Format

Send to:

Choose Destination
    • Showing Current items.

    Mis18bp1 MIS18 binding protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 217653, updated on 23-Jun-2021

    Summary

    Official Symbol
    Mis18bp1provided by MGI
    Official Full Name
    MIS18 binding protein 1provided by MGI
    Primary source
    MGI:MGI:2145099
    See related
    Ensembl:ENSMUSG00000047534
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Knl2; C79407; mKIAA1903; 6720403H11
    Expression
    Biased expression in CNS E11.5 (RPKM 12.0), liver E14 (RPKM 9.4) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Mis18bp1 in Genome Data Viewer
    Location:
    12; 12 C1
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (65179508..65219354, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (65132734..65172581, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (66233721..66273567, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene pre-mRNA processing factor 39 Neighboring gene FK506 binding protein 3 Neighboring gene Fanconi anemia, complementation group M Neighboring gene predicted gene, 31063 Neighboring gene WD repeat domain 20, retrogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA1903

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    mis18-binding protein 1
    Names
    kinetochore-associated protein KNL-2 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172578.2NP_766166.2  mis18-binding protein 1

      See identical proteins and their annotated locations for NP_766166.2

      Status: PROVISIONAL

      Source sequence(s)
      BC052175
      Consensus CDS
      CCDS25942.1
      UniProtKB/Swiss-Prot
      Q80WQ8
      Related
      ENSMUSP00000052109.9, ENSMUST00000052201.9
      Conserved Domains (3) summary
      smart00717
      Location:744788
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:745788
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam09133
      Location:338425
      SANTA; SANTA (SANT Associated)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      65179508..65219354 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036157309.1XP_036013202.1  mis18-binding protein 1 isoform X1

      Conserved Domains (1) summary
      cd00167
      Location:143186
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    Support Center