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URB1 URB1 ribosome biogenesis homolog [ Homo sapiens (human) ]

Gene ID: 9875, updated on 23-Nov-2021

Summary

Official Symbol
URB1provided by HGNC
Official Full Name
URB1 ribosome biogenesis homologprovided by HGNC
Primary source
HGNC:HGNC:17344
See related
Ensembl:ENSG00000142207 MIM:608865
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NPA1; C21orf108
Expression
Ubiquitous expression in testis (RPKM 5.5), endometrium (RPKM 5.1) and 25 other tissues See more
Orthologs
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Genomic context

See URB1 in Genome Data Viewer
Location:
21q22.11
Exon count:
39
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 21 NC_000021.9 (32311018..32393012, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (33683329..33765321, complement)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene MIS18 kinetochore protein A Neighboring gene MIS18A antisense RNA 1 Neighboring gene MRAP antisense RNA 1 Neighboring gene melanocortin 2 receptor accessory protein Neighboring gene Sharpr-MPRA regulatory region 9918 Neighboring gene small nucleolar RNA, H/ACA box 80A Neighboring gene URB1 antisense RNA 1 (head to head) Neighboring gene eva-1 homolog C Neighboring gene histone demethylase UTY-like

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0539

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables RNA binding HDA PubMed 
Component Evidence Code Pubs
located_in fibrillar center IDA
Inferred from Direct Assay
more info
 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
located_in nucleolus NAS
Non-traceable Author Statement
more info
PubMed 

General protein information

Preferred Names
nucleolar pre-ribosomal-associated protein 1
Names
URB1 ribosome biogenesis 1 homolog
nucleolar preribosomal-associated protein 1
nucleolar protein 254 kDa

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014825.3NP_055640.2  nucleolar pre-ribosomal-associated protein 1

    See identical proteins and their annotated locations for NP_055640.2

    Status: VALIDATED

    Source sequence(s)
    AP000266, AP000267, AP000268, AP000269
    Consensus CDS
    CCDS46645.1
    UniProtKB/Swiss-Prot
    O60287
    Related
    ENSP00000372199.3, ENST00000382751.4
    Conserved Domains (2) summary
    pfam11707
    Location:78393
    Npa1; Ribosome 60S biogenesis N-terminal
    pfam16201
    Location:16681857
    NopRA1; Nucleolar pre-ribosomal-associated protein 1

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p13 Primary Assembly

    Range
    32311018..32393012 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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