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H3c8 H3 clustered histone 8 [ Mus musculus (house mouse) ]

Gene ID: 97908, updated on 8-Feb-2024


Official Symbol
H3c8provided by MGI
Official Full Name
H3 clustered histone 8provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000099517 AllianceGenome:MGI:2145541
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
H3c1; H3c10; H3c11; H3.1-221; Hist1h3g
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. [provided by RefSeq, Aug 2015]
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Genomic context

13 A3.1; 13 9.77 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (23719588..23720079)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (23535418..23535909)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene H4 clustered histone 8 Neighboring gene STARR-positive B cell enhancer ABC_E4057 Neighboring gene H2A clustered histone 10 Neighboring gene STARR-positive B cell enhancer mm9_chr13:23627005-23627306 Neighboring gene STARR-positive B cell enhancer ABC_E4059 Neighboring gene STARR-positive B cell enhancer mm9_chr13:23636046-23636347 Neighboring gene H2B clustered histone 9 Neighboring gene H3 clustered histone 7

Genomic regions, transcripts, and products


Products Interactant Other Gene Complex Source Pubs Description

General gene information


Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
located_in nucleoplasm TAS
Traceable Author Statement
more info
part_of nucleosome ISO
Inferred from Sequence Orthology
more info
located_in nucleus ISO
Inferred from Sequence Orthology
more info
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info

General protein information

Preferred Names
histone H3.1
histone 1, H3g
histone cluster 1, H3g

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145073.2NP_659539.1  histone H3.1

    See identical proteins and their annotated locations for NP_659539.1

    Status: REVIEWED

    Source sequence(s)
    Consensus CDS
    P68433, Q05A97, Q3B7Z8, Q3B7Z9, Q5T009
    ENSMUSP00000079670.6, ENSMUST00000080859.8
    Conserved Domains (1) summary
    PTZ00018; histone H3; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000079.7 Reference GRCm39 C57BL/6J

    GenBank, FASTA, Sequence Viewer (Graphics)