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    Bnc2 basonuclin zinc finger protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 242509, updated on 12-May-2024

    Summary

    Official Symbol
    Bnc2provided by MGI
    Official Full Name
    basonuclin zinc finger protein 2provided by MGI
    Primary source
    MGI:MGI:2443805
    See related
    Ensembl:ENSMUSG00000028487 AllianceGenome:MGI:2443805
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    5031434M05Rik; 8430420F16Rik
    Summary
    Enables DNA binding activity. Acts upstream of or within several processes, including endochondral bone growth; roof of mouth development; and tongue development. Located in nucleus. Is expressed in several structures, including genitourinary system; jaw; nervous system; nose; and skin. Orthologous to human BNC2 (basonuclin 2). [provided by Alliance of Genome Resources, Apr 2022]
    Annotation information
    Annotation category: partial on reference assembly
    Expression
    Biased expression in limb E14.5 (RPKM 4.5), bladder adult (RPKM 2.8) and 13 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Bnc2 in Genome Data Viewer
    Location:
    4 C3- C4; 4 39.76 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (84185041..84593236, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (84266804..84676029, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 42310 Neighboring gene predicted gene, 33597 Neighboring gene STARR-seq mESC enhancer starr_10655 Neighboring gene STARR-seq mESC enhancer starr_10656 Neighboring gene STARR-seq mESC enhancer starr_10659 Neighboring gene STARR-seq mESC enhancer starr_10660 Neighboring gene STARR-seq mESC enhancer starr_10664 Neighboring gene STARR-seq mESC enhancer starr_10666 Neighboring gene STARR-seq mESC enhancer starr_10669 Neighboring gene serine incorporator 3 pseudogene Neighboring gene predicted gene 12415

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 
    • Gene trapped (1) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC124423, MGC124424

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables rDNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    zinc finger protein basonuclin-2
    Names
    basonuclin 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001369081.2NP_001356010.1  zinc finger protein basonuclin-2 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AL772137, AL772261, AL805919, BX004826
      UniProtKB/Swiss-Prot
      H3BIU0, Q6T3A4, Q8BMQ3
      Conserved Domains (2) summary
      sd00017
      Location:10441065
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:842863
      ZF_C2H2; C2H2 Zn finger [structural motif]
    2. NM_001369082.2NP_001356011.1  zinc finger protein basonuclin-2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL772137, AL772261, AL805919, BX004826
      UniProtKB/TrEMBL
      Q2TBA5
      Conserved Domains (2) summary
      sd00017
      Location:977998
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:775796
      ZF_C2H2; C2H2 Zn finger [structural motif]
    3. NM_001369083.2NP_001356012.1  zinc finger protein basonuclin-2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL772137, AL772261, AL805919, BX004826
      Consensus CDS
      CCDS89773.1
      UniProtKB/Swiss-Prot
      H3BIU0, Q6T3A4, Q8BMQ3
      UniProtKB/TrEMBL
      H3BIU2
      Related
      ENSMUSP00000102816.3, ENSMUST00000107198.9
      Conserved Domains (2) summary
      sd00017
      Location:10371058
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:835856
      ZF_C2H2; C2H2 Zn finger [structural motif]
    4. NM_001369084.2NP_001356013.1  zinc finger protein basonuclin-2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL772137, AL772261, AL805919, BX004826
      UniProtKB/TrEMBL
      Q2TBA4, Q2TBA5
      Conserved Domains (1) summary
      sd00017
      Location:959980
      ZF_C2H2; C2H2 Zn finger [structural motif]
    5. NM_172870.6NP_766458.3  zinc finger protein basonuclin-2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL772137, AL772261, AL805919, BX004826
      Consensus CDS
      CCDS18301.2
      UniProtKB/TrEMBL
      Q2TBA5
      Related
      ENSMUSP00000135375.2, ENSMUST00000176691.8
      Conserved Domains (1) summary
      sd00017
      Location:970991
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      84185041..84593236 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)