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TTC30A tetratricopeptide repeat domain 30A [ Homo sapiens (human) ]

Gene ID: 92104, updated on 15-Jun-2019

Summary

Official Symbol
TTC30Aprovided by HGNC
Official Full Name
tetratricopeptide repeat domain 30Aprovided by HGNC
Primary source
HGNC:HGNC:25853
See related
Ensembl:ENSG00000197557
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IFT70A; TTC30B
Orthologs

Genomic context

See TTC30A in Genome Data Viewer
Location:
2q31.2
Exon count:
1
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 2 NC_000002.12 (177614298..177618966, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (178479026..178483694, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene alkylglycerone phosphate synthase Neighboring gene uncharacterized LOC105373762 Neighboring gene tetratricopeptide repeat domain 30B Neighboring gene uncharacterized LOC105373764 Neighboring gene phosphodiesterase 11A Neighboring gene apoptosis inhibitor 5 pseudogene 2

Genomic regions, transcripts, and products

HIV-1 interactions

Protein interactions

Protein Gene Interaction Pubs
Vif vif HIV-1 Vif downregulates the expression of tetratricopeptide repeat domain 30A (TTC30A) in Vif-expression T cells PubMed

Go to the HIV-1, Human Interaction Database

Pathways from BioSystems

  • Cilium Assembly, organism-specific biosystem (from REACTOME)
    Cilium Assembly, organism-specific biosystemCilia are membrane covered organelles that extend from the surface of eukaryotic cells. Cilia may be motile, such as respiratory cilia) or non-motile (such as the primary cilium) and are distinguishe...
  • Intraflagellar transport, organism-specific biosystem (from REACTOME)
    Intraflagellar transport, organism-specific biosystemIntraflagellar transport (IFT) is a motor-based process that controls the anterograde and retrograde transport of large protein complexes, ciliary cargo and structural components along the ciliary ax...
  • Organelle biogenesis and maintenance, organism-specific biosystem (from REACTOME)
    Organelle biogenesis and maintenance, organism-specific biosystemThis module describes the biogenesis of organelles. Organelles are subcellular structures of distinctive morphology and function. The organelles of human cells include: mitochondria, endoplasmic reti...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ13946, FLJ77601

Gene Ontology Provided by GOA

Function Evidence Code Pubs
intraciliary transport particle B binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
intraciliary transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
axonemal microtubule IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
intraciliary transport particle B IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
tetratricopeptide repeat protein 30A
Names
TPR repeat protein 30A
TPR repeat protein 30B
Tetratricopeptide repeat protein 30B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152275.4NP_689488.3  tetratricopeptide repeat protein 30A

    See identical proteins and their annotated locations for NP_689488.3

    Status: VALIDATED

    Source sequence(s)
    AC073834, BC042848, BM684657
    Consensus CDS
    CCDS2276.1
    UniProtKB/Swiss-Prot
    Q86WT1
    Related
    ENSP00000347915.4, ENST00000355689.6
    Conserved Domains (3) summary
    sd00006
    Location:159182
    TPR; TPR repeat [structural motif]
    pfam13414
    Location:159216
    TPR_11; TPR repeat
    pfam13432
    Location:1676
    TPR_16; Tetratricopeptide repeat

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    177612999..177618742 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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