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    Sec24c Sec24 related gene family, member C (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 218811, updated on 23-Jun-2021

    Summary

    Official Symbol
    Sec24cprovided by MGI
    Official Full Name
    Sec24 related gene family, member C (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1919746
    See related
    Ensembl:ENSMUSG00000039367
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA0079; 2610204K03Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 52.7), large intestine adult (RPKM 44.2) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Sec24c in Genome Data Viewer
    Location:
    14; 14 A3
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (20722709..20744920)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (20674285..20694852)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (21493543..21514072)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene myozenin 1 Neighboring gene synaptopodin 2-like Neighboring gene microRNA 6946 Neighboring gene fucosyltransferase 11 Neighboring gene predicted gene, 25328

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables SNARE binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables SNARE binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of COPII vesicle coat IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of COPII vesicle coat ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endoplasmic reticulum exit site IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    protein transport protein Sec24C

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001168273.1NP_001161745.1  protein transport protein Sec24C isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame segment and contains an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AK036519, AK122199
      Consensus CDS
      CCDS88586.1
      UniProtKB/TrEMBL
      A0A286YDI8, Q80U83
      Related
      ENSMUSP00000153434.2, ENSMUST00000223751.2
      Conserved Domains (7) summary
      COG5028
      Location:801016
      COG5028; Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
      cd01479
      Location:425684
      Sec24-like; Sec24-like: Protein and membrane traffic in eukaryotes is mediated by at least in part by the budding and fusion of intracellular transport vesicles that selectively carry cargo proteins and lipids from donor to acceptor organelles. The two main classes ...
      pfam00626
      Location:890962
      Gelsolin; Gelsolin repeat
      pfam04810
      Location:348385
      zf-Sec23_Sec24; Sec23/Sec24 zinc finger
      pfam04815
      Location:773869
      Sec23_helical; Sec23/Sec24 helical domain
      pfam08033
      Location:674757
      Sec23_BS; Sec23/Sec24 beta-sandwich domain
      pfam12764
      Location:11105
      Gly-rich_Ago1; Glycine-rich region of argonaut
    2. NM_172596.2NP_766184.2  protein transport protein Sec24C isoform 1

      See identical proteins and their annotated locations for NP_766184.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK036519, AK122199
      Consensus CDS
      CCDS26850.1
      UniProtKB/TrEMBL
      G3X972, Q80U83
      Related
      ENSMUSP00000045955.9, ENSMUST00000048657.10
      Conserved Domains (2) summary
      PHA03377
      Location:21224
      PHA03377; EBNA-3C; Provisional
      COG5028
      Location:1811092
      COG5028; Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      20722709..20744920
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006518813.2XP_006518876.1  protein transport protein Sec24C isoform X1

      See identical proteins and their annotated locations for XP_006518876.1

      Conserved Domains (2) summary
      COG5028
      Location:1811117
      COG5028; Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
      pfam15449
      Location:12235
      Retinal; Retinal protein
    2. XM_006518817.2XP_006518880.1  protein transport protein Sec24C isoform X2

      Conserved Domains (2) summary
      COG5028
      Location:1811115
      COG5028; Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
      pfam15449
      Location:12235
      Retinal; Retinal protein
    3. XM_036158551.1XP_036014444.1  protein transport protein Sec24C isoform X2

      Conserved Domains (2) summary
      COG5028
      Location:1811115
      COG5028; Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
      pfam15449
      Location:12235
      Retinal; Retinal protein
    4. XM_030247745.2XP_030103605.1  protein transport protein Sec24C isoform X4

      Conserved Domains (2) summary
      PHA03377
      Location:21224
      PHA03377; EBNA-3C; Provisional
      COG5028
      Location:1811092
      COG5028; Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
    5. XM_006518816.3XP_006518879.1  protein transport protein Sec24C isoform X1

      See identical proteins and their annotated locations for XP_006518879.1

      Conserved Domains (2) summary
      COG5028
      Location:1811117
      COG5028; Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
      pfam15449
      Location:12235
      Retinal; Retinal protein
    6. XM_006518815.3XP_006518878.1  protein transport protein Sec24C isoform X1

      See identical proteins and their annotated locations for XP_006518878.1

      Conserved Domains (2) summary
      COG5028
      Location:1811117
      COG5028; Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
      pfam15449
      Location:12235
      Retinal; Retinal protein
    7. XM_030247743.2XP_030103603.1  protein transport protein Sec24C isoform X3

      Conserved Domains (2) summary
      COG5028
      Location:1811094
      COG5028; Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
      pfam15449
      Location:12235
      Retinal; Retinal protein
    8. XM_036158550.1XP_036014443.1  protein transport protein Sec24C isoform X1

      Conserved Domains (2) summary
      COG5028
      Location:1811117
      COG5028; Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
      pfam15449
      Location:12235
      Retinal; Retinal protein
    9. XM_036158552.1XP_036014445.1  protein transport protein Sec24C isoform X3

      Conserved Domains (2) summary
      COG5028
      Location:1811094
      COG5028; Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
      pfam15449
      Location:12235
      Retinal; Retinal protein
    10. XM_006518818.3XP_006518881.1  protein transport protein Sec24C isoform X3

      Conserved Domains (2) summary
      COG5028
      Location:1811094
      COG5028; Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
      pfam15449
      Location:12235
      Retinal; Retinal protein
    11. XM_030247744.2XP_030103604.1  protein transport protein Sec24C isoform X3

      Conserved Domains (2) summary
      COG5028
      Location:1811094
      COG5028; Vesicle coat complex COPII, subunit SEC24/subunit SFB2/subunit SFB3 [Intracellular trafficking and secretion]
      pfam15449
      Location:12235
      Retinal; Retinal protein
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