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    Lyar Ly1 antibody reactive clone [ Mus musculus (house mouse) ]

    Gene ID: 17089, updated on 23-Jun-2021

    Summary

    Official Symbol
    Lyarprovided by MGI
    Official Full Name
    Ly1 antibody reactive cloneprovided by MGI
    Primary source
    MGI:MGI:107470
    See related
    Ensembl:ENSMUSG00000067367
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MLZ-264
    Expression
    Biased expression in testis adult (RPKM 89.4), liver E14 (RPKM 24.9) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Lyar in Genome Data Viewer
    Location:
    5 B3; 5 20.29 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (38377815..38391650)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (38220471..38234306)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (38611721..38625545)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene syntaxin 18 Neighboring gene neuron specific gene family member 1 Neighboring gene zinc finger and BTB domain containing 49 Neighboring gene transmembrane protein 128 Neighboring gene otopetrin 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA-binding transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables transcription regulator inhibitor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in photoreceptor outer segment IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    cell growth-regulating nucleolar protein
    Names
    ly1 antibody-reactive protein
    protein expressed in male leptotene and zygotene spermatocytes 264

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025281.3NP_079557.2  cell growth-regulating nucleolar protein

      See identical proteins and their annotated locations for NP_079557.2

      Status: VALIDATED

      Source sequence(s)
      BC116923, BY099797, CD776101
      Consensus CDS
      CCDS19253.1
      UniProtKB/Swiss-Prot
      Q08288
      Related
      ENSMUSP00000084791.3, ENSMUST00000087514.9
      Conserved Domains (3) summary
      pfam08790
      Location:3158
      zf-LYAR; LYAR-type C2HC zinc finger
      pfam17848
      Location:328
      zf-ACC; Acetyl-coA carboxylase zinc finger domain
      cl30717
      Location:122300
      InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      38377815..38391650
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006503766.2XP_006503829.1  cell growth-regulating nucleolar protein isoform X2

      See identical proteins and their annotated locations for XP_006503829.1

      Conserved Domains (1) summary
      cl30717
      Location:48227
      InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    2. XM_030254181.1XP_030110041.1  cell growth-regulating nucleolar protein isoform X2

      Conserved Domains (1) summary
      cl30717
      Location:48227
      InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    3. XM_030254182.1XP_030110042.1  cell growth-regulating nucleolar protein isoform X2

      Conserved Domains (1) summary
      cl30717
      Location:48227
      InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    4. XM_006503765.2XP_006503828.1  cell growth-regulating nucleolar protein isoform X2

      See identical proteins and their annotated locations for XP_006503828.1

      Conserved Domains (1) summary
      cl30717
      Location:48227
      InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    5. XM_006503764.3XP_006503827.1  cell growth-regulating nucleolar protein isoform X1

      See identical proteins and their annotated locations for XP_006503827.1

      UniProtKB/Swiss-Prot
      Q08288
      Related
      ENSMUSP00000109741.2, ENSMUST00000114106.8
      Conserved Domains (3) summary
      pfam08790
      Location:3158
      zf-LYAR; LYAR-type C2HC zinc finger
      pfam17848
      Location:328
      zf-ACC; Acetyl-coA carboxylase zinc finger domain
      cl30717
      Location:122300
      InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    6. XM_006503759.3XP_006503822.1  cell growth-regulating nucleolar protein isoform X1

      See identical proteins and their annotated locations for XP_006503822.1

      UniProtKB/Swiss-Prot
      Q08288
      Conserved Domains (3) summary
      pfam08790
      Location:3158
      zf-LYAR; LYAR-type C2HC zinc finger
      pfam17848
      Location:328
      zf-ACC; Acetyl-coA carboxylase zinc finger domain
      cl30717
      Location:122300
      InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    7. XM_006503761.3XP_006503824.1  cell growth-regulating nucleolar protein isoform X1

      See identical proteins and their annotated locations for XP_006503824.1

      UniProtKB/Swiss-Prot
      Q08288
      Conserved Domains (3) summary
      pfam08790
      Location:3158
      zf-LYAR; LYAR-type C2HC zinc finger
      pfam17848
      Location:328
      zf-ACC; Acetyl-coA carboxylase zinc finger domain
      cl30717
      Location:122300
      InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    8. XM_006503760.3XP_006503823.1  cell growth-regulating nucleolar protein isoform X1

      See identical proteins and their annotated locations for XP_006503823.1

      UniProtKB/Swiss-Prot
      Q08288
      Conserved Domains (3) summary
      pfam08790
      Location:3158
      zf-LYAR; LYAR-type C2HC zinc finger
      pfam17848
      Location:328
      zf-ACC; Acetyl-coA carboxylase zinc finger domain
      cl30717
      Location:122300
      InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
    9. XM_006503762.3XP_006503825.1  cell growth-regulating nucleolar protein isoform X1

      See identical proteins and their annotated locations for XP_006503825.1

      UniProtKB/Swiss-Prot
      Q08288
      Conserved Domains (3) summary
      pfam08790
      Location:3158
      zf-LYAR; LYAR-type C2HC zinc finger
      pfam17848
      Location:328
      zf-ACC; Acetyl-coA carboxylase zinc finger domain
      cl30717
      Location:122300
      InfB; Translation initiation factor IF-2, a GTPase [Translation, ribosomal structure and biogenesis]
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