Format

Send to:

Choose Destination
    • Showing Current items.

    Zfp598 zinc finger protein 598 [ Mus musculus (house mouse) ]

    Gene ID: 213753, updated on 31-Jan-2019

    Summary

    Official Symbol
    Zfp598provided by MGI
    Official Full Name
    zinc finger protein 598provided by MGI
    Primary source
    MGI:MGI:2670965
    See related
    Ensembl:ENSMUSG00000041130
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ntrap; Znf598; BC023040
    Expression
    Ubiquitous expression in colon adult (RPKM 52.8), ovary adult (RPKM 51.1) and 28 other tissues See more
    Orthologs

    Genomic context

    See Zfp598 in Genome Data Viewer
    Location:
    17; 17 A3.3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 17 NC_000083.6 (24669693..24682016)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (24806697..24818961)

    Chromosome 17 - NC_000083.6Genomic Context describing neighboring genes Neighboring gene solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 Neighboring gene neuropeptide W Neighboring gene synaptogyrin 3 Neighboring gene growth factor, augmenter of liver regeneration

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    ribosome binding ISO
    Inferred from Sequence Orthology
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    ubiquitin protein ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    protein monoubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of translation IEA
    Inferred from Electronic Annotation
    more info
     
    rescue of stalled ribosome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase ZNF598; zinc finger protein 598
    NP_898972.1
    XP_006524062.1
    XP_006524063.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001348231.1NP_001335160.1  E3 ubiquitin-protein ligase ZNF598 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AC154566, BC050859, BQ180106, CF537189
      UniProtKB/Swiss-Prot
      Q80YR4
      Conserved Domains (2) summary
      COG5236
      Location:27336
      COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
      cl26464
      Location:366675
      Atrophin-1; Atrophin-1 family
    2. NM_183149.2NP_898972.1  E3 ubiquitin-protein ligase ZNF598 isoform 1

      See identical proteins and their annotated locations for NP_898972.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC154566, BC050859, CF537189
      Consensus CDS
      CCDS28490.1
      UniProtKB/Swiss-Prot
      Q80YR4
      Related
      ENSMUSP00000157172.1, ENSMUST00000234956.1
      Conserved Domains (1) summary
      COG5236
      Location:27326
      COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000083.6 Reference GRCm38.p4 C57BL/6J

      Range
      24669693..24682016
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006523999.1XP_006524062.1  zinc finger protein 598 isoform X1

      UniProtKB/Swiss-Prot
      Q80YR4
      Related
      ENSMUSP00000038367.6, ENSMUST00000047179.6
      Conserved Domains (2) summary
      COG5236
      Location:27336
      COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
      cl26464
      Location:366675
      Atrophin-1; Atrophin-1 family
    2. XM_006524000.1XP_006524063.1  zinc finger protein 598 isoform X2

      Conserved Domains (2) summary
      PHA03247
      Location:198507
      PHA03247; large tegument protein UL36; Provisional
      COG5236
      Location:11155
      COG5236; Uncharacterized conserved protein, contains RING Zn-finger [General function prediction only]
    Support Center