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TANC1 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 [ Homo sapiens (human) ]

Gene ID: 85461, updated on 21-Dec-2019

Summary

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Official Symbol
TANC1provided by HGNC
Official Full Name
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1provided by HGNC
Primary source
HGNC:HGNC:29364
See related
Ensembl:ENSG00000115183 MIM:611397
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
TANC; ROLSB
Expression
Ubiquitous expression in skin (RPKM 16.4), lung (RPKM 9.9) and 24 other tissues See more
Orthologs
mouse all

Genomic context

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See TANC1 in Genome Data Viewer
Location:
2q24.2
Exon count:
34
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (158968600..159232659)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (159825146..160089170)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene VISTA enhancer hs1477 Neighboring gene RNA, U2 small nuclear 21, pseudogene Neighboring gene VISTA enhancer hs2027 Neighboring gene basic transcription factor 3 like 4 pseudogene 2 Neighboring gene RNA, U6 small nuclear 580, pseudogene Neighboring gene glutathione S-transferase mu 3 pseudogene 2 Neighboring gene uncharacterized LOC105373716 Neighboring gene microRNA 6888 Neighboring gene WD repeat, sterile alpha motif and U-box domain containing 1 Neighboring gene bromodomain adjacent to zinc finger domain 2B Neighboring gene CAPZA1 pseudogene 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

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Related articles in PubMed

  1. Complex chromosomal rearrangement in a girl with psychomotor-retardation and a de novo inversion: inv(2)(p15;q24.2). Granot-Hershkovitz E, et al. Am J Med Genet A, 2011 Aug. PMID 21739571
  2. A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24.1. Fachal L, et al. Nat Genet, 2014 Aug. PMID 24974847
  3. Drosophila and mammalian models uncover a role for the myoblast fusion gene TANC1 in rhabdomyosarcoma. Avirneni-Vadlamudi U, et al. J Clin Invest, 2012 Jan. PMID 22182840, Free PMC Article
  4. A novel scaffold protein, TANC, possibly a rat homolog of Drosophila rolling pebbles (rols), forms a multiprotein complex with various postsynaptic density proteins. Suzuki T, et al. Eur J Neurosci, 2005 Jan. PMID 15673434
  5. GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease. Aouizerat BE, et al. BMC Cardiovasc Disord, 2011 Jun 10. PMID 21658281, Free PMC Article

See all (25) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Discusses cloning and expression of Rat TANC1 and preliminary cloning of human TANC1, which resulted in recovery of a partial cDNA.
    Title: A novel scaffold protein, TANC, possibly a rat homolog of Drosophila rolling pebbles (rols), forms a multiprotein complex with various postsynaptic density proteins.
Submit: New GeneRIF Correction

Phenotypes

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Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

NHGRI GWAS Catalog

Description
A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24.1.
NHGRI GWA Catalog
GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.
NHGRI GWA Catalog

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Genotypes

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • FLJ13360, FLJ41166, KIAA1728

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
dendritic spine maintenance IEA
Inferred from Electronic Annotation
more info
  
myoblast fusion IEA
Inferred from Electronic Annotation
more info
  
visual learning IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
axon terminus IEA
Inferred from Electronic Annotation
more info
  
cell junction IEA
Inferred from Electronic Annotation
more info
  
dendrite IEA
Inferred from Electronic Annotation
more info
  
neuronal cell body IEA
Inferred from Electronic Annotation
more info
  
postsynaptic density IEA
Inferred from Electronic Annotation
more info
  
postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
protein TANC1
Names
TPR domain, ankyrin-repeat and coiled-coil-containing
rolling pebbles homolog B
tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145909.1 → NP_001139381.1  protein TANC1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has multiple differences in the coding region, compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC009307, AC010093, AL833258, BC037329, BC150597, DA226268
    UniProtKB/Swiss-Prot
    Q9C0D5
    UniProtKB/TrEMBL
    B9EK39
    Conserved Domains (7) summary
    cd00204
    Location:1100 → 1223
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1284 → 1309
    TPR; TPR repeat [structural motif]
    pfam12796
    Location:1108 → 1200
    Ank_2; Ankyrin repeats (3 copies)
    pfam13191
    Location:377 → 419
    AAA_16; AAA ATPase domain
    pfam13414
    Location:1282 → 1359
    TPR_11; TPR repeat
    pfam13637
    Location:930 → 979
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:1137 → 1167
    ANK; ANK repeat [structural motif]

  2. NM_001350062.1 → NP_001336991.1  protein TANC1 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) encodes isoform 3.
    Source sequence(s)
    AC009307, AC010093
    Conserved Domains (4) summary
    COG0457
    Location:1061 → 1215
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    cd00204
    Location:907 → 1030
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1091 → 1116
    TPR; TPR repeat [structural motif]
    sd00045
    Location:944 → 974
    ANK; ANK repeat [structural motif]

  3. NM_001350063.1 → NP_001336992.1  protein TANC1 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) encodes isoform 4.
    Source sequence(s)
    AC009307, AC010093
    Conserved Domains (4) summary
    COG0457
    Location:1139 → 1293
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    cd00204
    Location:985 → 1108
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1169 → 1194
    TPR; TPR repeat [structural motif]
    sd00045
    Location:1022 → 1052
    ANK; ANK repeat [structural motif]

  4. NM_001350064.1 → NP_001336993.1  protein TANC1 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5), as well as variant 6, encodes isoform 5.
    Source sequence(s)
    AC009307, AC010093
    Conserved Domains (4) summary
    COG0457
    Location:1255 → 1409
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    cd00204
    Location:1101 → 1224
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1285 → 1310
    TPR; TPR repeat [structural motif]
    sd00045
    Location:1138 → 1168
    ANK; ANK repeat [structural motif]

  5. NM_001350065.1 → NP_001336994.1  protein TANC1 isoform 5

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6), as well as variant 5, encodes isoform 5.
    Source sequence(s)
    AC009307, AC010093
    Conserved Domains (4) summary
    COG0457
    Location:1255 → 1409
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    cd00204
    Location:1101 → 1224
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1285 → 1310
    TPR; TPR repeat [structural motif]
    sd00045
    Location:1138 → 1168
    ANK; ANK repeat [structural motif]

  6. NM_033394.3 → NP_203752.2  protein TANC1 isoform 1

    See identical proteins and their annotated locations for NP_203752.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC009307, AK128859, AL833258, BC037329, BC150597, BX648327
    Consensus CDS
    CCDS42766.1
    UniProtKB/Swiss-Prot
    Q9C0D5
    UniProtKB/TrEMBL
    B9EK39
    Related
    ENSP00000263635.6, ENST00000263635.8
    Conserved Domains (8) summary
    cd00204
    Location:1108 → 1231
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1292 → 1317
    TPR; TPR repeat [structural motif]
    pfam12796
    Location:1116 → 1208
    Ank_2; Ankyrin repeats (3 copies)
    pfam13191
    Location:385 → 427
    AAA_16; AAA ATPase domain
    pfam13414
    Location:1290 → 1367
    TPR_11; TPR repeat
    pfam13428
    Location:1371 → 1413
    TPR_14; Tetratricopeptide repeat
    pfam13637
    Location:938 → 987
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:1145 → 1175
    ANK; ANK repeat [structural motif]

RNA

  1. NR_146421.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC010093

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    158968600..159232659
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017005142.1 → XP_016860631.1  protein TANC1 isoform X3

  2. XM_006712810.3 → XP_006712873.1  protein TANC1 isoform X8

    See identical proteins and their annotated locations for XP_006712873.1

    UniProtKB/Swiss-Prot
    Q9C0D5
    Conserved Domains (8) summary
    cd00204
    Location:1108 → 1231
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1292 → 1317
    TPR; TPR repeat [structural motif]
    pfam12796
    Location:1116 → 1208
    Ank_2; Ankyrin repeats (3 copies)
    pfam13191
    Location:385 → 427
    AAA_16; AAA ATPase domain
    pfam13414
    Location:1290 → 1367
    TPR_11; TPR repeat
    pfam13428
    Location:1371 → 1413
    TPR_14; Tetratricopeptide repeat
    pfam13637
    Location:938 → 987
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:1145 → 1175
    ANK; ANK repeat [structural motif]

  3. XM_011512055.2 → XP_011510357.1  protein TANC1 isoform X10

    Conserved Domains (8) summary
    cd00204
    Location:1100 → 1223
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1284 → 1309
    TPR; TPR repeat [structural motif]
    pfam12796
    Location:1108 → 1200
    Ank_2; Ankyrin repeats (3 copies)
    pfam13191
    Location:377 → 419
    AAA_16; AAA ATPase domain
    pfam13414
    Location:1282 → 1359
    TPR_11; TPR repeat
    pfam13428
    Location:1363 → 1405
    TPR_14; Tetratricopeptide repeat
    pfam13637
    Location:930 → 979
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:1137 → 1167
    ANK; ANK repeat [structural motif]

  4. XM_011512058.2 → XP_011510360.1  protein TANC1 isoform X18

    UniProtKB/Swiss-Prot
    Q9C0D5
    Conserved Domains (8) summary
    cd00204
    Location:1002 → 1125
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1186 → 1211
    TPR; TPR repeat [structural motif]
    pfam12796
    Location:1010 → 1102
    Ank_2; Ankyrin repeats (3 copies)
    pfam13191
    Location:279 → 321
    AAA_16; AAA ATPase domain
    pfam13414
    Location:1184 → 1261
    TPR_11; TPR repeat
    pfam13428
    Location:1265 → 1307
    TPR_14; Tetratricopeptide repeat
    pfam13637
    Location:832 → 881
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:1039 → 1069
    ANK; ANK repeat [structural motif]

  5. XM_006712812.3 → XP_006712875.1  protein TANC1 isoform X12

    Conserved Domains (8) summary
    cd00204
    Location:1073 → 1196
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1257 → 1282
    TPR; TPR repeat [structural motif]
    pfam12796
    Location:1081 → 1173
    Ank_2; Ankyrin repeats (3 copies)
    pfam13191
    Location:350 → 392
    AAA_16; AAA ATPase domain
    pfam13414
    Location:1255 → 1332
    TPR_11; TPR repeat
    pfam13428
    Location:1336 → 1378
    TPR_14; Tetratricopeptide repeat
    pfam13637
    Location:903 → 952
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:1110 → 1140
    ANK; ANK repeat [structural motif]

  6. XM_017005146.1 → XP_016860635.1  protein TANC1 isoform X6

  7. XM_011512048.2 → XP_011510350.1  protein TANC1 isoform X2

    Conserved Domains (8) summary
    cd00204
    Location:1132 → 1255
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1316 → 1341
    TPR; TPR repeat [structural motif]
    pfam12796
    Location:1140 → 1232
    Ank_2; Ankyrin repeats (3 copies)
    pfam13191
    Location:409 → 451
    AAA_16; AAA ATPase domain
    pfam13414
    Location:1314 → 1391
    TPR_11; TPR repeat
    pfam13428
    Location:1395 → 1437
    TPR_14; Tetratricopeptide repeat
    pfam13637
    Location:962 → 1011
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:1169 → 1199
    ANK; ANK repeat [structural motif]

  8. XM_017005145.1 → XP_016860634.1  protein TANC1 isoform X5

    Conserved Domains (8) summary
    cd00204
    Location:1126 → 1249
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1310 → 1335
    TPR; TPR repeat [structural motif]
    pfam12796
    Location:1134 → 1226
    Ank_2; Ankyrin repeats (3 copies)
    pfam13191
    Location:403 → 445
    AAA_16; AAA ATPase domain
    pfam13414
    Location:1308 → 1385
    TPR_11; TPR repeat
    pfam13428
    Location:1389 → 1431
    TPR_14; Tetratricopeptide repeat
    pfam13637
    Location:956 → 1005
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:1163 → 1193
    ANK; ANK repeat [structural motif]

  9. XM_017005154.1 → XP_016860643.1  protein TANC1 isoform X16

  10. XM_011512051.2 → XP_011510353.1  protein TANC1 isoform X5

    See identical proteins and their annotated locations for XP_011510353.1

    Conserved Domains (8) summary
    cd00204
    Location:1126 → 1249
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1310 → 1335
    TPR; TPR repeat [structural motif]
    pfam12796
    Location:1134 → 1226
    Ank_2; Ankyrin repeats (3 copies)
    pfam13191
    Location:403 → 445
    AAA_16; AAA ATPase domain
    pfam13414
    Location:1308 → 1385
    TPR_11; TPR repeat
    pfam13428
    Location:1389 → 1431
    TPR_14; Tetratricopeptide repeat
    pfam13637
    Location:956 → 1005
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:1163 → 1193
    ANK; ANK repeat [structural motif]

  11. XM_011512053.2 → XP_011510355.1  protein TANC1 isoform X5

    See identical proteins and their annotated locations for XP_011510355.1

    Conserved Domains (8) summary
    cd00204
    Location:1126 → 1249
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1310 → 1335
    TPR; TPR repeat [structural motif]
    pfam12796
    Location:1134 → 1226
    Ank_2; Ankyrin repeats (3 copies)
    pfam13191
    Location:403 → 445
    AAA_16; AAA ATPase domain
    pfam13414
    Location:1308 → 1385
    TPR_11; TPR repeat
    pfam13428
    Location:1389 → 1431
    TPR_14; Tetratricopeptide repeat
    pfam13637
    Location:956 → 1005
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:1163 → 1193
    ANK; ANK repeat [structural motif]

  12. XM_006712814.3 → XP_006712877.1  protein TANC1 isoform X22

    Conserved Domains (8) summary
    cd00204
    Location:924 → 1047
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1108 → 1133
    TPR; TPR repeat [structural motif]
    pfam12796
    Location:932 → 1024
    Ank_2; Ankyrin repeats (3 copies)
    pfam13191
    Location:201 → 243
    AAA_16; AAA ATPase domain
    pfam13414
    Location:1106 → 1183
    TPR_11; TPR repeat
    pfam13428
    Location:1187 → 1229
    TPR_14; Tetratricopeptide repeat
    pfam13637
    Location:754 → 803
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:961 → 991
    ANK; ANK repeat [structural motif]

  13. XM_005246918.4 → XP_005246975.1  protein TANC1 isoform X7

    Conserved Domains (8) summary
    cd00204
    Location:1118 → 1241
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1302 → 1327
    TPR; TPR repeat [structural motif]
    pfam12796
    Location:1126 → 1218
    Ank_2; Ankyrin repeats (3 copies)
    pfam13191
    Location:395 → 437
    AAA_16; AAA ATPase domain
    pfam13414
    Location:1300 → 1377
    TPR_11; TPR repeat
    pfam13428
    Location:1381 → 1423
    TPR_14; Tetratricopeptide repeat
    pfam13637
    Location:948 → 997
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:1155 → 1185
    ANK; ANK repeat [structural motif]

  14. XM_017005150.1 → XP_016860639.1  protein TANC1 isoform X11

  15. XM_017005151.1 → XP_016860640.1  protein TANC1 isoform X13

  16. XM_017005141.1 → XP_016860630.1  protein TANC1 isoform X1

  17. XM_017005144.1 → XP_016860633.1  protein TANC1 isoform X4

  18. XM_017005152.1 → XP_016860641.1  protein TANC1 isoform X14

  19. XM_017005153.1 → XP_016860642.1  protein TANC1 isoform X15

  20. XM_017005156.1 → XP_016860645.1  protein TANC1 isoform X20

  21. XM_024453194.1 → XP_024308962.1  protein TANC1 isoform X21

    Conserved Domains (4) summary
    COG0457
    Location:1079 → 1233
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    cd00204
    Location:925 → 1048
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1109 → 1134
    TPR; TPR repeat [structural motif]
    sd00045
    Location:962 → 992
    ANK; ANK repeat [structural motif]

  22. XM_017005149.1 → XP_016860638.1  protein TANC1 isoform X9

  23. XM_024453193.1 → XP_024308961.1  protein TANC1 isoform X17

    Conserved Domains (4) summary
    COG0457
    Location:1157 → 1311
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    cd00204
    Location:1003 → 1126
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1187 → 1212
    TPR; TPR repeat [structural motif]
    sd00045
    Location:1040 → 1070
    ANK; ANK repeat [structural motif]

  24. XM_017005143.2 → XP_016860632.1  protein TANC1 isoform X3

  25. XM_011512059.2 → XP_011510361.1  protein TANC1 isoform X19

    Conserved Domains (8) summary
    cd00204
    Location:944 → 1067
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:1128 → 1153
    TPR; TPR repeat [structural motif]
    pfam12796
    Location:952 → 1044
    Ank_2; Ankyrin repeats (3 copies)
    pfam13191
    Location:221 → 263
    AAA_16; AAA ATPase domain
    pfam13414
    Location:1126 → 1203
    TPR_11; TPR repeat
    pfam13428
    Location:1207 → 1249
    TPR_14; Tetratricopeptide repeat
    pfam13637
    Location:774 → 823
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:981 → 1011
    ANK; ANK repeat [structural motif]

  26. XM_011512062.2 → XP_011510364.1  protein TANC1 isoform X23

    Conserved Domains (8) summary
    cd00204
    Location:801 → 924
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00006
    Location:985 → 1010
    TPR; TPR repeat [structural motif]
    pfam12796
    Location:809 → 901
    Ank_2; Ankyrin repeats (3 copies)
    pfam13191
    Location:78 → 120
    AAA_16; AAA ATPase domain
    pfam13414
    Location:983 → 1060
    TPR_11; TPR repeat
    pfam13428
    Location:1064 → 1106
    TPR_14; Tetratricopeptide repeat
    pfam13637
    Location:631 → 680
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:838 → 868
    ANK; ANK repeat [structural motif]

RNA

  1. XR_002959353.1 RNA Sequence

  2. XR_002959352.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9C0D5.3 GenPept UniProtKB/Swiss-Prot:Q9C0D5

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