Format

Send to:

Choose Destination
    • Showing Current items.

    Dstn destrin [ Mus musculus (house mouse) ]

    Gene ID: 56431, updated on 31-Jan-2019

    Summary

    Official Symbol
    Dstnprovided by MGI
    Official Full Name
    destrinprovided by MGI
    Primary source
    MGI:MGI:1929270
    See related
    Ensembl:ENSMUSG00000015932
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ADF; Dsn; corn1; sid23p; AU042046; 2610043P17Rik
    Expression
    Biased expression in bladder adult (RPKM 498.8), large intestine adult (RPKM 115.0) and 14 other tissues See more
    Orthologs

    Genomic context

    See Dstn in Genome Data Viewer
    Location:
    2 G1; 2 70.89 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (143915331..143943324)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (143741067..143769060)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene beaded filament structural protein 1, in lens-CP94 Neighboring gene predicted gene, 33648 Neighboring gene 60S ribosomal protein L35a pseudogene Neighboring gene predicted gene, 33804 Neighboring gene ribosome binding protein 1 Neighboring gene barrier to autointegration factor 2 Neighboring gene barrier to autointegration factor 2, opposite strand

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    actin filament binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    actin filament binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    actin filament depolymerization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    actin filament depolymerization ISO
    Inferred from Sequence Orthology
    more info
     
    actin filament fragmentation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    actin filament severing IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of actin filament depolymerization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cortical actin cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    destrin
    Names
    actin-depolymerizing factor
    corneal disease 1
    sid 23

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019771.2NP_062745.1  destrin

      See identical proteins and their annotated locations for NP_062745.1

      Status: VALIDATED

      Source sequence(s)
      AB025406, BF123977
      Consensus CDS
      CCDS16812.1
      UniProtKB/Swiss-Prot
      Q9R0P5
      UniProtKB/TrEMBL
      Q4FK36
      Related
      ENSMUSP00000099461.3, ENSMUST00000103172.3
      Conserved Domains (1) summary
      cd11286
      Location:3152
      ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      143915331..143943324
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center