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    Dstn destrin [ Mus musculus (house mouse) ]

    Gene ID: 56431, updated on 5-Sep-2021

    Summary

    Official Symbol
    Dstnprovided by MGI
    Official Full Name
    destrinprovided by MGI
    Primary source
    MGI:MGI:1929270
    See related
    Ensembl:ENSMUSG00000015932
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AD; co; ADF; Dsn; sid; corn1; sid23p; AU042046; 2610043P17Rik
    Expression
    Biased expression in bladder adult (RPKM 498.8), large intestine adult (RPKM 115.0) and 14 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Dstn in Genome Data Viewer
    Location:
    2 G1; 2 70.89 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (143757251..143785244)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (143915331..143943324)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (143741067..143769060)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene beaded filament structural protein 1, in lens-CP94 Neighboring gene predicted gene, 33648 Neighboring gene predicted gene 11686 Neighboring gene predicted gene, 33804 Neighboring gene predicted gene, 54119 Neighboring gene ribosome binding protein 1 Neighboring gene BANF family member 2 Neighboring gene barrier to autointegration factor 2, opposite strand

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables actin filament binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables actin filament binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cortical actin cytoskeleton IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    destrin
    Names
    actin-depolymerizing factor
    corneal disease 1
    sid 23

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019771.2NP_062745.1  destrin

      See identical proteins and their annotated locations for NP_062745.1

      Status: VALIDATED

      Source sequence(s)
      AB025406, BF123977
      Consensus CDS
      CCDS16812.1
      UniProtKB/Swiss-Prot
      Q9R0P5
      UniProtKB/TrEMBL
      Q4FK36
      Related
      ENSMUSP00000099461.4, ENSMUST00000103172.4
      Conserved Domains (1) summary
      cd11286
      Location:3152
      ADF_cofilin_like; Cofilin, Destrin, and related actin depolymerizing factors

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      143757251..143785244
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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