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Txndc9 thioredoxin domain containing 9 [ Mus musculus (house mouse) ]

Gene ID: 98258, updated on 2-Nov-2024

Summary

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Official Symbol
Txndc9provided by MGI
Official Full Name
thioredoxin domain containing 9provided by MGI
Primary source
MGI:MGI:2138153
See related
Ensembl:ENSMUSG00000058407 AllianceGenome:MGI:2138153
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
APACD
Summary
Predicted to be involved in microtubule cytoskeleton organization. Located in several cellular components, including centrosome; midbody; and nucleus. Orthologous to human TXNDC9 (thioredoxin domain containing 9). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 11.2), placenta adult (RPKM 8.5) and 26 other tissues See more
Orthologs
human all
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Genomic context

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See Txndc9 in Genome Data Viewer
Location:
1 B; 1 16.37 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (38022385..38036324, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (37983867..37997294, complement)

Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene lysozyme G-like 2 Neighboring gene STARR-seq mESC enhancer starr_00687 Neighboring gene lysozyme G-like 1 Neighboring gene STARR-positive B cell enhancer ABC_E3269 Neighboring gene STARR-positive B cell enhancer ABC_E10006 Neighboring gene eukaryotic translation initiation factor 5B Neighboring gene STARR-seq mESC enhancer starr_00688 Neighboring gene predicted gene, 34448 Neighboring gene STARR-seq mESC enhancer starr_00689 Neighboring gene STARR-seq mESC enhancer starr_00690 Neighboring gene REV1, DNA directed polymerase Neighboring gene STARR-seq mESC enhancer starr_00691

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Txndc9 Is Required for Meiotic Maturation of Mouse Oocytes. Ma F, et al. Biomed Res Int, 2017. PMID 28626760, Free PMC Article
  2. An evolutionarily conserved gene required for proper microtubule architecture in Caenorhabditis elegans. Ogawa S, et al. Genes Cells, 2004 Feb. PMID 15009089
  3. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
  4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  5. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article

See all (17) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
located_in centrosome IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm IDA
Inferred from Direct Assay
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in midbody IDA
Inferred from Direct Assay
more info
 PubMed 
located_in nucleus IDA
Inferred from Direct Assay
more info
 PubMed 

General protein information

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Preferred Names
thioredoxin domain-containing protein 9
Names
ATP binding protein associated with cell differentiation

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001417936.1 → NP_001404865.1  thioredoxin domain-containing protein 9 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC114583
    UniProtKB/Swiss-Prot
    Q3TKD2, Q9CQ79
    Related
    ENSMUSP00000141609.2, ENSMUST00000195247.6

  2. NM_001417937.1 → NP_001404866.1  thioredoxin domain-containing protein 9 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC114583
    UniProtKB/Swiss-Prot
    Q3TKD2, Q9CQ79
    Related
    ENSMUSP00000141595.2, ENSMUST00000195032.6

  3. NM_001417938.1 → NP_001404867.1  thioredoxin domain-containing protein 9 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC114583
    UniProtKB/TrEMBL
    A0A0A6YXY0
    Related
    ENSMUSP00000142188.2, ENSMUST00000193832.6

  4. NM_001417939.1 → NP_001404868.1  thioredoxin domain-containing protein 9 isoform c

    Status: VALIDATED

    Source sequence(s)
    AC114583
    UniProtKB/TrEMBL
    A0A0A6YVV3
    Related
    ENSMUSP00000141281.2, ENSMUST00000192960.6

  5. NM_001417940.1 → NP_001404869.1  thioredoxin domain-containing protein 9 isoform c

    Status: VALIDATED

    Source sequence(s)
    AC114583
    UniProtKB/TrEMBL
    A0A0A6YVV3

  6. NM_001417941.1 → NP_001404870.1  thioredoxin domain-containing protein 9 isoform c

    Status: VALIDATED

    Source sequence(s)
    AC114583
    UniProtKB/TrEMBL
    A0A0A6YVV3

  7. NM_172054.5 → NP_742051.1  thioredoxin domain-containing protein 9 isoform a

    See identical proteins and their annotated locations for NP_742051.1

    Status: VALIDATED

    Source sequence(s)
    AC114583
    Consensus CDS
    CCDS14898.1
    UniProtKB/Swiss-Prot
    Q3TKD2, Q9CQ79
    Related
    ENSMUSP00000125491.2, ENSMUST00000162031.8
    Conserved Domains (1) summary
    cd02989
    Location:68 → 180
    Phd_like_TxnDC9; Phosducin (Phd)-like family, Thioredoxin (TRX) domain containing protein 9 (TxnDC9) subfamily; composed of predominantly uncharacterized eukaryotic proteins, containing a TRX-like domain without the redox active CXXC motif. The gene name for the human ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000067.7 Reference GRCm39 C57BL/6J

    Range
    38022385..38036324 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9CQ79.1 GenPept UniProtKB/Swiss-Prot:Q9CQ79

Gene LinkOut

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