Format

Send to:

Choose Destination
    • Showing Current items.

    Kctd18 potassium channel tetramerisation domain containing 18 [ Mus musculus (house mouse) ]

    Gene ID: 51960, updated on 23-Jun-2021

    Summary

    Official Symbol
    Kctd18provided by MGI
    Official Full Name
    potassium channel tetramerisation domain containing 18provided by MGI
    Primary source
    MGI:MGI:3603813
    See related
    Ensembl:ENSMUSG00000054770
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4932411A20Rik; 6530404F10Rik
    Expression
    Ubiquitous expression in CNS E18 (RPKM 4.0), CNS E14 (RPKM 3.8) and 27 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Kctd18 in Genome Data Viewer
    Location:
    1; 1 C1.3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (57994260..58009298, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (57955101..57970141, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (58011945..58026928, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA48 Neighboring gene spermatogenesis associated, serine-rich 2-like Neighboring gene small nucleolar RNA U13 Neighboring gene shugoshin 2A Neighboring gene aldehyde oxidase 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    BTB/POZ domain-containing protein KCTD18

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001159864.1NP_001153336.1  BTB/POZ domain-containing protein KCTD18 isoform 1

      See identical proteins and their annotated locations for NP_001153336.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AC110735, AK132699, BB678909, BY080515, BY736102
      Consensus CDS
      CCDS48269.1
      UniProtKB/TrEMBL
      E0CZ26
      Related
      ENSMUSP00000110052.4, ENSMUST00000114410.10
      Conserved Domains (2) summary
      cd18372
      Location:23123
      BTB_POZ_KCTD18; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing protein 18 (KCTD18)
      pfam17669
      Location:339414
      DUF5529; Family of unknown function (DUF5529)
    2. NM_001159865.1NP_001153337.1  BTB/POZ domain-containing protein KCTD18 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame segment compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      BB678909, BC075692, BY080515, CA530605
      Consensus CDS
      CCDS48268.1
      UniProtKB/TrEMBL
      E9Q945, Q6DI85
      Related
      ENSMUSP00000130952.2, ENSMUST00000164963.8
      Conserved Domains (1) summary
      cl38908
      Location:23107
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily

    RNA

    1. NR_027630.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' end and at the 3' end of an internal exon compared to variant 1. The resulting transcript is a candidate for nonsense-mediated mRNA decay (NMD) and is therefore thought to be a noncoding transcript.
      Source sequence(s)
      BB678909, BC075692
      Related
      ENSMUST00000161608.8

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      57994260..58009298 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496136.5XP_006496199.1  BTB/POZ domain-containing protein KCTD18 isoform X1

      See identical proteins and their annotated locations for XP_006496199.1

      UniProtKB/TrEMBL
      E0CZ26
      Conserved Domains (2) summary
      cd18372
      Location:23123
      BTB_POZ_KCTD18; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing protein 18 (KCTD18)
      pfam17669
      Location:339414
      DUF5529; Family of unknown function (DUF5529)
    2. XM_036152324.1XP_036008217.1  BTB/POZ domain-containing protein KCTD18 isoform X3

      Conserved Domains (1) summary
      cl38908
      Location:23107
      BTB_POZ; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain superfamily
    3. XM_006496135.4XP_006496198.1  BTB/POZ domain-containing protein KCTD18 isoform X1

      See identical proteins and their annotated locations for XP_006496198.1

      UniProtKB/TrEMBL
      E0CZ26
      Conserved Domains (2) summary
      cd18372
      Location:23123
      BTB_POZ_KCTD18; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in potassium channel tetramerization domain-containing protein 18 (KCTD18)
      pfam17669
      Location:339414
      DUF5529; Family of unknown function (DUF5529)
    4. XM_017321677.3XP_017177166.1  BTB/POZ domain-containing protein KCTD18 isoform X4

    5. XM_017321676.3XP_017177165.1  BTB/POZ domain-containing protein KCTD18 isoform X2

      Conserved Domains (1) summary
      pfam17669
      Location:218293
      DUF5529; Family of unknown function (DUF5529)
    6. XM_036152329.1XP_036008222.1  BTB/POZ domain-containing protein KCTD18 isoform X4

      Conserved Domains (1) summary
      pfam15323
      Location:66174
      Ashwin; Developmental protein

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_030211.3: Suppressed sequence

      Description
      NM_030211.3: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein, and the transcript appears to retain intronic sequence at its 3' end.
    Support Center