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PSTPIP2 proline-serine-threonine phosphatase interacting protein 2 [ Homo sapiens (human) ]

Gene ID: 9050, updated on 13-Mar-2020

Summary

Official Symbol
PSTPIP2provided by HGNC
Official Full Name
proline-serine-threonine phosphatase interacting protein 2provided by HGNC
Primary source
HGNC:HGNC:9581
See related
Ensembl:ENSG00000152229 MIM:616046
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MAYP
Expression
Broad expression in bone marrow (RPKM 28.6), spleen (RPKM 27.4) and 17 other tissues See more
Orthologs

Genomic context

See PSTPIP2 in Genome Data Viewer
Location:
18q21.1; tdb7990
Exon count:
16
Annotation release Status Assembly Chr Location
109.20200228 current GRCh38.p13 (GCF_000001405.39) 18 NC_000018.10 (45983536..46072327, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 18 NC_000018.9 (43563502..43652250, complement)

Chromosome 18 - NC_000018.10Genomic Context describing neighboring genes Neighboring gene ectopic P-granules autophagy protein 5 homolog Neighboring gene sialic acid binding Ig like lectin 15 Neighboring gene Sharpr-MPRA regulatory region 10800 Neighboring gene RN7SK pseudogene 26 Neighboring gene UTP18, small subunit (SSU) processome component, homolog (yeast) pseudogene Neighboring gene tRNA-Lys (CTT) 6-1 Neighboring gene RNY4 pseudogene 37 Neighboring gene ATP synthase F1 subunit alpha

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC34175

Gene Ontology Provided by GOA

Function Evidence Code Pubs
actin binding IEA
Inferred from Electronic Annotation
more info
 
cytoskeletal protein binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
cell migration IEA
Inferred from Electronic Annotation
more info
 
cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
proline-serine-threonine phosphatase-interacting protein 2
Names
PEST phosphatase-interacting protein 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024430.4NP_077748.3  proline-serine-threonine phosphatase-interacting protein 2

    See identical proteins and their annotated locations for NP_077748.3

    Status: VALIDATED

    Source sequence(s)
    AC090355, BC035395, BP352927, DA943980
    Consensus CDS
    CCDS32820.2
    UniProtKB/Swiss-Prot
    Q9H939
    UniProtKB/TrEMBL
    A0A0S2Z4R2
    Related
    ENSP00000387261.4, ENST00000409746.5
    Conserved Domains (1) summary
    cd07672
    Location:15254
    F-BAR_PSTPIP2; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Proline-Serine-Threonine Phosphatase-Interacting Protein 2

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000018.10 Reference GRCh38.p13 Primary Assembly

    Range
    45983536..46072327 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011526253.2XP_011524555.1  proline-serine-threonine phosphatase-interacting protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011524555.1

    UniProtKB/TrEMBL
    A0A0S2Z505
    Conserved Domains (1) summary
    cl12013
    Location:15228
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
  2. XM_011526254.2XP_011524556.1  proline-serine-threonine phosphatase-interacting protein 2 isoform X2

    Conserved Domains (1) summary
    cl12013
    Location:15217
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature
  3. XM_011526256.1XP_011524558.1  proline-serine-threonine phosphatase-interacting protein 2 isoform X3

    See identical proteins and their annotated locations for XP_011524558.1

    Conserved Domains (1) summary
    cl12013
    Location:20202
    BAR; The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature

RNA

  1. XR_935264.2 RNA Sequence

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