam09606
      Location:15101802
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cl39094
      Location:11071331
      Ank_2; Ankyrin repeats (3 copies)
    15. XM_006500039.3XP_006500102.1  protein TANC1 isoform X5

      Conserved Domains (6) summary
      PHA03095
      Location:7031015
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:10821213
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:10891114
      TPR; TPR repeat [structural motif]
      sd00045
      Location:942972
      ANK; ANK repeat [structural motif]
      pfam09606
      Location:12921584
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cl39094
      Location:8891113
      Ank_2; Ankyrin repeats (3 copies)
    16. XM_006500040.5XP_006500103.1  protein TANC1 isoform X6

      Conserved Domains (6) summary
      PHA03095
      Location:599911
      PHA03095; ankyrin-like protein; Provisional
      COG0457
      Location:9781109
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:9851010
      TPR; TPR repeat [structural motif]
      sd00045
      Location:838868
      ANK; ANK repeat [structural motif]
      pfam09606
      Location:11881480
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      cl39094
      Location:7851009
      Ank_2; Ankyrin repeats (3 copies)
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