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    Thap11 THAP domain containing 11 [ Mus musculus (house mouse) ]

    Gene ID: 59016, updated on 26-Sep-2022

    Summary

    Official Symbol
    Thap11provided by MGI
    Official Full Name
    THAP domain containing 11provided by MGI
    Primary source
    MGI:MGI:1930964
    See related
    Ensembl:ENSMUSG00000036442 AllianceGenome:MGI:1930964
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ronin; CTG-B43a; CTG-B45d; 2810036E22Rik
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and zinc ion binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be located in cytosol. Predicted to be active in nucleoplasm. Is expressed in 1-cell stage embryo; brain ventricular layer; forelimb bud; inferior colliculus; and oocyte. Orthologous to human THAP11 (THAP domain containing 11). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See Thap11 in Genome Data Viewer
    Location:
    8; 8 D3
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (106581735..106583582)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (105855103..105856950)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene RAN binding protein 10 Neighboring gene translin-associated factor X (Tsnax) interacting protein 1 Neighboring gene centromere protein T Neighboring gene nuclear transport factor 2 Neighboring gene enhancer of mRNA decapping 4

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    part_of RNA polymerase II transcription regulator complex IC
    Inferred by Curator
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    THAP domain-containing protein 11

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021513.2NP_067488.1  THAP domain-containing protein 11

      See identical proteins and their annotated locations for NP_067488.1

      Status: VALIDATED

      Source sequence(s)
      AC116569
      Consensus CDS
      CCDS22616.1
      UniProtKB/Swiss-Prot
      Q99KZ0, Q9JJD0
      Related
      ENSMUSP00000048994.8, ENSMUST00000040445.9
      Conserved Domains (1) summary
      pfam05485
      Location:581
      THAP; THAP domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      106581735..106583582
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)