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tcyJ cystine ABC transporter periplasmic binding protein [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948833, updated on 4-Feb-2026
Official Symbol
tcyJ
Official Full Name
cystine ABC transporter periplasmic binding protein
Primary source
ECOCYC:G7039
Locus tag
b1920
See related
ASAP:ABE-0006392
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK1919; fliY; ssi7; yzzR
Summary
FliY is a periplasmic cystine-binding protein . [More information is available at EcoCyc: G7039].
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Sequence:
NC_000913.3 (1999585..2000385, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene cystine ABC transporter ATP binding subunit Neighboring gene cystine ABC transporter membrane subunit Neighboring gene D-cysteine desulfhydrase Neighboring gene DNA-binding transcriptional regulator FliZ Neighboring gene RNA polymerase sigma factor FliA

Genomic Sequence:
NC_000913.3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Amino acid composition and N-terminal sequence of purified cystine binding protein of Escherichia coli. Butler JD, et al. Life Sci, 1993. PMID 8450713
  2. The bspA locus of Lactobacillus fermentum BR11 encodes an L-cystine uptake system. Turner MS, et al. J Bacteriol, 1999 Apr. PMID 10094698, Free PMC Article
  3. Structure and expression of the fliA operon of Salmonella typhimurium. Ikebe T, et al. Microbiology (Reading), 1999 Jun. PMID 10411266
  4. Assays for CheC, FliY, and CheX as representatives of response regulator phosphatases. Muff TJ, et al. Methods Enzymol, 2007. PMID 17609139
  5. Escherichia coli fliAZY operon. Mytelka DS, et al. J Bacteriol, 1996 Jan. PMID 8550423, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. analysis of integration and expression at four candidate loci, fliD, fliS, fliT, and fliY, of the E. coli flagellar region 3a
    Title: Escherichia coli flagellar genes as target sites for integration and expression of genetic circuits.
  2. N-terminus verified by Edman degradation on mature peptide
    Title: '98 Escherichia coli SWISS-2DPAGE database update.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by EcoCyc

Function Evidence Code Pubs
enables L-cystine transmembrane transporter activity EXP
Inferred from Experiment
more info
 PubMed 
enables L-cystine transmembrane transporter activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables amino acid binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables ligand-gated monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within L-cystine transport EXP
Inferred from Experiment
more info
 PubMed 
acts_upstream_of_or_within L-cystine transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in amino acid transport IEA
Inferred from Electronic Annotation
more info
  
involved_in cysteine transmembrane transport NAS
Non-traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within diaminopimelate transport IGI
Inferred from Genetic Interaction
more info
 PubMed 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sulfur utilization IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in outer membrane-bounded periplasmic space IDA
Inferred from Direct Assay
more info
 PubMed 
located_in outer membrane-bounded periplasmic space IEA
Inferred from Electronic Annotation
more info
  
located_in periplasmic space IEA
Inferred from Electronic Annotation
more info
  
Preferred Names
cystine ABC transporter periplasmic binding protein
NP_416430.1

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    1999585..2000385 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_416430.1 cystine ABC transporter periplasmic binding protein

    See identical proteins and their annotated locations for NP_416430.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A0A7A7F856, A0A8S7JYS5
    Conserved Domains (1) summary
    PRK11260
    Location:1 → 266
    PRK11260; cystine ABC transporter substrate-binding protein
Nucleotide Protein
Heading Accession and Version

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