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    Atp5f1 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1 [ Mus musculus (house mouse) ]

    Gene ID: 11950, updated on 31-Jan-2019

    Summary

    Official Symbol
    Atp5f1provided by MGI
    Official Full Name
    ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1provided by MGI
    Primary source
    MGI:MGI:1100495
    See related
    Ensembl:ENSMUSG00000000563
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Atp5pb; C76477
    Expression
    Ubiquitous expression in duodenum adult (RPKM 196.9), heart adult (RPKM 162.8) and 28 other tissues See more
    Orthologs

    Genomic context

    See Atp5f1 in Genome Data Viewer
    Location:
    3 F2.2; 3 46.46 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (105942678..105960248, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (105745781..105763166, complement)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene transmembrane and immunoglobulin domain containing 3 Neighboring gene adenosine A3 receptor Neighboring gene RIKEN cDNA I830077J02 gene Neighboring gene WD repeat domain 77 Neighboring gene oviductal glycoprotein 1 Neighboring gene primary cilia formation

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    contributes_to ATPase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    proton transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to proton-transporting ATP synthase activity, rotational mechanism IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    ATP synthesis coupled proton transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ion transport IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ATP synthase F(0) complex subunit B1, mitochondrial
    Names
    ATP synthase peripheral stalk-membrane subunit b
    ATP synthase subunit b, mitochondrial
    ATPase subunit b

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001304719.1NP_001291648.1  ATP synthase F(0) complex subunit B1, mitochondrial isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate exon in the 5' region and uses an alternate start codon compared to variant 1. It encodes isoform 2 which has a shorter and distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AK150730, BC087882, BY602471
      UniProtKB/TrEMBL
      Q5I0W0
      Conserved Domains (1) summary
      pfam05405
      Location:58219
      Mt_ATP-synt_B; Mitochondrial ATP synthase B chain precursor (ATP-synt_B)
    2. NM_009725.4NP_033855.2  ATP synthase F(0) complex subunit B1, mitochondrial isoform 1

      See identical proteins and their annotated locations for NP_033855.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AK019459, BC087882, BY602471
      Consensus CDS
      CCDS17714.1
      UniProtKB/Swiss-Prot
      Q9CQQ7
      UniProtKB/TrEMBL
      Q5I0W0
      Related
      ENSMUSP00000113022.1, ENSMUST00000118209.7
      Conserved Domains (1) summary
      pfam05405
      Location:83244
      Mt_ATP-synt_B; Mitochondrial ATP synthase B chain precursor (ATP-synt_B)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      105942678..105960248 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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