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Urb1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae) [ Mus musculus (house mouse) ]

Gene ID: 207932, updated on 1-Jul-2024

Summary

Official Symbol
Urb1provided by MGI
Official Full Name
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)provided by MGI
Primary source
MGI:MGI:2146468
See related
Ensembl:ENSMUSG00000039929 AllianceGenome:MGI:2146468
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA0539; 4921511H13Rik; 5730405K23Rik
Summary
Predicted to be involved in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in fibrillar center. Predicted to be active in nucleolus. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ. Orthologous to human URB1 (URB1 ribosome biogenesis homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 8.9), CNS E11.5 (RPKM 3.1) and 28 other tissues See more
Orthologs
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Genomic context

See Urb1 in Genome Data Viewer
Location:
16 C3.3; 16 51.92 cM
Exon count:
39
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (90548415..90607312, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (90751527..90810467, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr16:90727472-90727773 Neighboring gene predicted gene, 17518 Neighboring gene melanocortin 2 receptor accessory protein Neighboring gene STARR-seq mESC enhancer starr_41464 Neighboring gene STARR-positive B cell enhancer ABC_E1929 Neighboring gene eva-1 homolog C Neighboring gene predicted gene, 36363 Neighboring gene STARR-seq mESC enhancer starr_41466 Neighboring gene STARR-seq mESC enhancer starr_41467 Neighboring gene STARR-seq mESC enhancer starr_41468 Neighboring gene predicted gene, 53919 Neighboring gene cilia and flagella associate protien 298

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • KIAA0539

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in fibrillar center ISO
Inferred from Sequence Orthology
more info
 
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
nucleolar pre-ribosomal-associated protein 1
Names
nucleolar preribosomal-associated protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_029497.1NP_083773.1  nucleolar pre-ribosomal-associated protein 1

    Status: VALIDATED

    Source sequence(s)
    AK050735, AK220219, BB658427, BE943636, BU058447, BX522964, CD541646, CF534743, CK391060
    Consensus CDS
    CCDS49905.1
    UniProtKB/Swiss-Prot
    Q571H0, Q9CYN4
    UniProtKB/TrEMBL
    E9PU96
    Related
    ENSMUSP00000114717.2, ENSMUST00000140920.2
    Conserved Domains (2) summary
    pfam11707
    Location:78396
    Npa1; Ribosome 60S biogenesis N-terminal
    pfam16201
    Location:16701859
    NopRA1; Nucleolar pre-ribosomal-associated protein 1

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    90548415..90607312 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006522977.4XP_006523040.1  nucleolar pre-ribosomal-associated protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q571H0, Q9CYN4
    Conserved Domains (2) summary
    pfam11707
    Location:78396
    Npa1; Ribosome 60S biogenesis N-terminal
    pfam16201
    Location:16101799
    NopRA1; Nucleolar pre-ribosomal-associated protein 1