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    Amn1 antagonist of mitotic exit network 1 [ Mus musculus (house mouse) ]

    Gene ID: 232566, updated on 31-Jan-2019

    Summary

    Official Symbol
    Amn1provided by MGI
    Official Full Name
    antagonist of mitotic exit network 1provided by MGI
    Primary source
    MGI:MGI:2442933
    See related
    Ensembl:ENSMUSG00000068250
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    A230083D09; 5830467E07Rik; C730024G19Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 5.0), CNS E18 (RPKM 4.2) and 28 other tissues See more
    Orthologs

    Genomic context

    See Amn1 in Genome Data Viewer
    Location:
    6; 6 G3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (149157261..149188771, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (149106099..149137234, complement)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene DENN/MADD domain containing 5B Neighboring gene SEH1-like (S. cerevisiae pseudogene Neighboring gene electron transfer flavoprotein beta subunit lysine methyltransferase Neighboring gene retroelement silencing factor 1 Neighboring gene predicted gene, 38930

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    SCF ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    protein AMN1 homolog
    Names
    antagonist of mitotic exit network 1 homolog

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001113424.1NP_001106895.1  protein AMN1 homolog isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC128664, AC132412
      Consensus CDS
      CCDS51961.1
      UniProtKB/TrEMBL
      B8JKV0
      Related
      ENSMUSP00000107160.1, ENSMUST00000111535.7
      Conserved Domains (2) summary
      cd09293
      Location:37257
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:6386
      LRR_AMN1; leucine-rich repeat [structural motif]
    2. NM_001356344.1NP_001343273.1  protein AMN1 homolog isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC128664, AC132412
      Conserved Domains (2) summary
      sd00034
      Location:2043
      LRR_AMN1; leucine-rich repeat [structural motif]
      cl28166
      Location:1214
      AMN1; Antagonist of mitotic exit network protein 1

    RNA

    1. NR_153963.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice site and lacks two exons in the 5' region compared to variant 1. This variant is represented as non-coding because it lacks a large portion of the coding sequence found in variant 1.
      Source sequence(s)
      AC128664, AK038995

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      149157261..149188771 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006507045.3XP_006507108.1  protein AMN1 homolog isoform X1

      See identical proteins and their annotated locations for XP_006507108.1

      Conserved Domains (2) summary
      cd09293
      Location:29249
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:5578
      LRR_AMN1; leucine-rich repeat [structural motif]
    2. XM_006507046.3XP_006507109.1  protein AMN1 homolog isoform X2

      UniProtKB/TrEMBL
      B8JKU8
      Related
      ENSMUSP00000092957.3, ENSMUST00000095319.9
      Conserved Domains (2) summary
      sd00034
      Location:2043
      LRR_AMN1; leucine-rich repeat [structural motif]
      cl28166
      Location:1214
      AMN1; Antagonist of mitotic exit network protein 1
    3. XM_006507047.3XP_006507110.1  protein AMN1 homolog isoform X3

      See identical proteins and their annotated locations for XP_006507110.1

      Conserved Domains (2) summary
      cd09293
      Location:18178
      AMN1; Antagonist of mitotic exit network protein 1
      sd00034
      Location:3863
      LRR_AMN1; leucine-rich repeat [structural motif]

    Reference GRCm38.p4 NOD/ShiLtJ

    Genomic

    1. NT_166305.2 Reference GRCm38.p4 NOD/ShiLtJ

      Range
      5545527..5576663 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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