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WDR20 WD repeat domain 20 [ Homo sapiens (human) ]

Gene ID: 91833, updated on 13-Mar-2020

Summary

Official Symbol
WDR20provided by HGNC
Official Full Name
WD repeat domain 20provided by HGNC
Primary source
HGNC:HGNC:19667
See related
Ensembl:ENSG00000140153 MIM:617741
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
DMR
Summary
This gene encodes a WD repeat-containing protein that functions to preserve and regulate the activity of the USP12-UAF1 deubiquitinating enzyme complex. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2011]
Expression
Ubiquitous expression in testis (RPKM 5.3), thyroid (RPKM 3.2) and 25 other tissues See more
Orthologs

Genomic context

See WDR20 in Genome Data Viewer
Location:
14q32.31
Exon count:
13
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 14 NC_000014.9 (102139423..102224686)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (102606189..102690010)

Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene dynein cytoplasmic 1 heavy chain 1 Neighboring gene uncharacterized LOC107984661 Neighboring gene RNA, 7SL, cytoplasmic 472, pseudogene Neighboring gene heat shock protein 90 alpha family class A member 1 Neighboring gene uncharacterized LOC105370677 Neighboring gene MOK protein kinase Neighboring gene tRNA-Ile (anticodon AAT) 5-4 Neighboring gene zinc finger protein 839

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ27314, FLJ33659, MGC33177, MGC33183, DKFZp686B2131

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
protein deubiquitination TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
nucleoplasm TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
WD repeat-containing protein 20

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001242414.2NP_001229343.1  WD repeat-containing protein 20 isoform 4

    See identical proteins and their annotated locations for NP_001229343.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) differs in the central and 3' coding regions, and in the 3' UTR, compared to variant 1. The encoded isoform (4) has a distinct and significantly shorter C-terminus, compared to isoform 1. Variants 4 and 37 both encode the same isoform (4).
    Source sequence(s)
    AL832242, BC028387, BP363522
    Consensus CDS
    CCDS55942.1
    UniProtKB/Swiss-Prot
    Q8TBZ3
    Related
    ENSP00000299135.6, ENST00000299135.6
  2. NM_001242415.2NP_001229344.1  WD repeat-containing protein 20 isoform 5

    See identical proteins and their annotated locations for NP_001229344.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (5) has a distinct and significantly shorter C-terminus, compared to isoform 1.
    Source sequence(s)
    AL359402, BC030654
    Consensus CDS
    CCDS55944.1
    UniProtKB/Swiss-Prot
    Q8TBZ3
    Related
    ENSP00000314209.5, ENST00000322340.9
  3. NM_001242416.2NP_001229345.1  WD repeat-containing protein 20 isoform 6

    See identical proteins and their annotated locations for NP_001229345.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (6) that is shorter than isoform 1.
    Source sequence(s)
    AF327354, AK225852, AL832242
    Consensus CDS
    CCDS55945.1
    UniProtKB/Swiss-Prot
    Q8TBZ3
    Related
    ENSP00000450636.1, ENST00000556807.1
    Conserved Domains (2) summary
    sd00039
    Location:92157
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:88253
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  4. NM_001242417.2NP_001229346.1  WD repeat-containing protein 20 isoform 7

    Status: REVIEWED

    Description
    Transcript Variant: This variant (7) differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (7) has a distinct and longer C-terminus, compared to isoform 1.
    Source sequence(s)
    AK297727, BC028387, BP363522
    Consensus CDS
    CCDS55943.1
    UniProtKB/Swiss-Prot
    Q8TBZ3
    Related
    ENSP00000406084.2, ENST00000454394.2
    Conserved Domains (2) summary
    sd00039
    Location:184249
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:180345
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  5. NM_001242418.2NP_001229347.1  WD repeat-containing protein 20 isoform 8

    See identical proteins and their annotated locations for NP_001229347.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (8) uses an alternate in-frame splice site in the 5' coding region, and differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (8) is the same length but has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AL832500, BC028387, BP363522
    UniProtKB/Swiss-Prot
    Q8TBZ3
    UniProtKB/TrEMBL
    Q5JPH5
    Conserved Domains (3) summary
    COG2319
    Location:159401
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:114155
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:161326
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  6. NM_001320130.2NP_001307059.1  WD repeat-containing protein 20 isoform 10

    Status: REVIEWED

    Description
    Transcript Variant: This variant (10) lacks an exon in the coding region, compared to variant 1. The encoded isoform (10) is shorter, compared to isoform 1.
    Source sequence(s)
    AL359402, BM707311, BP363522, DR423616
  7. NM_001330228.2NP_001317157.1  WD repeat-containing protein 20 isoform 11

    Status: REVIEWED

    Description
    Transcript Variant: This variant (11) contains an alternate in-frame exon in the 5' coding region compared to variant 1, and encodes the longest isoform (11).
    Source sequence(s)
    AL133223, AL359402
    Consensus CDS
    CCDS81853.1
    UniProtKB/TrEMBL
    A0A088AWN2
    Related
    ENSP00000395793.3, ENST00000424963.6
  8. NM_001353656.2NP_001340585.1  WD repeat-containing protein 20 isoform 12

    Status: REVIEWED

    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:102143
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:149314
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  9. NM_001353657.2NP_001340586.1  WD repeat-containing protein 20 isoform 13

    Status: REVIEWED

    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:102143
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:149314
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  10. NM_001353658.2NP_001340587.1  WD repeat-containing protein 20 isoform 14

    Status: REVIEWED

    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:103168
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:99264
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  11. NM_001353659.2NP_001340588.1  WD repeat-containing protein 20 isoform 15

    Status: REVIEWED

    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:104169
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:100265
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  12. NM_001353660.2NP_001340589.1  WD repeat-containing protein 20 isoform 16

    Status: REVIEWED

    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:103168
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:99264
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  13. NM_001353661.2NP_001340590.1  WD repeat-containing protein 20 isoform 17

    Status: REVIEWED

    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:2287
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:18183
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  14. NM_001353662.2NP_001340591.1  WD repeat-containing protein 20 isoform 18

    Status: REVIEWED

    Description
    Transcript Variant: This variant (18), as well as variants 19-22, encodes isoform 18.
    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  15. NM_001353663.2NP_001340592.1  WD repeat-containing protein 20 isoform 18

    Status: REVIEWED

    Description
    Transcript Variant: This variant (19), as well as variants 18 and 20-22, encodes isoform 18.
    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  16. NM_001353664.2NP_001340593.1  WD repeat-containing protein 20 isoform 18

    Status: REVIEWED

    Description
    Transcript Variant: This variant (20), as well as variants 18, 19, 21, and 22, encodes isoform 18.
    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  17. NM_001353665.2NP_001340594.1  WD repeat-containing protein 20 isoform 18

    Status: REVIEWED

    Description
    Transcript Variant: This variant (21), as well as variants 18-20 and 22, encodes isoform 18.
    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  18. NM_001353666.2NP_001340595.1  WD repeat-containing protein 20 isoform 18

    Status: REVIEWED

    Description
    Transcript Variant: This variant (22), as well as variants 18-21, encodes isoform 18.
    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl29593
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  19. NM_001353667.2NP_001340596.1  WD repeat-containing protein 20 isoform 19

    Status: REVIEWED

    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  20. NM_001353668.2NP_001340597.1  WD repeat-containing protein 20 isoform 20

    Status: REVIEWED

    Description
    Transcript Variant: This variant (24), as well as variants 25-30, encodes isoform 20.
    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  21. NM_001353669.2NP_001340598.1  WD repeat-containing protein 20 isoform 20

    Status: REVIEWED

    Description
    Transcript Variant: This variant (25), as well as variants 24 and 26-30, encodes isoform 20.
    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  22. NM_001353670.2NP_001340599.1  WD repeat-containing protein 20 isoform 20

    Status: REVIEWED

    Description
    Transcript Variant: This variant (26), as well as variants 24, 25, and 27-30, encodes isoform 20.
    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  23. NM_001353671.2NP_001340600.1  WD repeat-containing protein 20 isoform 20

    Status: REVIEWED

    Description
    Transcript Variant: This variant (27), as well as variants 24-26 and 28-30, encodes isoform 20.
    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  24. NM_001353672.2NP_001340601.1  WD repeat-containing protein 20 isoform 20

    Status: REVIEWED

    Description
    Transcript Variant: This variant (28), as well as variants 24-27, 29, and 30, encodes isoform 20.
    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  25. NM_001353673.2NP_001340602.1  WD repeat-containing protein 20 isoform 20

    Status: REVIEWED

    Description
    Transcript Variant: This variant (29), as well as variants 24-28 and 30, encodes isoform 20.
    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  26. NM_001353674.2NP_001340603.1  WD repeat-containing protein 20 isoform 20

    Status: REVIEWED

    Description
    Transcript Variant: This variant (30), as well as variants 24-29, encodes isoform 20.
    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  27. NM_001353675.2NP_001340604.1  WD repeat-containing protein 20 isoform 21

    Status: REVIEWED

    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:942
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:262
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  28. NM_001353676.2NP_001340605.1  WD repeat-containing protein 20 isoform 22

    Status: REVIEWED

    Description
    Transcript Variant: This variant (32), as well as variants 33 and 34, encodes isoform 22.
    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:942
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:262
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  29. NM_001353677.2NP_001340606.1  WD repeat-containing protein 20 isoform 22

    Status: REVIEWED

    Description
    Transcript Variant: This variant (33), as well as variants 32 and 34, encodes isoform 22.
    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:942
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:262
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  30. NM_001353678.2NP_001340607.1  WD repeat-containing protein 20 isoform 22

    Status: REVIEWED

    Description
    Transcript Variant: This variant (34), as well as variants 32 and 33, encodes isoform 22.
    Source sequence(s)
    AL133223, AL359402
    Conserved Domains (2) summary
    sd00039
    Location:942
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:262
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  31. NM_001353679.2NP_001340608.1  WD repeat-containing protein 20 isoform 23

    Status: REVIEWED

    Source sequence(s)
    AL133223, AL359402
  32. NM_001353680.2NP_001340609.1  WD repeat-containing protein 20 isoform 24

    Status: REVIEWED

    Source sequence(s)
    AL133223, AL359402
  33. NM_001353681.2NP_001340610.1  WD repeat-containing protein 20 isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (37), as well as variant 4, encodes isoform 4.
    Source sequence(s)
    AL133223, AL359402
    Consensus CDS
    CCDS55942.1
  34. NM_144574.4NP_653175.2  WD repeat-containing protein 20 isoform 2

    See identical proteins and their annotated locations for NP_653175.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2) has a distinct and shorter C-terminus, compared to isoform 1.
    Source sequence(s)
    AL832242, BC028387
    Consensus CDS
    CCDS9969.1
    UniProtKB/Swiss-Prot
    Q8TBZ3
    Related
    ENSP00000341037.3, ENST00000342702.7
    Conserved Domains (2) summary
    sd00039
    Location:102143
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:149314
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  35. NM_181291.3NP_851808.1  WD repeat-containing protein 20 isoform 1

    See identical proteins and their annotated locations for NP_851808.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    AF327354, AK225852, AL832242, BP363522
    Consensus CDS
    CCDS9968.1
    UniProtKB/Swiss-Prot
    Q8TBZ3
    Related
    ENSP00000335434.5, ENST00000335263.9
    Conserved Domains (2) summary
    sd00039
    Location:102143
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:149314
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  36. NM_181308.3NP_851825.1  WD repeat-containing protein 20 isoform 3

    See identical proteins and their annotated locations for NP_851825.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region and differs in the 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (3) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    BC028387, BP363522, BX248274
    Consensus CDS
    CCDS9970.1
    UniProtKB/Swiss-Prot
    Q8TBZ3
    Related
    ENSP00000451633.2, ENST00000556511.2
    Conserved Domains (2) summary
    sd00039
    Location:92157
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:88253
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RNA

  1. NR_038354.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (9) includes an additional exon in the central region, and alternate exon structure in the 3' region, compared to variant 1. This variant is represented as non-coding because the use of the supported translational start codon, as found in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    AK090580, BC028387
  2. NR_148510.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AL133223, AL359402
  3. NR_148511.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AL133223, AL359402

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000014.9 Reference GRCh38.p13 Primary Assembly

    Range
    102139423..102224686
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024449743.1XP_024305511.1  WD repeat-containing protein 20 isoform X13

    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. XM_024449742.1XP_024305510.1  WD repeat-containing protein 20 isoform X13

    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. XM_011537352.3XP_011535654.1  WD repeat-containing protein 20 isoform X15

  4. XM_011537353.3XP_011535655.1  WD repeat-containing protein 20 isoform X16

  5. XM_011537356.3XP_011535658.1  WD repeat-containing protein 20 isoform X17

  6. XM_006720308.1XP_006720371.1  WD repeat-containing protein 20 isoform X11

    See identical proteins and their annotated locations for XP_006720371.1

    Conserved Domains (3) summary
    COG2319
    Location:78328
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:92157
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:88253
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  7. XM_011537358.3XP_011535660.1  WD repeat-containing protein 20 isoform X18

  8. XM_011537339.2XP_011535641.1  WD repeat-containing protein 20 isoform X5

    Conserved Domains (3) summary
    COG2319
    Location:190432
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:196261
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:192357
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  9. XM_011537335.2XP_011535637.1  WD repeat-containing protein 20 isoform X1

    Conserved Domains (3) summary
    COG2319
    Location:190432
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:196261
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:192357
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  10. XM_011537337.2XP_011535639.1  WD repeat-containing protein 20 isoform X3

    Conserved Domains (3) summary
    COG2319
    Location:190432
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:196261
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:192357
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  11. XM_011537340.3XP_011535642.1  WD repeat-containing protein 20 isoform X6

    Conserved Domains (3) summary
    COG2319
    Location:190432
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:196261
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:192357
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  12. XM_011537336.2XP_011535638.1  WD repeat-containing protein 20 isoform X2

    Conserved Domains (3) summary
    COG2319
    Location:190432
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:196261
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:192357
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  13. XM_017021767.1XP_016877256.1  WD repeat-containing protein 20 isoform X8

  14. XM_011537341.2XP_011535643.1  WD repeat-containing protein 20 isoform X7

    Conserved Domains (3) summary
    COG2319
    Location:159401
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:114155
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:161326
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  15. XM_006720309.1XP_006720372.1  WD repeat-containing protein 20 isoform X13

    See identical proteins and their annotated locations for XP_006720372.1

    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  16. XM_011537338.1XP_011535640.1  WD repeat-containing protein 20 isoform X4

    See identical proteins and their annotated locations for XP_011535640.1

    Conserved Domains (3) summary
    COG2319
    Location:178420
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:184249
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:180345
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  17. XM_017021785.1XP_016877274.1  WD repeat-containing protein 20 isoform X19

    Conserved Domains (3) summary
    COG2319
    Location:178420
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:184249
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:180345
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  18. XM_006720313.2XP_006720376.1  WD repeat-containing protein 20 isoform X14

    See identical proteins and their annotated locations for XP_006720376.1

    Conserved Domains (2) summary
    sd00039
    Location:942
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:262
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  19. XM_017021774.1XP_016877263.1  WD repeat-containing protein 20 isoform X13

    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  20. XM_017021772.1XP_016877261.1  WD repeat-containing protein 20 isoform X13

    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  21. XM_017021781.1XP_016877270.1  WD repeat-containing protein 20 isoform X14

    Conserved Domains (2) summary
    sd00039
    Location:942
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:262
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  22. XM_011537343.1XP_011535645.1  WD repeat-containing protein 20 isoform X9

    Conserved Domains (3) summary
    COG2319
    Location:128370
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:134199
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:130295
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  23. XM_011537345.2XP_011535647.1  WD repeat-containing protein 20 isoform X12

    Conserved Domains (3) summary
    COG2319
    Location:4265
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:2994
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:25190
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  24. XM_006720311.1XP_006720374.1  WD repeat-containing protein 20 isoform X13

    See identical proteins and their annotated locations for XP_006720374.1

    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  25. XM_011537344.3XP_011535646.1  WD repeat-containing protein 20 isoform X10

    Conserved Domains (3) summary
    COG2319
    Location:97339
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:103168
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:99264
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  26. XM_011537346.1XP_011535648.1  WD repeat-containing protein 20 isoform X13

    See identical proteins and their annotated locations for XP_011535648.1

    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  27. XM_006720310.1XP_006720373.1  WD repeat-containing protein 20 isoform X13

    See identical proteins and their annotated locations for XP_006720373.1

    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  28. XM_011537347.1XP_011535649.1  WD repeat-containing protein 20 isoform X13

    See identical proteins and their annotated locations for XP_011535649.1

    Conserved Domains (2) summary
    sd00039
    Location:5086
    7WD40; WD40 repeat [structural motif]
    cl25539
    Location:29141
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RNA

  1. XR_001750596.2 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_181302.1: Suppressed sequence

    Description
    NM_181302.1: This RefSeq was permanently suppressed because currently there is insufficient support for the protein.
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