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DLGAP5 DLG associated protein 5 [ Homo sapiens (human) ]

Gene ID: 9787, updated on 13-Mar-2020

Summary

Official Symbol
DLGAP5provided by HGNC
Official Full Name
DLG associated protein 5provided by HGNC
Primary source
HGNC:HGNC:16864
See related
Ensembl:ENSG00000126787 MIM:617859
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DLG7; HURP
Expression
Biased expression in bone marrow (RPKM 9.4), testis (RPKM 9.1) and 12 other tissues See more
Orthologs

Genomic context

See DLGAP5 in Genome Data Viewer
Location:
14q22.3
Exon count:
21
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (55148130..55191585, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (55614834..55658396, complement)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 8345 Neighboring gene galectin 3 Neighboring gene uncharacterized LOC105370508 Neighboring gene uncharacterized LOC107984708

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0008

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
cell IEA
Inferred from Electronic Annotation
more info
 
centriolar satellite IDA
Inferred from Direct Assay
more info
 
cytosol IDA
Inferred from Direct Assay
more info
 
cytosol TAS
Traceable Author Statement
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
spindle pole centrosome IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
disks large-associated protein 5
Names
DAP-5
discs large homolog associated protein 5
discs, large homolog 7
disks large-associated protein DLG7
hepatoma up-regulated protein

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001146015.2NP_001139487.1  disks large-associated protein 5 isoform b

    See identical proteins and their annotated locations for NP_001139487.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) includes an alternate exon in the 3' coding region, compared to variant 1, that causes a frameshift. The resulting protein (isoform b) has a distinct C-terminus, compared to isoform a.
    Source sequence(s)
    AK299338, BM788630, BX248255
    Consensus CDS
    CCDS53897.1
    UniProtKB/Swiss-Prot
    Q15398
    Related
    ENSP00000378815.2, ENST00000395425.6
    Conserved Domains (1) summary
    pfam03359
    Location:432599
    GKAP; Guanylate-kinase-associated protein (GKAP) protein
  2. NM_014750.5NP_055565.3  disks large-associated protein 5 isoform a

    See identical proteins and their annotated locations for NP_055565.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shorter transcript but encodes the longer isoform (a).
    Source sequence(s)
    AB076695, BC010658
    Consensus CDS
    CCDS9723.1
    UniProtKB/Swiss-Prot
    Q15398
    Related
    ENSP00000247191.2, ENST00000247191.7
    Conserved Domains (1) summary
    pfam03359
    Location:432599
    GKAP; Guanylate-kinase-associated protein (GKAP) protein

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    55148130..55191585 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017021840.2XP_016877329.1  disks large-associated protein 5 isoform X1

    UniProtKB/Swiss-Prot
    Q15398
    Conserved Domains (1) summary
    pfam03359
    Location:432599
    GKAP; Guanylate-kinase-associated protein (GKAP) protein
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