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    Dnal4 dynein, axonemal, light chain 4 [ Mus musculus (house mouse) ]

    Gene ID: 54152, updated on 9-Sep-2018

    Summary

    Official Symbol
    Dnal4provided by MGI
    Official Full Name
    dynein, axonemal, light chain 4provided by MGI
    Primary source
    MGI:MGI:1859217
    See related
    Ensembl:ENSMUSG00000022420 Vega:OTTMUSG00000034900
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dnalc4; D15Ertd424e
    Expression
    Ubiquitous expression in testis adult (RPKM 61.0), whole brain E14.5 (RPKM 24.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Dnal4 in Genome Data Viewer
    Location:
    15 E1; 15 37.85 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (79761449..79774467, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (79591879..79604897, complement)

    Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene Sad1 and UNC84 domain containing 2 Neighboring gene predicted gene 16576 Neighboring gene predicted gene, 30977 Neighboring gene neuronal pentraxin receptor Neighboring gene neuronal pentraxin chromo domain Neighboring gene chromobox 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to ATP-dependent microtubule motor activity, plus-end-directed IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    dynein intermediate chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    dynein light intermediate chain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    motor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    microtubule-based process IEA
    Inferred from Electronic Annotation
    more info
     
    positive regulation of ATP-dependent microtubule motor activity, plus-end-directed IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    cilium IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    dynein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    dynein light chain 4, axonemal
    Names
    dynein, axon, light chain 4
    outer arm dynein light chain 4

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_017470.2NP_059498.2  dynein light chain 4, axonemal

      See identical proteins and their annotated locations for NP_059498.2

      Status: VALIDATED

      Source sequence(s)
      AK132061, BE951989, BY012683
      Consensus CDS
      CCDS27650.1
      UniProtKB/Swiss-Prot
      Q9DCM4
      Related
      ENSMUSP00000023055.6, OTTMUSP00000048394, ENSMUST00000023055.7, OTTMUST00000088726
      Conserved Domains (1) summary
      pfam01221
      Location:20103
      Dynein_light; Dynein light chain type 1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

      Range
      79761449..79774467 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006521170.2XP_006521233.1  dynein light chain 4, axonemal isoform X1

      See identical proteins and their annotated locations for XP_006521233.1

      UniProtKB/Swiss-Prot
      Q9DCM4
      Related
      ENSMUSP00000154848.1, ENSMUST00000162713.8
      Conserved Domains (1) summary
      pfam01221
      Location:20103
      Dynein_light; Dynein light chain type 1
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