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    Ppp1r10 protein phosphatase 1, regulatory subunit 10 [ Mus musculus (house mouse) ]

    Gene ID: 52040, updated on 16-Oct-2021

    Summary

    Official Symbol
    Ppp1r10provided by MGI
    Official Full Name
    protein phosphatase 1, regulatory subunit 10provided by MGI
    Primary source
    MGI:MGI:1289273
    See related
    Ensembl:ENSMUSG00000039220
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fb19; Cat53; Pnuts; D17Ertd808e; 2610025H06Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 26.6), thymus adult (RPKM 16.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ppp1r10 in Genome Data Viewer
    Location:
    17 B1; 17 18.77 cM
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (36227404..36243175)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (35916512..35932283)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (36053856..36069228)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene alpha tubulin acetyltransferase 1 Neighboring gene predicted gene 16279 Neighboring gene mitochondrial ribosomal protein S18B Neighboring gene microRNA 1894 Neighboring gene ring-box 1, pseudogene Neighboring gene protein phosphatase 1, regulatory subunit 10 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Transgenic (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein phosphatase 1 binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein phosphatase inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of PTW/PP1 phosphatase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with chromosome, telomeric region ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    serine/threonine-protein phosphatase 1 regulatory subunit 10
    Names
    HLA-C adjacent transcript 53
    MHC class I region proline-rich protein CAT53
    protein phosphatase I

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163818.1NP_001157290.1  serine/threonine-protein phosphatase 1 regulatory subunit 10

      See identical proteins and their annotated locations for NP_001157290.1

      Status: VALIDATED

      Source sequence(s)
      AW456628, BC052059
      Consensus CDS
      CCDS50098.1
      UniProtKB/Swiss-Prot
      Q80W00
      Related
      ENSMUSP00000084460.7, ENSMUST00000087210.7
      Conserved Domains (2) summary
      pfam18044
      Location:858880
      zf-CCCH_4; CCCH-type zinc finger
      cl00146
      Location:102146
      TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme
    2. NM_001357740.1NP_001344669.1  serine/threonine-protein phosphatase 1 regulatory subunit 10

      Status: VALIDATED

      Source sequence(s)
      AJ504718, CR974451
      Consensus CDS
      CCDS50098.1
      Conserved Domains (2) summary
      pfam18044
      Location:858880
      zf-CCCH_4; CCCH-type zinc finger
      cl00146
      Location:102146
      TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      36227404..36243175
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036160685.1XP_036016578.1  serine/threonine-protein phosphatase 1 regulatory subunit 10 isoform X1

      Conserved Domains (2) summary
      pfam18044
      Location:858880
      zf-CCCH_4; CCCH-type zinc finger
      cl00146
      Location:102146
      TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme
    2. XM_006524617.2XP_006524680.1  serine/threonine-protein phosphatase 1 regulatory subunit 10 isoform X1

      See identical proteins and their annotated locations for XP_006524680.1

      UniProtKB/Swiss-Prot
      Q80W00
      Related
      ENSMUSP00000084461.3, ENSMUST00000087211.9
      Conserved Domains (2) summary
      pfam18044
      Location:858880
      zf-CCCH_4; CCCH-type zinc finger
      cl00146
      Location:102146
      TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme
    3. XM_006524619.3XP_006524682.1  serine/threonine-protein phosphatase 1 regulatory subunit 10 isoform X1

      See identical proteins and their annotated locations for XP_006524682.1

      UniProtKB/Swiss-Prot
      Q80W00
      Conserved Domains (2) summary
      pfam18044
      Location:858880
      zf-CCCH_4; CCCH-type zinc finger
      cl00146
      Location:102146
      TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme
    4. XM_030249898.2XP_030105758.1  serine/threonine-protein phosphatase 1 regulatory subunit 10 isoform X1

      Conserved Domains (2) summary
      pfam18044
      Location:858880
      zf-CCCH_4; CCCH-type zinc finger
      cl00146
      Location:102146
      TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme
    5. XM_006524616.4XP_006524679.1  serine/threonine-protein phosphatase 1 regulatory subunit 10 isoform X1

      See identical proteins and their annotated locations for XP_006524679.1

      UniProtKB/Swiss-Prot
      Q80W00
      Conserved Domains (2) summary
      pfam18044
      Location:858880
      zf-CCCH_4; CCCH-type zinc finger
      cl00146
      Location:102146
      TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_175934.3: Suppressed sequence

      Description
      NM_175934.3: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein
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