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    pan2 poly(A) specific ribonuclease subunit PAN2 [ Cynoglossus semilaevis (tongue sole) ]

    Gene ID: 103385565, updated on 11-Mar-2024

    Summary

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    Gene symbol
    pan2
    Gene description
    poly(A) specific ribonuclease subunit PAN2
    See related
    Ensembl:ENSCSEG00000021529
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Cynoglossus semilaevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae; Cynoglossinae; Cynoglossus
    Orthologs
    human zebrafish all
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    Genomic context

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    Location:
    chromosome: 10
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    102 current Cse_v1.0 (GCF_000523025.1) 10 NC_024316.1 (20653375..20664921)

    Chromosome 10 - NC_024316.1Genomic Context describing neighboring genes Neighboring gene nuclear envelope integral membrane protein 1 Neighboring gene uncharacterized LOC112487636 Neighboring gene ORMDL sphingolipid biosynthesis regulator 2 Neighboring gene PYM homolog 1, exon junction complex associated factor Neighboring gene uncharacterized LOC103385563

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_024316.1 Chromosome 10 Reference Cse_v1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables poly(A)-specific ribonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in nuclear-transcribed mRNA poly(A) tail shortening IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in P-body IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    part_of PAN complex IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    PAN2-PAN3 deadenylation complex catalytic subunit PAN2
    Names
    PAN2 poly(A) specific ribonuclease subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Cynoglossus semilaevis Annotation Release 102 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Cse_v1.0 Primary Assembly

    Genomic

    1. NC_024316.1 Reference Cse_v1.0 Primary Assembly

      Range
      20653375..20664921
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_008319495.2 → XP_008317717.1  PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1

      See identical proteins and their annotated locations for XP_008317717.1

      UniProtKB/TrEMBL
      A0A3P8X5V3
      Conserved Domains (4) summary
      cd06143
      Location:981 → 1143
      PAN2_exo; DEDDh 3'-5' exonuclease domain of the eukaryotic exoribonuclease PAN2
      cd02672
      Location:506 → 928
      Peptidase_C19P; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
      pfam13423
      Location:521 → 904
      UCH_1; Ubiquitin carboxyl-terminal hydrolase
      cl02567
      Location:206 → 361
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    2. XM_025059543.1 → XP_024915311.1  PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X3

      UniProtKB/TrEMBL
      A0A3P8X5V3
      Conserved Domains (2) summary
      cd06143
      Location:981 → 1143
      PAN2_exo; DEDDh 3'-5' exonuclease domain of the eukaryotic exoribonuclease PAN2
      pfam13423
      Location:521 → 904
      UCH_1; Ubiquitin carboxyl-terminal hydrolase

    3. XM_025059542.1 → XP_024915310.1  PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X2

      UniProtKB/TrEMBL
      A0A3P8X3T6, A0A3P8X5V3
      Related
      ENSCSEP00000033542.1, ENSCSET00000033976.1
      Conserved Domains (2) summary
      cd06143
      Location:981 → 1143
      PAN2_exo; DEDDh 3'-5' exonuclease domain of the eukaryotic exoribonuclease PAN2
      pfam13423
      Location:521 → 904
      UCH_1; Ubiquitin carboxyl-terminal hydrolase
    Nucleotide Protein
    Heading Accession and Version

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