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DOP1B DOP1 leucine zipper like protein B [ Homo sapiens (human) ]

Gene ID: 9980, updated on 4-Oct-2020

Summary

Official Symbol
DOP1Bprovided by HGNC
Official Full Name
DOP1 leucine zipper like protein Bprovided by HGNC
Primary source
HGNC:HGNC:1291
See related
Ensembl:ENSG00000142197 MIM:604803
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
21orf5; DOPEY2; C21orf5
Expression
Ubiquitous expression in colon (RPKM 9.1), bone marrow (RPKM 8.2) and 25 other tissues See more
Orthologs

Genomic context

See DOP1B in Genome Data Viewer
Location:
21q22.12
Exon count:
39
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 21 NC_000021.9 (36156781..36294274)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (37529080..37666572)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene CBR3 antisense RNA 1 Neighboring gene ribosomal protein S9 pseudogene 1 Neighboring gene carbonyl reductase 3 Neighboring gene ribosomal protein L3 pseudogene 1 Neighboring gene serine and arginine rich splicing factor 9 pseudogene 1 Neighboring gene ribosomal protein S26 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
Golgi to endosome transport ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
cognition IMP
Inferred from Mutant Phenotype
more info
PubMed 
endoplasmic reticulum organization ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
multicellular organism development NAS
Non-traceable Author Statement
more info
PubMed 
protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
cytosol IEA
Inferred from Electronic Annotation
more info
 
endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular exosome HDA PubMed 
trans-Golgi network IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
protein dopey-2
Names
dopey family member 2
homolog of yeast DOP1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001320714.2NP_001307643.1  protein dopey-2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AB023150, AP000689, AP000690, AP000691, AP000692, BP364624, BP365117, W15495
    Consensus CDS
    CCDS13643.1
    UniProtKB/Swiss-Prot
    Q9Y3R5
    Conserved Domains (2) summary
    pfam04118
    Location:13308
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:19512107
    Dopey_N; Dopey, N-terminal
  2. NM_005128.4NP_005119.2  protein dopey-2

    See identical proteins and their annotated locations for NP_005119.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AJ237839, AP000689, AP000690, AP000691, BC012791, W15495
    Consensus CDS
    CCDS13643.1
    UniProtKB/Swiss-Prot
    Q9Y3R5
    Related
    ENSP00000382104.3, ENST00000399151.3
    Conserved Domains (2) summary
    pfam04118
    Location:13308
    Dopey_N; Dopey, N-terminal
    cl04407
    Location:19512107
    Dopey_N; Dopey, N-terminal

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p13 Primary Assembly

    Range
    36156781..36294274
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017028509.1XP_016883998.1  protein dopey-2 isoform X1

RNA

  1. XR_001754923.2 RNA Sequence

  2. XR_937581.3 RNA Sequence

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