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    Atp6v0e ATPase, H+ transporting, lysosomal V0 subunit E [ Mus musculus (house mouse) ]

    Gene ID: 11974, updated on 26-Sep-2022

    Summary

    Official Symbol
    Atp6v0eprovided by MGI
    Official Full Name
    ATPase, H+ transporting, lysosomal V0 subunit Eprovided by MGI
    Primary source
    MGI:MGI:1328318
    See related
    Ensembl:ENSMUSG00000015575 AllianceGenome:MGI:1328318
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    M9.2; Atp6k; Atp6v0e1
    Summary
    Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to be involved in proton transmembrane transport. Predicted to act upstream of or within ion transport. Predicted to be located in membrane. Predicted to be part of proton-transporting V-type ATPase, V0 domain. Is expressed in several structures, including alimentary system; cranium; heart; nervous system; and sensory organ. Orthologous to human ATP6V0E1 (ATPase H+ transporting V0 subunit e1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in genital fat pad adult (RPKM 163.1), kidney adult (RPKM 139.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Atp6v0e in Genome Data Viewer
    Location:
    17; 17 A3.3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (26895370..26918621)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (26676396..26699647)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700049J03 gene Neighboring gene ribosomal protein S2 pseudogene Neighboring gene endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 Neighboring gene predicted gene, 41553 Neighboring gene CREB3 regulatory factor Neighboring gene BCL2/adenovirus E1B interacting protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables proton-transporting ATPase activity, rotational mechanism ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within proton transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    involved_in proton transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of ATPase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    part_of proton-transporting V-type ATPase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of proton-transporting V-type ATPase, V0 domain ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    part_of transmembrane transporter complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    V-type proton ATPase subunit e 1
    Names
    ATPase, H+ transporting lysosomal (vacuolar proton pump), 9.2 kDa
    ATPase, H+ transporting, V0 subunit e
    ATPase, H+ transporting, lysosomal 9kD V0 subunit E
    V-ATPase subunit e 1
    lysosomal 9kDa
    vacuolar proton pump subunit e 1
    NP_079548.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025272.2NP_079548.1  V-type proton ATPase subunit e 1

      See identical proteins and their annotated locations for NP_079548.1

      Status: VALIDATED

      Source sequence(s)
      AK017760, BY707658
      Consensus CDS
      CCDS28554.1
      UniProtKB/Swiss-Prot
      Q9CQD8
      UniProtKB/TrEMBL
      A0A6P5NYR8, A0A8C6I368
      Related
      ENSMUSP00000015719.9, ENSMUST00000015719.16
      Conserved Domains (1) summary
      pfam05493
      Location:967
      ATP_synt_H; ATP synthase subunit H

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      26895370..26918621
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)