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    Ncor1 nuclear receptor co-repressor 1 [ Mus musculus (house mouse) ]

    Gene ID: 20185, updated on 18-Nov-2018

    Summary

    Official Symbol
    Ncor1provided by MGI
    Official Full Name
    nuclear receptor co-repressor 1provided by MGI
    Primary source
    MGI:MGI:1349717
    See related
    Ensembl:ENSMUSG00000018501 Vega:OTTMUSG00000005855
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    N-CoR; RIP13; Rxrip13; mKIAA1047; 5730405M06Rik; A230020K14Rik
    Expression
    Ubiquitous expression in thymus adult (RPKM 15.4), CNS E14 (RPKM 13.2) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ncor1 in Genome Data Viewer
    Location:
    11; 11 B2
    Exon count:
    50
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (62315663..62458703, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (62130192..62270834, complement)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene adenosine A2b receptor Neighboring gene zinc finger SWIM-type containing 7 Neighboring gene tetratricopeptide repeat domain 19 Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class L Neighboring gene centromere protein V Neighboring gene predicted gene 12279

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    RNA polymerase II activating transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    RNA polymerase II regulatory region DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    RNA polymerase II regulatory region DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    estrogen receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    histone deacetylase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone deacetylase binding ISO
    Inferred from Sequence Orthology
    more info
     
    histone deacetylase regulator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    histone deacetylase regulator activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nuclear hormone receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear hormone receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    peroxisome proliferator activated receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein domain specific binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    retinoic acid receptor binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    retinoic acid receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    retinoid X receptor binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    retinoid X receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    thyroid hormone receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    thyroid hormone receptor binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    thyroid hormone receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription corepressor activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    transcription corepressor activity ISO
    Inferred from Sequence Orthology
    more info
     
    transcription regulatory region DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cellular response to Thyroglobulin triiodothyronine IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    cholesterol homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    circadian regulation of gene expression IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    definitive erythrocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of JNK cascade ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of androgen receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of phosphatidylinositol 3-kinase signaling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of production of miRNAs involved in gene silencing by miRNA ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    negative regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    negative regulation of transcription, DNA-templated IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of histone deacetylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of multicellular organism growth IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of thyroid hormone mediated signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    spindle assembly ISO
    Inferred from Sequence Orthology
    more info
     
    thalamus development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    colocalizes_with Sin3 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with Sin3 complex ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    histone deacetylase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    histone deacetylase complex ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic spindle ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    transcription factor complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcriptional repressor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcriptional repressor complex IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    transcriptional repressor complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    nuclear receptor corepressor 1
    Names
    N-CoR1
    retinoid X receptor-interacting protein 13

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001252313.1NP_001239242.1  nuclear receptor corepressor 1 isoform 1

      See identical proteins and their annotated locations for NP_001239242.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AL596110, BX248411
      Consensus CDS
      CCDS56781.1
      UniProtKB/TrEMBL
      Q5RIM6
      Related
      ENSMUSP00000098627.3, ENSMUST00000101066.9
      Conserved Domains (4) summary
      smart00717
      Location:627672
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam05285
      Location:678760
      SDA1; SDA1
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
    2. NM_011308.3NP_035438.3  nuclear receptor corepressor 1 isoform 2

      See identical proteins and their annotated locations for NP_035438.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has multiple differences in the coding region but maintains the reading frame, compared to variant 1. The resulting isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AB093281, AK077420, BC086657, BU504661
      UniProtKB/TrEMBL
      Q5PRE9, Q8BK32, Q8CHB6
      Related
      ENSMUSP00000098628.3, OTTMUSP00000047847, ENSMUST00000101067.9, OTTMUST00000087854
      Conserved Domains (3) summary
      smart00717
      Location:627672
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
    3. NM_177229.3NP_796203.1  nuclear receptor corepressor 1 isoform 3

      See identical proteins and their annotated locations for NP_796203.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks multiple exons and includes an alternate 3' terminal exon, compared to variant 1. The resulting isoform (3) is much shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AK035813, AK077420, BB140234, BB673294
      Consensus CDS
      CCDS56782.1
      UniProtKB/TrEMBL
      Q8BK32
      Related
      ENSMUSP00000068974.4, OTTMUSP00000006061, ENSMUST00000069456.10, OTTMUST00000013030
      Conserved Domains (1) summary
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      62315663..62458703 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532628.3XP_006532691.1  nuclear receptor corepressor 1 isoform X46

      Conserved Domains (4) summary
      smart00717
      Location:627672
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam05285
      Location:678760
      SDA1; SDA1
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
    2. XM_017314387.1XP_017169876.1  nuclear receptor corepressor 1 isoform X41

    3. XM_017314369.1XP_017169858.1  nuclear receptor corepressor 1 isoform X17

    4. XM_017314389.1XP_017169878.1  nuclear receptor corepressor 1 isoform X43

    5. XM_017314388.1XP_017169877.1  nuclear receptor corepressor 1 isoform X42

    6. XM_017314367.1XP_017169856.1  nuclear receptor corepressor 1 isoform X15

    7. XM_017314356.1XP_017169845.1  nuclear receptor corepressor 1 isoform X1

      Conserved Domains (4) summary
      smart00717
      Location:637682
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:637680
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      pfam16001
      Location:691916
      DUF4775; Domain of unknown function (DUF4775)
    8. XM_006532624.3XP_006532687.1  nuclear receptor corepressor 1 isoform X29

      See identical proteins and their annotated locations for XP_006532687.1

      UniProtKB/TrEMBL
      Q5RIM6
      Related
      ENSMUSP00000018645.6, OTTMUSP00000006054, ENSMUST00000018645.12, OTTMUST00000013021
      Conserved Domains (4) summary
      smart00717
      Location:627672
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam05285
      Location:678760
      SDA1; SDA1
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
    9. XM_017314379.1XP_017169868.1  nuclear receptor corepressor 1 isoform X31

    10. XM_017314368.1XP_017169857.1  nuclear receptor corepressor 1 isoform X16

    11. XM_017314364.1XP_017169853.1  nuclear receptor corepressor 1 isoform X11

      Conserved Domains (4) summary
      smart00717
      Location:627672
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      pfam16001
      Location:681906
      DUF4775; Domain of unknown function (DUF4775)
    12. XM_017314357.1XP_017169846.1  nuclear receptor corepressor 1 isoform X1

      Conserved Domains (4) summary
      smart00717
      Location:637682
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:637680
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      pfam16001
      Location:691916
      DUF4775; Domain of unknown function (DUF4775)
    13. XM_017314363.1XP_017169852.1  nuclear receptor corepressor 1 isoform X10

    14. XM_017314358.1XP_017169847.1  nuclear receptor corepressor 1 isoform X1

      Conserved Domains (4) summary
      smart00717
      Location:637682
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:637680
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      pfam16001
      Location:691916
      DUF4775; Domain of unknown function (DUF4775)
    15. XM_006532625.3XP_006532688.1  nuclear receptor corepressor 1 isoform X30

      Conserved Domains (3) summary
      smart00717
      Location:627672
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
    16. XM_006532623.3XP_006532686.1  nuclear receptor corepressor 1 isoform X28

      Conserved Domains (4) summary
      smart00717
      Location:627672
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam05285
      Location:678760
      SDA1; SDA1
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
    17. XM_006532627.3XP_006532690.1  nuclear receptor corepressor 1 isoform X39

      Conserved Domains (3) summary
      smart00717
      Location:627672
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
    18. XM_006532619.3XP_006532682.1  nuclear receptor corepressor 1 isoform X11

      Conserved Domains (4) summary
      smart00717
      Location:627672
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      pfam16001
      Location:681906
      DUF4775; Domain of unknown function (DUF4775)
    19. XM_017314362.1XP_017169851.1  nuclear receptor corepressor 1 isoform X10

    20. XM_017314391.1XP_017169880.1  nuclear receptor corepressor 1 isoform X45

    21. XM_017314378.1XP_017169867.1  nuclear receptor corepressor 1 isoform X27

    22. XM_006532618.3XP_006532681.1  nuclear receptor corepressor 1 isoform X9

      Conserved Domains (4) summary
      smart00717
      Location:636681
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:636679
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam05285
      Location:687769
      SDA1; SDA1
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
    23. XM_006532620.3XP_006532683.1  nuclear receptor corepressor 1 isoform X13

      Conserved Domains (4) summary
      smart00717
      Location:636681
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:636679
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      pfam16001
      Location:690899
      DUF4775; Domain of unknown function (DUF4775)
    24. XM_017314374.1XP_017169863.1  nuclear receptor corepressor 1 isoform X23

    25. XM_006532613.3XP_006532676.1  nuclear receptor corepressor 1 isoform X2

      Conserved Domains (4) summary
      smart00717
      Location:636681
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:636679
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      pfam16001
      Location:690915
      DUF4775; Domain of unknown function (DUF4775)
    26. XM_017314377.1XP_017169866.1  nuclear receptor corepressor 1 isoform X26

    27. XM_017314386.1XP_017169875.1  nuclear receptor corepressor 1 isoform X40

    28. XM_017314366.1XP_017169855.1  nuclear receptor corepressor 1 isoform X14

    29. XM_017314382.1XP_017169871.1  nuclear receptor corepressor 1 isoform X34

    30. XM_017314361.1XP_017169850.1  nuclear receptor corepressor 1 isoform X8

    31. XM_017314372.1XP_017169861.1  nuclear receptor corepressor 1 isoform X21

    32. XM_017314365.1XP_017169854.1  nuclear receptor corepressor 1 isoform X12

    33. XM_017314380.1XP_017169869.1  nuclear receptor corepressor 1 isoform X32

    34. XM_017314375.1XP_017169864.1  nuclear receptor corepressor 1 isoform X24

    35. XM_017314373.1XP_017169862.1  nuclear receptor corepressor 1 isoform X22

    36. XM_017314371.1XP_017169860.1  nuclear receptor corepressor 1 isoform X20

    37. XM_017314360.1XP_017169849.1  nuclear receptor corepressor 1 isoform X7

    38. XM_006532621.3XP_006532684.1  nuclear receptor corepressor 1 isoform X19

      Conserved Domains (4) summary
      smart00717
      Location:637682
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:637680
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      pfam16001
      Location:691916
      DUF4775; Domain of unknown function (DUF4775)
    39. XM_017314370.1XP_017169859.1  nuclear receptor corepressor 1 isoform X18

    40. XM_017314385.1XP_017169874.1  nuclear receptor corepressor 1 isoform X38

    41. XM_017314359.1XP_017169848.1  nuclear receptor corepressor 1 isoform X6

    42. XM_006532616.3XP_006532679.1  nuclear receptor corepressor 1 isoform X4

      Conserved Domains (4) summary
      smart00717
      Location:637682
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:637680
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      pfam16001
      Location:691916
      DUF4775; Domain of unknown function (DUF4775)
    43. XM_006532626.3XP_006532689.1  nuclear receptor corepressor 1 isoform X37

      Conserved Domains (4) summary
      smart00717
      Location:637682
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:637680
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      pfam16001
      Location:691916
      DUF4775; Domain of unknown function (DUF4775)
    44. XM_017314384.1XP_017169873.1  nuclear receptor corepressor 1 isoform X36

    45. XM_006532614.3XP_006532677.1  nuclear receptor corepressor 1 isoform X3

      Conserved Domains (4) summary
      smart00717
      Location:637682
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:637680
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      pfam16001
      Location:691916
      DUF4775; Domain of unknown function (DUF4775)
    46. XM_017314383.1XP_017169872.1  nuclear receptor corepressor 1 isoform X35

    47. XM_017314381.1XP_017169870.1  nuclear receptor corepressor 1 isoform X33

    48. XM_017314376.1XP_017169865.1  nuclear receptor corepressor 1 isoform X25

    49. XM_017314390.1XP_017169879.1  nuclear receptor corepressor 1 isoform X44

    50. XM_006532615.3XP_006532678.1  nuclear receptor corepressor 1 isoform X5

      Conserved Domains (4) summary
      smart00717
      Location:637682
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:637680
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:153238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      pfam16001
      Location:691916
      DUF4775; Domain of unknown function (DUF4775)
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