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    Gtf3c1 general transcription factor III C 1 [ Mus musculus (house mouse) ]

    Gene ID: 233863, updated on 31-Jan-2019

    Summary

    Official Symbol
    Gtf3c1provided by MGI
    Official Full Name
    general transcription factor III C 1provided by MGI
    Primary source
    MGI:MGI:107887
    See related
    Ensembl:ENSMUSG00000032777
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Ubiquitous expression in ovary adult (RPKM 33.4), thymus adult (RPKM 24.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Gtf3c1 in Genome Data Viewer
    Location:
    7 F3; 7 69.01 cM
    Exon count:
    37
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (125640954..125707688, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (132784468..132851202, complement)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene interleukin 4 receptor, alpha Neighboring gene interleukin 21 receptor Neighboring gene RIKEN cDNA D430042O09 gene Neighboring gene GSG1-like

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Transgenic (1) 
    • Endonuclease-mediated (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to RNA polymerase III general transcription initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RNA polymerase III type 1 promoter sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RNA polymerase III type 2 promoter sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    5S class rRNA transcription by RNA polymerase III IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription initiation from RNA polymerase III promoter IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    ribonucleoprotein complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription factor TFIIIC complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription factor TFIIIC complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    general transcription factor 3C polypeptide 1
    Names
    TF3C-alpha
    TFIIIC 220 kDa subunit
    TFIIIC box B-binding subunit
    TFIIIC220
    transcription factor IIIC 220 kDa subunit
    transcription factor IIIC subunit alpha

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_207239.1NP_997122.1  general transcription factor 3C polypeptide 1

      See identical proteins and their annotated locations for NP_997122.1

      Status: PROVISIONAL

      Source sequence(s)
      BC067041
      Consensus CDS
      CCDS40122.1
      UniProtKB/Swiss-Prot
      Q8K284
      Related
      ENSMUSP00000056719.7, ENSMUST00000055506.8
      Conserved Domains (1) summary
      pfam04182
      Location:174250
      B-block_TFIIIC; B-block binding subunit of TFIIIC

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      125640954..125707688 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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