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    Clk3 CDC-like kinase 3 [ Mus musculus (house mouse) ]

    Gene ID: 102414, updated on 23-Jun-2021

    Summary

    Official Symbol
    Clk3provided by MGI
    Official Full Name
    CDC-like kinase 3provided by MGI
    Primary source
    MGI:MGI:1098670
    See related
    Ensembl:ENSMUSG00000032316
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI256811
    Expression
    Ubiquitous expression in thymus adult (RPKM 73.1), liver E14.5 (RPKM 33.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Clk3 in Genome Data Viewer
    Location:
    9; 9 B
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (57657904..57673518, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (57750621..57766235, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (57598518..57613667, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene Cyp1a2 5' enhancer Neighboring gene Cyp1a1 5' regulatory region Neighboring gene cytochrome P450, family 1, subfamily a, polypeptide 1 Neighboring gene enhancer of mRNA decapping 3 Neighboring gene predicted gene, 32510 Neighboring gene AT rich interactive domain 3B (BRIGHT-like) Neighboring gene predicted gene 7547

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC36552, MGC103028

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein serine/threonine/tyrosine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein tyrosine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intermediate filament cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    dual specificity protein kinase CLK3
    Names
    cdc2/CDC28-like protein kinase 3
    NP_031739.4
    XP_006510802.1
    XP_017168549.1
    XP_017168550.1
    XP_030099791.1
    XP_030099792.1
    XP_036010394.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007713.5NP_031739.4  dual specificity protein kinase CLK3

      Status: VALIDATED

      Source sequence(s)
      AC122515
      Consensus CDS
      CCDS23232.1
      Related
      ENSMUSP00000150048.2, ENSMUST00000215233.2
      Conserved Domains (1) summary
      cd14214
      Location:142472
      PKc_CLK3; Catalytic domain of the Dual-specificity protein kinase, CDC-like kinase 3

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      57657904..57673518 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017313061.2XP_017168550.1  dual specificity protein kinase CLK3 isoform X3

      Conserved Domains (1) summary
      cl21453
      Location:1251
      PKc_like; Protein Kinases, catalytic domain
    2. XM_006510739.5XP_006510802.1  dual specificity protein kinase CLK3 isoform X2

      See identical proteins and their annotated locations for XP_006510802.1

      UniProtKB/Swiss-Prot
      O35492
      Conserved Domains (1) summary
      cd14214
      Location:142472
      PKc_CLK3; Catalytic domain of the Dual-specificity protein kinase, CDC-like kinase 3
    3. XM_030243932.1XP_030099792.1  dual specificity protein kinase CLK3 isoform X3

      Conserved Domains (1) summary
      cl21453
      Location:1251
      PKc_like; Protein Kinases, catalytic domain
    4. XM_030243931.2XP_030099791.1  dual specificity protein kinase CLK3 isoform X2

      Conserved Domains (1) summary
      cd14214
      Location:142472
      PKc_CLK3; Catalytic domain of the Dual-specificity protein kinase, CDC-like kinase 3
    5. XM_017313060.2XP_017168549.1  dual specificity protein kinase CLK3 isoform X2

      UniProtKB/Swiss-Prot
      O35492
      Conserved Domains (1) summary
      cd14214
      Location:142472
      PKc_CLK3; Catalytic domain of the Dual-specificity protein kinase, CDC-like kinase 3
    6. XM_036154501.1XP_036010394.1  dual specificity protein kinase CLK3 isoform X1

      Conserved Domains (1) summary
      cd14214
      Location:159489
      PKc_CLK3; Catalytic domain of the Dual-specificity protein kinase, CDC-like kinase 3
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