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SNAP91 synaptosome associated protein 91 [ Homo sapiens (human) ]

Gene ID: 9892, updated on 10-Oct-2020

Summary

Official Symbol
SNAP91provided by HGNC
Official Full Name
synaptosome associated protein 91provided by HGNC
Primary source
HGNC:HGNC:14986
See related
Ensembl:ENSG00000065609 MIM:607923
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CALM; AP180
Expression
Biased expression in brain (RPKM 42.7), testis (RPKM 6.2) and 1 other tissue See more
Orthologs

Genomic context

See SNAP91 in Genome Data Viewer
Location:
6q14.2
Exon count:
44
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (83552885..83709408, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (84262604..84419127, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene malic enzyme 1 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene serine protease 35 Neighboring gene uncharacterized LOC105377879 Neighboring gene ripply transcriptional repressor 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Phenotypes

Associated conditions

Description Tests
Genome-wide association of mood-incongruent psychotic bipolar disorder.
GeneReviews: Not available

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Vpu vpu The C-terminal fragment of the clathrin assembly protein AP180 inhibits the downregulation of BST-2 from the cell surface by HIV-1 Vpu and HIV-2 Env PubMed
capsid gag AP180 depletion by shRNA results in inhibition of the HIV-1 CA uptake by target cells PubMed

Go to the HIV-1, Human Interaction Database

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0656, DKFZp781O0519

Gene Ontology Provided by GOA

Function Evidence Code Pubs
1-phosphatidylinositol binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
clathrin heavy chain binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatidylinositol-4,5-bisphosphate binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase binding ISS
Inferred from Sequence or Structural Similarity
more info
 
Process Evidence Code Pubs
clathrin coat assembly IEA
Inferred from Electronic Annotation
more info
 
clathrin-dependent endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein transport IEA
Inferred from Electronic Annotation
more info
 
regulation of clathrin-dependent endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
synaptic vesicle budding from presynaptic endocytic zone membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synaptic vesicle endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
vesicle budding from membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
clathrin-coated pit IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
clathrin-coated vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extrinsic component of presynaptic endocytic zone membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
presynaptic membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
synaptic vesicle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
clathrin coat assembly protein AP180
Names
91 kDa synaptosomal-associated protein
assembly protein, 180kDa
clathrin coat-associated protein AP180
phosphoprotein F1-20
synaptosomal-associated protein, 91kDa homolog
synaptosome associated protein 91kDa

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001242792.2NP_001229721.1  clathrin coat assembly protein AP180 isoform a

    See identical proteins and their annotated locations for NP_001229721.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1 and 3 both encode the same isoform (a).
    Source sequence(s)
    AB014556, AK289582, AL109915, BC044579
    Consensus CDS
    CCDS47455.1
    UniProtKB/Swiss-Prot
    O60641
    Related
    ENSP00000358708.2, ENST00000369694.6
    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:595897
    Atrophin-1; Atrophin-1 family
  2. NM_001242793.1NP_001229722.1  clathrin coat assembly protein AP180 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an internal segment in the 5' UTR and two in-frame exons in the CDS, compared to variant 1. The resulting isoform (b) lacks two internal segments, compared to isoform a. Variants 4 and 42-45 all encode the same isoform (b).
    Source sequence(s)
    AK289582, BC036650, BC044579, DB480068
    Consensus CDS
    CCDS56438.1
    UniProtKB/Swiss-Prot
    O60641
    Related
    ENSP00000428511.1, ENST00000520302.5
    Conserved Domains (2) summary
    PHA03247
    Location:697867
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  3. NM_001242794.1NP_001229723.1  clathrin coat assembly protein AP180 isoform c

    See identical proteins and their annotated locations for NP_001229723.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks an internal segment in the 5' UTR and multiple exons in the CDS, compared to variant 1. The resulting isoform (c) lacks three internal segments, compared to isoform a.
    Source sequence(s)
    BC044579, BC060818, DA316497, DB480068
    Consensus CDS
    CCDS56437.1
    UniProtKB/Swiss-Prot
    O60641
    Related
    ENSP00000428026.1, ENST00000520213.5
    Conserved Domains (2) summary
    pfam07651
    Location:21270
    ANTH; ANTH domain
    cl26464
    Location:282590
    Atrophin-1; Atrophin-1 family
  4. NM_001256717.1NP_001243646.1  clathrin coat assembly protein AP180 isoform d

    See identical proteins and their annotated locations for NP_001243646.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (d) has a distinct N-terminus and is shorter than isoform a.
    Source sequence(s)
    BC036650, BC044579, CR749348, DA110036
    UniProtKB/Swiss-Prot
    O60641
    Conserved Domains (1) summary
    pfam07651
    Location:10249
    ANTH; ANTH domain
  5. NM_001256718.2NP_001243647.1  clathrin coat assembly protein AP180 isoform e

    See identical proteins and their annotated locations for NP_001243647.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (7) differs in the 5' UTR, contains multiple differences in the coding region, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (e) is shorter than isoform a.
    Source sequence(s)
    AK294898, AL109915, BC036650, BC044579, CR749348, DA307867
    UniProtKB/Swiss-Prot
    O60641
    UniProtKB/TrEMBL
    B7Z2N2
    Conserved Domains (1) summary
    cl02544
    Location:1165
    VHS_ENTH_ANTH; VHS, ENTH and ANTH domain superfamily; composed of proteins containing a VHS, ENTH or ANTH domain. The VHS domain is present in Vps27 (Vacuolar Protein Sorting), Hrs (Hepatocyte growth factor-regulated tyrosine kinase substrate) and STAM (Signal ...
  6. NM_001363677.1NP_001350606.1  clathrin coat assembly protein AP180 isoform f

    Status: VALIDATED

    Description
    Transcript Variant: This variant (8) differs in the 5' UTR and uses an alternate in-frame splice junction compared to variant 1. The resulting isoform (f) has the same N- and C-termini but is shorter compared to isoform a.
    Source sequence(s)
    AL109915
    Consensus CDS
    CCDS87418.1
    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:671892
    Atrophin-1; Atrophin-1 family
  7. NM_001376675.1NP_001363604.1  clathrin coat assembly protein AP180 isoform g

    Status: VALIDATED

    Description
    Transcript Variant: This variant (9), as well as variants 10-16, encodes isoform g.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:593895
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  8. NM_001376676.1NP_001363605.1  clathrin coat assembly protein AP180 isoform g

    Status: VALIDATED

    Description
    Transcript Variant: This variant (10), as well as variants 9 and 11-16, encodes isoform g.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:593895
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  9. NM_001376677.1NP_001363606.1  clathrin coat assembly protein AP180 isoform g

    Status: VALIDATED

    Description
    Transcript Variant: This variant (11), as well as variants 9, 10, and 12-16, encodes isoform g.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:593895
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  10. NM_001376678.1NP_001363607.1  clathrin coat assembly protein AP180 isoform g

    Status: VALIDATED

    Description
    Transcript Variant: This variant (12), as well as variants 9-11 and 13-16, encodes isoform g.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:593895
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  11. NM_001376679.1NP_001363608.1  clathrin coat assembly protein AP180 isoform g

    Status: VALIDATED

    Description
    Transcript Variant: This variant (13), as well as variants 9-12 and 14-16, encodes isoform g.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:593895
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  12. NM_001376680.1NP_001363609.1  clathrin coat assembly protein AP180 isoform g

    Status: VALIDATED

    Description
    Transcript Variant: This variant (14), as well as variants 9-13, 15, and 16, encodes isoform g.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:593895
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  13. NM_001376681.1NP_001363610.1  clathrin coat assembly protein AP180 isoform g

    Status: VALIDATED

    Description
    Transcript Variant: This variant (15), as well as variants 9-14 and 16, encodes isoform g.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:593895
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  14. NM_001376682.1NP_001363611.1  clathrin coat assembly protein AP180 isoform g

    Status: VALIDATED

    Description
    Transcript Variant: This variant (16), as well as variants 9-15, encodes isoform g.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:593895
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  15. NM_001376683.1NP_001363612.1  clathrin coat assembly protein AP180 isoform h

    Status: VALIDATED

    Description
    Transcript Variant: This variant (17), as well as variant 18, encodes isoform h.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:592894
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  16. NM_001376684.1NP_001363613.1  clathrin coat assembly protein AP180 isoform h

    Status: VALIDATED

    Description
    Transcript Variant: This variant (18), as well as variant 17, encodes isoform h.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:592894
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  17. NM_001376685.1NP_001363614.1  clathrin coat assembly protein AP180 isoform i

    Status: VALIDATED

    Description
    Transcript Variant: This variant (20), as well as variants 21-26, encodes isoform i.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:669890
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  18. NM_001376686.1NP_001363615.1  clathrin coat assembly protein AP180 isoform i

    Status: VALIDATED

    Description
    Transcript Variant: This variant (21), as well as variants 20 and 22-26, encodes isoform i.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:669890
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  19. NM_001376687.1NP_001363616.1  clathrin coat assembly protein AP180 isoform gg

    Status: VALIDATED

    Source sequence(s)
    AL109915
  20. NM_001376688.1NP_001363617.1  clathrin coat assembly protein AP180 isoform i

    Status: VALIDATED

    Description
    Transcript Variant: This variant (22), as well as variants 20, 21, and 23-26, encodes isoform i.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:669890
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  21. NM_001376689.1NP_001363618.1  clathrin coat assembly protein AP180 isoform i

    Status: VALIDATED

    Description
    Transcript Variant: This variant (23), as well as variants 20-22 and 24-26, encodes isoform i.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:669890
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  22. NM_001376690.1NP_001363619.1  clathrin coat assembly protein AP180 isoform i

    Status: VALIDATED

    Description
    Transcript Variant: This variant (24), as well as variants 20-23, 25, and 26, encodes isoform i.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:669890
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  23. NM_001376691.1NP_001363620.1  clathrin coat assembly protein AP180 isoform i

    Status: VALIDATED

    Description
    Transcript Variant: This variant (25), as well as variants 20-24 and 26, encodes isoform i.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:669890
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  24. NM_001376692.1NP_001363621.1  clathrin coat assembly protein AP180 isoform i

    Status: VALIDATED

    Description
    Transcript Variant: This variant (26), as well as variants 20-25, encodes isoform i.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:669890
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  25. NM_001376693.1NP_001363622.1  clathrin coat assembly protein AP180 isoform j

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:586888
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  26. NM_001376694.1NP_001363623.1  clathrin coat assembly protein AP180 isoform k

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:717887
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  27. NM_001376695.1NP_001363624.1  clathrin coat assembly protein AP180 isoform l

    Status: VALIDATED

    Description
    Transcript Variant: This variant (29), as well as variants 30-32, encodes isoform l.
    Source sequence(s)
    AL109915
  28. NM_001376696.1NP_001363625.1  clathrin coat assembly protein AP180 isoform l

    Status: VALIDATED

    Description
    Transcript Variant: This variant (30), as well as variants 29, 31, and 32, encodes isoform l.
    Source sequence(s)
    AL109915
  29. NM_001376697.1NP_001363626.1  clathrin coat assembly protein AP180 isoform l

    Status: VALIDATED

    Description
    Transcript Variant: This variant (31), as well as variants 29, 30, and 32, encodes isoform l.
    Source sequence(s)
    AL109915
  30. NM_001376698.1NP_001363627.1  clathrin coat assembly protein AP180 isoform l

    Status: VALIDATED

    Description
    Transcript Variant: This variant (32), as well as variants 29-31, encodes isoform l.
    Source sequence(s)
    AL109915
  31. NM_001376699.1NP_001363628.1  clathrin coat assembly protein AP180 isoform m

    Status: VALIDATED

    Description
    Transcript Variant: This variant (33), as well as variant 34, encodes isoform m.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:669880
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  32. NM_001376700.1NP_001363629.1  clathrin coat assembly protein AP180 isoform m

    Status: VALIDATED

    Description
    Transcript Variant: This variant (34), as well as variant 33, encodes isoform m.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:669880
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  33. NM_001376701.1NP_001363630.1  clathrin coat assembly protein AP180 isoform n

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:655876
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24269
    ANTH; ANTH domain
  34. NM_001376702.1NP_001363631.1  clathrin coat assembly protein AP180 isoform o

    Status: VALIDATED

    Description
    Transcript Variant: This variant (36), as well as variants 37-41, encodes isoform o.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:567869
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  35. NM_001376703.1NP_001363632.1  clathrin coat assembly protein AP180 isoform o

    Status: VALIDATED

    Description
    Transcript Variant: This variant (37), as well as variants 36 and 38-41, encodes isoform o.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:567869
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  36. NM_001376704.1NP_001363633.1  clathrin coat assembly protein AP180 isoform o

    Status: VALIDATED

    Description
    Transcript Variant: This variant (38), as well as variants 36, 37, and 39-41, encodes isoform o.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:567869
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  37. NM_001376705.1NP_001363634.1  clathrin coat assembly protein AP180 isoform o

    Status: VALIDATED

    Description
    Transcript Variant: This variant (39), as well as variants 36-38, 40, and 41, encodes isoform o.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:567869
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  38. NM_001376706.1NP_001363635.1  clathrin coat assembly protein AP180 isoform o

    Status: VALIDATED

    Description
    Transcript Variant: This variant (40), as well as variants 36-39 and 41, encodes isoform o.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:567869
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  39. NM_001376707.1NP_001363636.1  clathrin coat assembly protein AP180 isoform o

    Status: VALIDATED

    Description
    Transcript Variant: This variant (41), as well as variants 36-40, encodes isoform o.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:567869
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  40. NM_001376708.1NP_001363637.1  clathrin coat assembly protein AP180 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (42), as well as variants 4 and 43-45, encodes isoform b.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:697867
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  41. NM_001376709.1NP_001363638.1  clathrin coat assembly protein AP180 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (43), as well as variants 4, 42, 44, and 45, encodes isoform b.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:697867
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  42. NM_001376710.1NP_001363639.1  clathrin coat assembly protein AP180 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (44), as well as variants 4, 42, 43, and 45, encodes isoform b.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:697867
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  43. NM_001376711.1NP_001363640.1  clathrin coat assembly protein AP180 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (45), as well as variants 4 and 42-44, encodes isoform b.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:697867
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  44. NM_001376712.1NP_001363641.1  clathrin coat assembly protein AP180 isoform hh

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:588872
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  45. NM_001376713.1NP_001363642.1  clathrin coat assembly protein AP180 isoform p

    Status: VALIDATED

    Description
    Transcript Variant: This variant (47), as well as variant 48, encodes isoform p.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:643864
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  46. NM_001376714.1NP_001363643.1  clathrin coat assembly protein AP180 isoform p

    Status: VALIDATED

    Description
    Transcript Variant: This variant (48), as well as variant 47, encodes isoform p.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:643864
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  47. NM_001376715.1NP_001363644.1  clathrin coat assembly protein AP180 isoform q

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:638859
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:15252
    ANTH; ANTH domain
  48. NM_001376716.1NP_001363645.1  clathrin coat assembly protein AP180 isoform r

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:553855
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24269
    ANTH; ANTH domain
  49. NM_001376717.1NP_001363646.1  clathrin coat assembly protein AP180 isoform s

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:629850
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24269
    ANTH; ANTH domain
  50. NM_001376718.1NP_001363647.1  clathrin coat assembly protein AP180 isoform t

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:675845
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  51. NM_001376719.1NP_001363648.1  clathrin coat assembly protein AP180 isoform u

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:671841
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  52. NM_001376720.1NP_001363649.1  clathrin coat assembly protein AP180 isoform v

    Status: VALIDATED

    Description
    Transcript Variant: This variant (54), as well as variants 55-58, encodes isoform v.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:667837
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:1225
    ANTH; ANTH domain
  53. NM_001376721.1NP_001363650.1  clathrin coat assembly protein AP180 isoform v

    Status: VALIDATED

    Description
    Transcript Variant: This variant (55), as well as variants 54 and 56-58, encodes isoform v.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:667837
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:1225
    ANTH; ANTH domain
  54. NM_001376723.1NP_001363652.1  clathrin coat assembly protein AP180 isoform v

    Status: VALIDATED

    Description
    Transcript Variant: This variant (56), as well as variants 54, 55, 57, and 58, encodes isoform v.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:667837
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:1225
    ANTH; ANTH domain
  55. NM_001376726.1NP_001363655.1  clathrin coat assembly protein AP180 isoform v

    Status: VALIDATED

    Description
    Transcript Variant: This variant (57), as well as variants 54-56 and 58, encodes isoform v.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:667837
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:1225
    ANTH; ANTH domain
  56. NM_001376728.1NP_001363657.1  clathrin coat assembly protein AP180 isoform v

    Status: VALIDATED

    Description
    Transcript Variant: This variant (58), as well as variants 54-57, encodes isoform v.
    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:667837
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:1225
    ANTH; ANTH domain
  57. NM_001376731.1NP_001363660.1  clathrin coat assembly protein AP180 isoform w

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:615836
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  58. NM_001376733.1NP_001363662.1  clathrin coat assembly protein AP180 isoform x

    Status: VALIDATED

    Description
    Transcript Variant: This variant (60), as well as variant 61, encodes isoform x.
    Source sequence(s)
    AL109915
    Conserved Domains (3) summary
    PHA03247
    Location:562830
    PHA03247; large tegument protein UL36; Provisional
    PRK12323
    Location:734836
    PRK12323; DNA polymerase III subunit gamma/tau
    pfam07651
    Location:24283
    ANTH; ANTH domain
  59. NM_001376734.1NP_001363663.1  clathrin coat assembly protein AP180 isoform x

    Status: VALIDATED

    Description
    Transcript Variant: This variant (61), as well as variant 60, encodes isoform x.
    Source sequence(s)
    AL109915
    Conserved Domains (3) summary
    PHA03247
    Location:562830
    PHA03247; large tegument protein UL36; Provisional
    PRK12323
    Location:734836
    PRK12323; DNA polymerase III subunit gamma/tau
    pfam07651
    Location:24283
    ANTH; ANTH domain
  60. NM_001376735.1NP_001363664.1  clathrin coat assembly protein AP180 isoform y

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:611832
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:1225
    ANTH; ANTH domain
  61. NM_001376736.1NP_001363665.1  clathrin coat assembly protein AP180 isoform z

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:657827
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24269
    ANTH; ANTH domain
  62. NM_001376737.1NP_001363666.1  clathrin coat assembly protein AP180 isoform aa

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:588816
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  63. NM_001376738.1NP_001363667.1  clathrin coat assembly protein AP180 isoform bb

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:490660
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24283
    ANTH; ANTH domain
  64. NM_001376739.1NP_001363668.1  clathrin coat assembly protein AP180 isoform cc

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (2) summary
    PHA03247
    Location:476646
    PHA03247; large tegument protein UL36; Provisional
    pfam07651
    Location:24269
    ANTH; ANTH domain
  65. NM_001376740.1NP_001363669.1  clathrin coat assembly protein AP180 isoform dd

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (1) summary
    pfam07651
    Location:24283
    ANTH; ANTH domain
  66. NM_001376741.1NP_001363670.1  clathrin coat assembly protein AP180 isoform ee

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (1) summary
    pfam07651
    Location:24283
    ANTH; ANTH domain
  67. NM_001376742.1NP_001363671.1  clathrin coat assembly protein AP180 isoform ff

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Conserved Domains (1) summary
    pfam07651
    Location:24283
    ANTH; ANTH domain
  68. NM_014841.2NP_055656.1  clathrin coat assembly protein AP180 isoform a

    See identical proteins and their annotated locations for NP_055656.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (a). Variants 1 and 3 both encode the same isoform (a).
    Source sequence(s)
    AK289582, AL109915, BC044579, DB480068
    Consensus CDS
    CCDS47455.1
    UniProtKB/Swiss-Prot
    O60641
    Related
    ENSP00000400459.2, ENST00000439399.6
    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:595897
    Atrophin-1; Atrophin-1 family

RNA

  1. NR_164843.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL109915
  2. NR_164844.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL109915
  3. NR_164845.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL109915
  4. NR_164846.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL109915
    Related
    ENST00000518312.5

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    83552885..83709408 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011536271.1XP_011534573.1  clathrin coat assembly protein AP180 isoform X6

    Conserved Domains (2) summary
    pfam07651
    Location:21270
    ANTH; ANTH domain
    cl26464
    Location:581883
    Atrophin-1; Atrophin-1 family
  2. XM_017011586.1XP_016867075.1  clathrin coat assembly protein AP180 isoform X15

  3. XM_011536269.1XP_011534571.1  clathrin coat assembly protein AP180 isoform X3

    UniProtKB/TrEMBL
    E9PDG8
    Related
    ENSP00000429776.1, ENST00000521485.5
    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:671892
    Atrophin-1; Atrophin-1 family
  4. XM_006715615.1XP_006715678.1  clathrin coat assembly protein AP180 isoform X1

    See identical proteins and their annotated locations for XP_006715678.1

    UniProtKB/Swiss-Prot
    O60641
    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:595897
    Atrophin-1; Atrophin-1 family
  5. XM_017011587.1XP_016867076.1  clathrin coat assembly protein AP180 isoform X15

  6. XM_017011559.1XP_016867048.1  clathrin coat assembly protein AP180 isoform X3

    UniProtKB/TrEMBL
    E9PDG8
    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:671892
    Atrophin-1; Atrophin-1 family
  7. XM_017011558.1XP_016867047.1  clathrin coat assembly protein AP180 isoform X3

    UniProtKB/TrEMBL
    E9PDG8
    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:671892
    Atrophin-1; Atrophin-1 family
  8. XM_011536265.1XP_011534567.1  clathrin coat assembly protein AP180 isoform X1

    See identical proteins and their annotated locations for XP_011534567.1

    UniProtKB/Swiss-Prot
    O60641
    Related
    ENSP00000428215.1, ENST00000521743.5
    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:595897
    Atrophin-1; Atrophin-1 family
  9. XM_017011569.2XP_016867058.1  clathrin coat assembly protein AP180 isoform X8

  10. XM_017011566.2XP_016867055.1  clathrin coat assembly protein AP180 isoform X6

    Conserved Domains (2) summary
    pfam07651
    Location:21270
    ANTH; ANTH domain
    cl26464
    Location:581883
    Atrophin-1; Atrophin-1 family
  11. XM_017011567.1XP_016867056.1  clathrin coat assembly protein AP180 isoform X6

    Conserved Domains (2) summary
    pfam07651
    Location:21270
    ANTH; ANTH domain
    cl26464
    Location:581883
    Atrophin-1; Atrophin-1 family
  12. XM_017011584.2XP_016867073.1  clathrin coat assembly protein AP180 isoform X15

  13. XM_017011583.1XP_016867072.1  clathrin coat assembly protein AP180 isoform X15

  14. XM_017011557.2XP_016867046.1  clathrin coat assembly protein AP180 isoform X3

    UniProtKB/TrEMBL
    E9PDG8
    Related
    ENSP00000195649.6, ENST00000195649.10
    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:671892
    Atrophin-1; Atrophin-1 family
  15. XM_017011560.2XP_016867049.1  clathrin coat assembly protein AP180 isoform X3

    UniProtKB/TrEMBL
    E9PDG8
    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:671892
    Atrophin-1; Atrophin-1 family
  16. XM_005248770.5XP_005248827.1  clathrin coat assembly protein AP180 isoform X1

    See identical proteins and their annotated locations for XP_005248827.1

    UniProtKB/Swiss-Prot
    O60641
    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:595897
    Atrophin-1; Atrophin-1 family
  17. XM_017011585.2XP_016867074.1  clathrin coat assembly protein AP180 isoform X15

  18. XM_024446599.1XP_024302367.1  clathrin coat assembly protein AP180 isoform X6

    Conserved Domains (2) summary
    pfam07651
    Location:21270
    ANTH; ANTH domain
    cl26464
    Location:581883
    Atrophin-1; Atrophin-1 family
  19. XM_011536266.1XP_011534568.1  clathrin coat assembly protein AP180 isoform X1

    See identical proteins and their annotated locations for XP_011534568.1

    UniProtKB/Swiss-Prot
    O60641
    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:595897
    Atrophin-1; Atrophin-1 family
  20. XM_011536276.3XP_011534578.1  clathrin coat assembly protein AP180 isoform X14

    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:559861
    Atrophin-1; Atrophin-1 family
  21. XM_011536273.3XP_011534575.1  clathrin coat assembly protein AP180 isoform X9

    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:569871
    Atrophin-1; Atrophin-1 family
  22. XM_017011565.2XP_016867054.1  clathrin coat assembly protein AP180 isoform X5

    Conserved Domains (1) summary
    pfam07651
    Location:19284
    ANTH; ANTH domain
  23. XM_017011573.2XP_016867062.1  clathrin coat assembly protein AP180 isoform X9

    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:569871
    Atrophin-1; Atrophin-1 family
  24. XM_017011581.2XP_016867070.1  clathrin coat assembly protein AP180 isoform X14

    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:559861
    Atrophin-1; Atrophin-1 family
  25. XM_017011589.2XP_016867078.1  clathrin coat assembly protein AP180 isoform X16

  26. XM_017011562.2XP_016867051.1  clathrin coat assembly protein AP180 isoform X4

    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:590892
    Atrophin-1; Atrophin-1 family
  27. XM_017011580.2XP_016867069.1  clathrin coat assembly protein AP180 isoform X14

    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:559861
    Atrophin-1; Atrophin-1 family
  28. XM_017011570.2XP_016867059.1  clathrin coat assembly protein AP180 isoform X9

    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:569871
    Atrophin-1; Atrophin-1 family
  29. XM_017011572.2XP_016867061.1  clathrin coat assembly protein AP180 isoform X9

    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:569871
    Atrophin-1; Atrophin-1 family
  30. XM_017011564.2XP_016867053.1  clathrin coat assembly protein AP180 isoform X5

    Conserved Domains (1) summary
    pfam07651
    Location:19284
    ANTH; ANTH domain
  31. XM_017011571.2XP_016867060.1  clathrin coat assembly protein AP180 isoform X9

    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:569871
    Atrophin-1; Atrophin-1 family
  32. XM_017011582.2XP_016867071.1  clathrin coat assembly protein AP180 isoform X14

    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:559861
    Atrophin-1; Atrophin-1 family
  33. XM_024446600.1XP_024302368.1  clathrin coat assembly protein AP180 isoform X9

    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:569871
    Atrophin-1; Atrophin-1 family
  34. XM_017011577.1XP_016867066.1  clathrin coat assembly protein AP180 isoform X11

    Conserved Domains (1) summary
    pfam07651
    Location:19284
    ANTH; ANTH domain
  35. XM_011536275.2XP_011534577.1  clathrin coat assembly protein AP180 isoform X11

    Conserved Domains (1) summary
    pfam07651
    Location:19284
    ANTH; ANTH domain
  36. XM_017011579.2XP_016867068.1  clathrin coat assembly protein AP180 isoform X12

  37. XM_017011574.2XP_016867063.1  clathrin coat assembly protein AP180 isoform X10

    Conserved Domains (2) summary
    pfam07651
    Location:21284
    ANTH; ANTH domain
    cl26464
    Location:595875
    Atrophin-1; Atrophin-1 family
  38. XM_017011576.1XP_016867065.1  clathrin coat assembly protein AP180 isoform X11

    Conserved Domains (1) summary
    pfam07651
    Location:19284
    ANTH; ANTH domain
  39. XM_017011575.1XP_016867064.1  clathrin coat assembly protein AP180 isoform X11

    Conserved Domains (1) summary
    pfam07651
    Location:19284
    ANTH; ANTH domain
  40. XM_017011590.2XP_016867079.1  clathrin coat assembly protein AP180 isoform X17

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_026669.1: Suppressed sequence

    Description
    NR_026669.1: This RefSeq was permanently suppressed because it is now thought that this transcript does encode a protein.
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