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    Rab3d RAB3D, member RAS oncogene family [ Mus musculus (house mouse) ]

    Gene ID: 19340, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rab3dprovided by MGI
    Official Full Name
    RAB3D, member RAS oncogene familyprovided by MGI
    Primary source
    MGI:MGI:97844
    See related
    Ensembl:ENSMUSG00000019066
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C130057E11Rik
    Expression
    Broad expression in colon adult (RPKM 51.1), stomach adult (RPKM 49.7) and 23 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rab3d in Genome Data Viewer
    Location:
    9; 9 A3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (21818787..21829623, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (21907491..21918199, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (21711954..21722565, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene dedicator of cytokinesis 6 Neighboring gene microRNA 7083 Neighboring gene angiopoietin-like 8 Neighboring gene transmembrane protein 205 Neighboring gene coiled-coil domain containing 159 Neighboring gene phospholipid phosphatase related 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTP-dependent protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables myosin V binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in bone resorption ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within exocytosis IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within peptidyl-cysteine methylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of regulated secretory pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization to plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein secretion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within regulation of exocytosis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in vesicle docking involved in exocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasmic microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrion HDA PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in secretory vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synaptic vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in transport vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in zymogen granule IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    ras-related protein Rab-3D
    NP_001311460.1
    NP_114080.2
    XP_011240724.1
    XP_011240725.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001324531.1NP_001311460.1  ras-related protein Rab-3D

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice acceptor site in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK048395, AK169369, BQ033745
      Consensus CDS
      CCDS22912.1
      UniProtKB/Swiss-Prot
      P35276
      UniProtKB/TrEMBL
      Q543Q4
      Related
      ENSMUSP00000111008.4, ENSMUST00000115351.10
      Conserved Domains (1) summary
      cd01865
      Location:22186
      Rab3; Rab GTPase family 3 contains Rab3A, Rab3B, Rab3C and Rab3D
    2. NM_031874.5NP_114080.2  ras-related protein Rab-3D

      See identical proteins and their annotated locations for NP_114080.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK048395, AK169369, BQ033745, CN696618
      Consensus CDS
      CCDS22912.1
      UniProtKB/Swiss-Prot
      P35276
      UniProtKB/TrEMBL
      Q543Q4
      Related
      ENSMUSP00000113322.2, ENSMUST00000122211.8
      Conserved Domains (1) summary
      cd01865
      Location:22186
      Rab3; Rab GTPase family 3 contains Rab3A, Rab3B, Rab3C and Rab3D

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      21818787..21829623 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011242423.4XP_011240725.1  ras-related protein Rab-3D isoform X1

      See identical proteins and their annotated locations for XP_011240725.1

      UniProtKB/Swiss-Prot
      P35276
      UniProtKB/TrEMBL
      Q543Q4
      Conserved Domains (1) summary
      cd01865
      Location:22186
      Rab3; Rab GTPase family 3 contains Rab3A, Rab3B, Rab3C and Rab3D
    2. XM_011242422.4XP_011240724.1  ras-related protein Rab-3D isoform X1

      See identical proteins and their annotated locations for XP_011240724.1

      UniProtKB/Swiss-Prot
      P35276
      UniProtKB/TrEMBL
      Q543Q4
      Conserved Domains (1) summary
      cd01865
      Location:22186
      Rab3; Rab GTPase family 3 contains Rab3A, Rab3B, Rab3C and Rab3D
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