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    Cetn3 centrin 3 [ Mus musculus (house mouse) ]

    Gene ID: 12626, updated on 9-Sep-2018

    Summary

    Official Symbol
    Cetn3provided by MGI
    Official Full Name
    centrin 3provided by MGI
    Primary source
    MGI:MGI:1097706
    See related
    Ensembl:ENSMUSG00000021537
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MmCEN3
    Expression
    Biased expression in CNS E18 (RPKM 18.1), CNS E11.5 (RPKM 17.0) and 14 other tissues See more
    Orthologs

    Genomic context

    See Cetn3 in Genome Data Viewer
    Location:
    13; 13 C3
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (81783249..81797157)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (81922291..81936156)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene polymerase (RNA) III (DNA directed) polypeptide G Neighboring gene metallo-beta-lactamase domain containing 2 Neighboring gene predicted gene, 32836 Neighboring gene predicted gene, 41008

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    G-protein beta/gamma-subunit complex binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    calcium ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    microtubule binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    calcium-mediated signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule nucleation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitotic spindle pole body duplication IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    spindle pole body duplication IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    centriole IDA
    Inferred from Direct Assay
    more info
    PubMed 
    centriole ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    centrosome ISO
    Inferred from Sequence Orthology
    more info
     
    ciliary basal body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ciliary transition zone IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    half bridge of spindle pole body IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    colocalizes_with nucleotide-excision repair factor 2 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    photoreceptor connecting cilium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription export complex 2 IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007684.4NP_031710.1  centrin-3

      See identical proteins and their annotated locations for NP_031710.1

      Status: VALIDATED

      Source sequence(s)
      AI851499, AK006891, BY103593
      Consensus CDS
      CCDS26663.1
      UniProtKB/Swiss-Prot
      O35648
      UniProtKB/TrEMBL
      Q545L8
      Related
      ENSMUSP00000022009.8, ENSMUST00000022009.9
      Conserved Domains (1) summary
      cl25352
      Location:15166
      EFh_PEF; The penta-EF hand (PEF) family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      81783249..81797157
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006517074.3XP_006517137.1  centrin-3 isoform X1

      Conserved Domains (2) summary
      cd00051
      Location:102157
      EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
      pfam13499
      Location:3090
      EF-hand_7; EF-hand domain pair
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