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LRRC37A leucine rich repeat containing 37A [ Homo sapiens (human) ]

Gene ID: 9884, updated on 11-Sep-2019

Summary

Official Symbol
LRRC37Aprovided by HGNC
Official Full Name
leucine rich repeat containing 37Aprovided by HGNC
Primary source
HGNC:HGNC:29069
See related
Ensembl:ENSG00000176681 MIM:616555
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
LRRC37
Expression
Broad expression in testis (RPKM 14.7), bone marrow (RPKM 4.6) and 23 other tissues See more
Orthologs

Genomic context

See LRRC37A in Genome Data Viewer
Location:
17q21.31
Exon count:
14
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (46295131..46337794)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (44316744..44415160)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene chromosome 17 open reading frame 58 pseudogene Neighboring gene DND microRNA-mediated repression inhibitor 1 pseudogene 2 Neighboring gene ADP ribosylation factor like GTPase 17B Neighboring gene RNA, 7SL, cytoplasmic 656, pseudogene Neighboring gene uncharacterized protein FAM215A-like Neighboring gene Sharpr-MPRA regulatory region 7330

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide association study of d-amphetamine response in healthy volunteers identifies putative associations, including cadherin 13 (CDH13).
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0563, DKFZp686N1231

Gene Ontology Provided by GOA

Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
leucine-rich repeat-containing protein 37A

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014834.4NP_055649.4  leucine-rich repeat-containing protein 37A precursor

    See identical proteins and their annotated locations for NP_055649.4

    Status: VALIDATED

    Source sequence(s)
    AC005829, AC217777
    Consensus CDS
    CCDS11504.2
    UniProtKB/Swiss-Prot
    A6NMS7
    Related
    ENSP00000326324.5, ENST00000320254.5
    Conserved Domains (5) summary
    sd00031
    Location:891914
    LRR_1; leucine-rich repeat [structural motif]
    pfam12799
    Location:892929
    LRR_4; Leucine Rich repeats (2 copies)
    pfam13855
    Location:892949
    LRR_8; Leucine rich repeat
    pfam14914
    Location:14681613
    LRRC37AB_C; LRRC37A/B like protein 1 C-terminal domain
    pfam15779
    Location:561629
    LRRC37; Leucine-rich repeat-containing protein 37 family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    46295131..46337794
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NT_167251.2 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    413631..456611 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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