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NCOR1 nuclear receptor corepressor 1 [ Homo sapiens (human) ]

Gene ID: 9611, updated on 24-Nov-2020

Summary

Official Symbol
NCOR1provided by HGNC
Official Full Name
nuclear receptor corepressor 1provided by HGNC
Primary source
HGNC:HGNC:7672
See related
Ensembl:ENSG00000141027 MIM:600849
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
N-CoR; TRAC1; N-CoR1; hN-CoR; PPP1R109
Summary
This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010]
Expression
Ubiquitous expression in thyroid (RPKM 10.9), colon (RPKM 10.7) and 25 other tissues See more
Orthologs

Genomic context

See NCOR1 in Genome Data Viewer
Location:
17p12-p11.2
Exon count:
54
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (16029157..16216475, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (15933408..16118874, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene adenosine A2b receptor Neighboring gene zinc finger SWIM-type containing 7 Neighboring gene tetratricopeptide repeat domain 19 Neighboring gene ribosomal protein lateral stalk subunit P1 pseudogene 11 Neighboring gene ribosomal protein L22 pseudogene 21 Neighboring gene RNA, U6 small nuclear 314, pseudogene Neighboring gene RNA, U6 small nuclear 862, pseudogene Neighboring gene small nucleolar RNA, C/D box 163 Neighboring gene RNA, 7SL, cytoplasmic 442, pseudogene Neighboring gene phosphatidylinositol glycan anchor biosynthesis class L Neighboring gene Sharpr-MPRA regulatory region 12459 Neighboring gene microRNA 1288

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Vif vif HIV-1 Vif is identified to have a physical interaction with nuclear receptor corepressor 1 (NCOR1) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses PubMed

Go to the HIV-1, Human Interaction Database

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA1047, MGC104216

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA polymerase II activating transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
histone deacetylase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histone deacetylase binding IPI
Inferred from Physical Interaction
more info
PubMed 
nuclear hormone receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
nuclear hormone receptor binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
thyroid hormone receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription corepressor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription corepressor activity IDA
Inferred from Direct Assay
more info
PubMed 
transcription corepressor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
transcription regulatory region sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
colocalizes_with Sin3 complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
colocalizes_with Sin3 complex IDA
Inferred from Direct Assay
more info
PubMed 
chromatin IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
chromatin IDA
Inferred from Direct Assay
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
 
histone deacetylase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
histone deacetylase complex IDA
Inferred from Direct Assay
more info
PubMed 
membrane HDA PubMed 
mitotic spindle IDA
Inferred from Direct Assay
more info
PubMed 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleoplasm TAS
Traceable Author Statement
more info
 
nucleus IC
Inferred by Curator
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
transcription repressor complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
transcription repressor complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
nuclear receptor corepressor 1
Names
protein phosphatase 1, regulatory subunit 109
thyroid hormone- and retinoic acid receptor-associated corepressor 1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_047111.1 RefSeqGene

    Range
    6213..192590
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001190438.1NP_001177367.1  nuclear receptor corepressor 1 isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) has multiple differences compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AF303586, BC056862
    Consensus CDS
    CCDS54094.1
    UniProtKB/Swiss-Prot
    O75376
    UniProtKB/TrEMBL
    Q6PGR4
    Related
    ENSP00000379189.1, ENST00000395848.5
    Conserved Domains (4) summary
    pfam05887
    Location:596677
    Trypan_PARP; Procyclic acidic repetitive protein (PARP)
    smart00717
    Location:518563
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:518561
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:41128
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  2. NM_001190440.1NP_001177369.1  nuclear receptor corepressor 1 isoform 3

    See identical proteins and their annotated locations for NP_001177369.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 3, which is shorter than isoform 1.
    Source sequence(s)
    AB028970, AC002553, AW015698, BC056862
    Consensus CDS
    CCDS54095.1
    UniProtKB/Swiss-Prot
    O75376
    UniProtKB/TrEMBL
    Q6PGR4
    Related
    ENSP00000379192.1, ENST00000395851.5
    Conserved Domains (4) summary
    smart00717
    Location:627672
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:627670
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam05285
    Location:678760
    SDA1; SDA1
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  3. NM_006311.4NP_006302.2  nuclear receptor corepressor 1 isoform 1

    See identical proteins and their annotated locations for NP_006302.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AC002553, AF044209, AW015698, BJ995810
    Consensus CDS
    CCDS11175.1
    UniProtKB/Swiss-Prot
    O75376
    UniProtKB/TrEMBL
    A0A024RD47
    Related
    ENSP00000268712.2, ENST00000268712.8
    Conserved Domains (3) summary
    smart00717
    Location:627672
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:627670
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    16029157..16216475 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011524086.3XP_011522388.1  nuclear receptor corepressor 1 isoform X16

    See identical proteins and their annotated locations for XP_011522388.1

    UniProtKB/Swiss-Prot
    O75376
    Conserved Domains (4) summary
    smart00717
    Location:627672
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:627670
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam05285
    Location:678760
    SDA1; SDA1
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  2. XM_017025415.2XP_016880904.1  nuclear receptor corepressor 1 isoform X9

  3. XM_017025418.2XP_016880907.1  nuclear receptor corepressor 1 isoform X14

  4. XM_011524084.3XP_011522386.1  nuclear receptor corepressor 1 isoform X3

    Conserved Domains (4) summary
    smart00717
    Location:637682
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:637680
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam05285
    Location:688770
    SDA1; SDA1
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  5. XM_006721603.4XP_006721666.1  nuclear receptor corepressor 1 isoform X6

    Conserved Domains (4) summary
    smart00717
    Location:637682
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:637680
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam05285
    Location:688770
    SDA1; SDA1
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  6. XM_017025406.2XP_016880895.1  nuclear receptor corepressor 1 isoform X4

    Conserved Domains (3) summary
    cd00167
    Location:628671
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:684858
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  7. XM_011524083.3XP_011522385.1  nuclear receptor corepressor 1 isoform X1

    See identical proteins and their annotated locations for XP_011522385.1

    Conserved Domains (4) summary
    smart00717
    Location:637682
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:637680
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam05285
    Location:688770
    SDA1; SDA1
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  8. XM_017025411.2XP_016880900.1  nuclear receptor corepressor 1 isoform X5

    Conserved Domains (3) summary
    cd00167
    Location:627670
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:683857
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  9. XM_017025397.2XP_016880886.1  nuclear receptor corepressor 1 isoform X1

    Conserved Domains (4) summary
    smart00717
    Location:637682
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:637680
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam05285
    Location:688770
    SDA1; SDA1
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  10. XM_017025401.2XP_016880890.1  nuclear receptor corepressor 1 isoform X2

    Conserved Domains (3) summary
    cd00167
    Location:636679
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:692866
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  11. XM_017025400.2XP_016880889.1  nuclear receptor corepressor 1 isoform X2

    Conserved Domains (3) summary
    cd00167
    Location:636679
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:692866
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  12. XM_017025396.2XP_016880885.1  nuclear receptor corepressor 1 isoform X1

    Conserved Domains (4) summary
    smart00717
    Location:637682
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:637680
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam05285
    Location:688770
    SDA1; SDA1
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  13. XM_006721601.4XP_006721664.1  nuclear receptor corepressor 1 isoform X1

    See identical proteins and their annotated locations for XP_006721664.1

    Conserved Domains (4) summary
    smart00717
    Location:637682
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:637680
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam05285
    Location:688770
    SDA1; SDA1
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  14. XM_017025416.2XP_016880905.1  nuclear receptor corepressor 1 isoform X10

    Conserved Domains (4) summary
    smart00717
    Location:627672
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:627670
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam05285
    Location:678760
    SDA1; SDA1
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  15. XM_017025409.2XP_016880898.1  nuclear receptor corepressor 1 isoform X5

    Conserved Domains (3) summary
    cd00167
    Location:627670
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:683857
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  16. XM_006721602.4XP_006721665.1  nuclear receptor corepressor 1 isoform X2

    See identical proteins and their annotated locations for XP_006721665.1

    Conserved Domains (3) summary
    cd00167
    Location:636679
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:692866
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  17. XM_017025403.2XP_016880892.1  nuclear receptor corepressor 1 isoform X4

    Conserved Domains (3) summary
    cd00167
    Location:628671
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:684858
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  18. XM_006721604.4XP_006721667.1  nuclear receptor corepressor 1 isoform X10

    Conserved Domains (4) summary
    smart00717
    Location:627672
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:627670
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam05285
    Location:678760
    SDA1; SDA1
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  19. XM_005256872.5XP_005256929.1  nuclear receptor corepressor 1 isoform X5

    Conserved Domains (3) summary
    cd00167
    Location:627670
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:683857
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  20. XM_005256871.5XP_005256928.1  nuclear receptor corepressor 1 isoform X4

    Conserved Domains (3) summary
    cd00167
    Location:628671
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:684858
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  21. XM_005256866.5XP_005256923.1  nuclear receptor corepressor 1 isoform X1

    See identical proteins and their annotated locations for XP_005256923.1

    Conserved Domains (4) summary
    smart00717
    Location:637682
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:637680
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam05285
    Location:688770
    SDA1; SDA1
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  22. XM_005256868.5XP_005256925.1  nuclear receptor corepressor 1 isoform X2

    See identical proteins and their annotated locations for XP_005256925.1

    Conserved Domains (3) summary
    cd00167
    Location:636679
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:692866
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  23. XM_017025420.2XP_016880909.1  nuclear receptor corepressor 1 isoform X17

  24. XM_017025417.2XP_016880906.1  nuclear receptor corepressor 1 isoform X11

  25. XM_005256873.5XP_005256930.1  nuclear receptor corepressor 1 isoform X7

    Conserved Domains (3) summary
    smart00717
    Location:637682
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:637680
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  26. XM_017025419.2XP_016880908.1  nuclear receptor corepressor 1 isoform X15

  27. XM_005256874.5XP_005256931.1  nuclear receptor corepressor 1 isoform X8

    Conserved Domains (4) summary
    smart00717
    Location:637682
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:637680
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam05285
    Location:688770
    SDA1; SDA1
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  28. XM_005256875.4XP_005256932.1  nuclear receptor corepressor 1 isoform X12

    Conserved Domains (4) summary
    smart00717
    Location:637682
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:637680
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam05285
    Location:688770
    SDA1; SDA1
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  29. XM_011524085.3XP_011522387.1  nuclear receptor corepressor 1 isoform X13

    Conserved Domains (4) summary
    smart00717
    Location:637682
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:637680
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam05285
    Location:688770
    SDA1; SDA1
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  30. XM_017025410.2XP_016880899.1  nuclear receptor corepressor 1 isoform X5

    Conserved Domains (3) summary
    cd00167
    Location:627670
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:683857
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  31. XM_017025404.2XP_016880893.1  nuclear receptor corepressor 1 isoform X4

    Conserved Domains (3) summary
    cd00167
    Location:628671
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:684858
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  32. XM_024451041.1XP_024306809.1  nuclear receptor corepressor 1 isoform X2

    Conserved Domains (3) summary
    cd00167
    Location:636679
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:692866
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  33. XM_017025398.2XP_016880887.1  nuclear receptor corepressor 1 isoform X1

    Conserved Domains (4) summary
    smart00717
    Location:637682
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:637680
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam05285
    Location:688770
    SDA1; SDA1
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  34. XM_024451043.1XP_024306811.1  nuclear receptor corepressor 1 isoform X5

    Conserved Domains (3) summary
    cd00167
    Location:627670
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:683857
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  35. XM_017025407.2XP_016880896.1  nuclear receptor corepressor 1 isoform X4

    Conserved Domains (3) summary
    cd00167
    Location:628671
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:684858
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  36. XM_017025414.2XP_016880903.1  nuclear receptor corepressor 1 isoform X5

    Conserved Domains (3) summary
    cd00167
    Location:627670
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:683857
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  37. XM_017025412.2XP_016880901.1  nuclear receptor corepressor 1 isoform X5

    Conserved Domains (3) summary
    cd00167
    Location:627670
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:683857
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  38. XM_017025405.2XP_016880894.1  nuclear receptor corepressor 1 isoform X4

    Conserved Domains (3) summary
    cd00167
    Location:628671
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:684858
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  39. XM_017025399.2XP_016880888.1  nuclear receptor corepressor 1 isoform X1

    Conserved Domains (4) summary
    smart00717
    Location:637682
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd00167
    Location:637680
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam05285
    Location:688770
    SDA1; SDA1
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
  40. XM_017025408.2XP_016880897.1  nuclear receptor corepressor 1 isoform X4

    Conserved Domains (3) summary
    cd00167
    Location:628671
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:684858
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  41. XM_017025413.2XP_016880902.1  nuclear receptor corepressor 1 isoform X5

    Conserved Domains (3) summary
    cd00167
    Location:627670
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:683857
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  42. XM_024451042.1XP_024306810.1  nuclear receptor corepressor 1 isoform X4

    Conserved Domains (3) summary
    cd00167
    Location:628671
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:684858
    DNA_pol3_delta2; DNA polymerase III, delta subunit
  43. XM_017025402.2XP_016880891.1  nuclear receptor corepressor 1 isoform X2

    Conserved Domains (3) summary
    cd00167
    Location:636679
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    pfam15784
    Location:150237
    GPS2_interact; G-protein pathway suppressor 2-interacting domain
    cl26247
    Location:692866
    DNA_pol3_delta2; DNA polymerase III, delta subunit
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