NEW
Try the new Transcript table
These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in
this section to the one reported in Genomic regions,
transcripts, and products above.
mRNA and Protein(s)
-
NM_014641.3 → NP_055456.2  mediator of DNA damage checkpoint protein 1
See identical proteins and their annotated locations for NP_055456.2
Status: REVIEWED
- Source sequence(s)
-
AL662797, BU621433, D79992, EF177823
- Consensus CDS
-
CCDS34384.1
- UniProtKB/Swiss-Prot
- Q14676, Q96QC2
- UniProtKB/TrEMBL
- A0A1U9XBC1, A1Z5I9
- Related
- ENSP00000365588.3, ENST00000376406.8
- Conserved Domains (5) summary
-
- pfam00498
Location:55 → 110
- FHA; FHA domain
- cl00038
Location:1882 → 1968
- BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
- cl25732
Location:822 → 962
- SMC_N; RecF/RecN/SMC N terminal domain
- cl25751
Location:943 → 1376
- DUF4045; Domain of unknown function (DUF4045)
- cl26464
Location:1227 → 1757
- Atrophin-1; Atrophin-1 family
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as
RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate
assemblies. Model RNAs and proteins are also reported here.
Reference GRCh38.p14 Primary Assembly
Genomic
-
NC_000006.12Â Reference GRCh38.p14 Primary Assembly
- Range
-
30699807..30717281 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
mRNA and Protein(s)
-
XM_047419589.1 → XP_047275545.1  mediator of DNA damage checkpoint protein 1 isoform X11
-
XM_047419588.1 → XP_047275544.1  mediator of DNA damage checkpoint protein 1 isoform X10
-
XM_047419586.1 → XP_047275542.1  mediator of DNA damage checkpoint protein 1 isoform X7
-
XM_005249494.6 → XP_005249551.1  mediator of DNA damage checkpoint protein 1 isoform X3
See identical proteins and their annotated locations for XP_005249551.1
- UniProtKB/Swiss-Prot
- Q14676, Q96QC2
- UniProtKB/TrEMBL
-
A0A1U9XBC1
- Conserved Domains (5) summary
-
- pfam00498
Location:55 → 110
- FHA; FHA domain
- cl00038
Location:1882 → 1968
- BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
- cl25732
Location:822 → 962
- SMC_N; RecF/RecN/SMC N terminal domain
- cl25751
Location:943 → 1376
- DUF4045; Domain of unknown function (DUF4045)
- cl26464
Location:1227 → 1757
- Atrophin-1; Atrophin-1 family
-
XM_047419582.1 → XP_047275538.1  mediator of DNA damage checkpoint protein 1 isoform X3
- UniProtKB/Swiss-Prot
-
Q96QC2
- UniProtKB/TrEMBL
-
A0A1U9XBC1
-
XM_047419584.1 → XP_047275540.1  mediator of DNA damage checkpoint protein 1 isoform X3
- UniProtKB/Swiss-Prot
-
Q96QC2
- UniProtKB/TrEMBL
-
A0A1U9XBC1
-
XM_017011522.3 → XP_016867011.1  mediator of DNA damage checkpoint protein 1 isoform X9
-
XM_047419585.1 → XP_047275541.1  mediator of DNA damage checkpoint protein 1 isoform X6
-
XM_047419581.1 → XP_047275537.1  mediator of DNA damage checkpoint protein 1 isoform X2
-
XM_047419587.1 → XP_047275543.1  mediator of DNA damage checkpoint protein 1 isoform X8
-
XM_047419580.1 → XP_047275536.1  mediator of DNA damage checkpoint protein 1 isoform X1
-
XM_047419583.1 → XP_047275539.1  mediator of DNA damage checkpoint protein 1 isoform X3
- UniProtKB/Swiss-Prot
-
Q96QC2
- UniProtKB/TrEMBL
-
A0A1U9XBC1
-
XM_011515003.4 → XP_011513305.1  mediator of DNA damage checkpoint protein 1 isoform X3
See identical proteins and their annotated locations for XP_011513305.1
- UniProtKB/Swiss-Prot
- Q14676, Q96QC2
- UniProtKB/TrEMBL
-
A0A1U9XBC1
- Conserved Domains (5) summary
-
- pfam00498
Location:55 → 110
- FHA; FHA domain
- cl00038
Location:1882 → 1968
- BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
- cl25732
Location:822 → 962
- SMC_N; RecF/RecN/SMC N terminal domain
- cl25751
Location:943 → 1376
- DUF4045; Domain of unknown function (DUF4045)
- cl26464
Location:1227 → 1757
- Atrophin-1; Atrophin-1 family
-
XM_005249498.5 → XP_005249555.1  mediator of DNA damage checkpoint protein 1 isoform X8
See identical proteins and their annotated locations for XP_005249555.1
- Conserved Domains (2) summary
-
- cd00027
Location:1663 → 1715
- BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
- pfam00498
Location:76 → 144
- FHA; FHA domain
-
XM_005249497.5 → XP_005249554.1  mediator of DNA damage checkpoint protein 1 isoform X5
See identical proteins and their annotated locations for XP_005249554.1
- Conserved Domains (2) summary
-
- cd00027
Location:1737 → 1789
- BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
- pfam00498
Location:76 → 144
- FHA; FHA domain
-
XM_005249492.3 → XP_005249549.1  mediator of DNA damage checkpoint protein 1 isoform X1
See identical proteins and their annotated locations for XP_005249549.1
- Conserved Domains (6) summary
-
- PTZ00449
Location:964 → 1397
- PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
- PHA03247
Location:1248 → 1778
- PHA03247; large tegument protein UL36; Provisional
- cd00060
Location:54 → 144
- FHA; Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins ...
- TIGR02169
Location:843 → 983
- SMC_prok_A; chromosome segregation protein SMC, primarily archaeal type
- cd17744
Location:1914 → 1984
- BRCT_MDC1_rpt1; first BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins
- cd18441
Location:2016 → 2096
- BRCT_MDC1_rpt2; second BRCT domain of mediator of DNA damage checkpoint protein 1 (MDC1) and similar proteins
-
XM_011515004.4 → XP_011513306.1  mediator of DNA damage checkpoint protein 1 isoform X4
See identical proteins and their annotated locations for XP_011513306.1
- Conserved Domains (1) summary
-
- cd00027
Location:1778 → 1830
- BRCT; Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo ...
Reference GRCh38.p14 ALT_REF_LOCI_1
Genomic
-
NT_167244.2Â Reference GRCh38.p14 ALT_REF_LOCI_1
- Range
-
2029312..2046785 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Reference GRCh38.p14 ALT_REF_LOCI_2
Genomic
-
NT_113891.3Â Reference GRCh38.p14 ALT_REF_LOCI_2
- Range
-
2179547..2197021 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Reference GRCh38.p14 ALT_REF_LOCI_3
Genomic
-
NT_167245.2Â Reference GRCh38.p14 ALT_REF_LOCI_3
- Range
-
1955659..1973132 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Reference GRCh38.p14 ALT_REF_LOCI_4
Genomic
-
NT_167246.2Â Reference GRCh38.p14 ALT_REF_LOCI_4
- Range
-
2010059..2027532 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Reference GRCh38.p14 ALT_REF_LOCI_5
Genomic
-
NT_167247.2Â Reference GRCh38.p14 ALT_REF_LOCI_5
- Range
-
2043883..2061356 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Reference GRCh38.p14 ALT_REF_LOCI_6
Genomic
-
NT_167248.2Â Reference GRCh38.p14 ALT_REF_LOCI_6
- Range
-
1954920..1972393 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Reference GRCh38.p14 ALT_REF_LOCI_7
Genomic
-
NT_167249.2Â Reference GRCh38.p14 ALT_REF_LOCI_7
- Range
-
2000593..2018067 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate T2T-CHM13v2.0
Genomic
-
NC_060930.1Â Alternate T2T-CHM13v2.0
- Range
-
30564011..30581484 complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)