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Lrrc59 leucine rich repeat containing 59 [ Mus musculus (house mouse) ]

Gene ID: 98238, updated on 12-May-2024

Summary

Official Symbol
Lrrc59provided by MGI
Official Full Name
leucine rich repeat containing 59provided by MGI
Primary source
MGI:MGI:2138133
See related
Ensembl:ENSMUSG00000020869 AllianceGenome:MGI:2138133
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to be located in endoplasmic reticulum and mitochondrial nucleoid. Is expressed in several structures, including central nervous system and neural retina. Orthologous to human LRRC59 (leucine rich repeat containing 59). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in large intestine adult (RPKM 85.9), placenta adult (RPKM 76.8) and 28 other tissues See more
Orthologs
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Genomic context

See Lrrc59 in Genome Data Viewer
Location:
11 D; 11 58.9 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (94520603..94536049)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (94629777..94645223)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene radical S-adenosyl methionine domain containing 1 Neighboring gene acyl-CoA synthetase family member 2 Neighboring gene STARR-seq mESC enhancer starr_30470 Neighboring gene chondroadherin Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:94452878-94453079 Neighboring gene STARR-seq mESC enhancer starr_30472 Neighboring gene STARR-positive B cell enhancer mm9_chr11:94490883-94491183 Neighboring gene essential meiotic structure-specific endonuclease 1 Neighboring gene mitochondrial ribosomal protein L27 Neighboring gene xylosyltransferase II

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
  • Gene trapped (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in intracellular membrane-bounded organelle IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial nucleoid ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
leucine-rich repeat-containing protein 59

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133807.2NP_598568.1  leucine-rich repeat-containing protein 59

    See identical proteins and their annotated locations for NP_598568.1

    Status: VALIDATED

    Source sequence(s)
    AK159552, CX203638
    Consensus CDS
    CCDS25261.1
    UniProtKB/Swiss-Prot
    Q3TJ35, Q3TLC7, Q3TWT9, Q3TX86, Q922Q8
    Related
    ENSMUSP00000021239.7, ENSMUST00000021239.7
    Conserved Domains (3) summary
    PTZ00121
    Location:146228
    PTZ00121; MAEBL; Provisional
    COG4886
    Location:18120
    LRR; Leucine-rich repeat (LRR) protein [Transcription]
    sd00031
    Location:1940
    LRR_1; leucine-rich repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    94520603..94536049
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)