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FBF1 Fas binding factor 1 [ Homo sapiens (human) ]

Gene ID: 85302, updated on 24-Nov-2020

Summary

Official Symbol
FBF1provided by HGNC
Official Full Name
Fas binding factor 1provided by HGNC
Primary source
HGNC:HGNC:24674
See related
Ensembl:ENSG00000188878 MIM:616807
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
Alb; FBF-1
Expression
Broad expression in testis (RPKM 14.5), skin (RPKM 4.2) and 22 other tissues See more
Orthologs

Genomic context

See FBF1 in Genome Data Viewer
Location:
17q25.1
Exon count:
29
Annotation release Status Assembly Chr Location
109.20201120 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (75909574..75938232, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (73905925..73937119, complement)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 65 Neighboring gene mitochondrial ribosomal protein L38 Neighboring gene Sharpr-MPRA regulatory region 10813 Neighboring gene acyl-CoA oxidase 1 Neighboring gene TEN1-CDK3 readthrough (NMD candidate) Neighboring gene TEN1 subunit of CST complex

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: MRPL38

Homology

Clone Names

  • FLJ00103, FLJ13996, KIAA1863

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
apical junction assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
ciliary basal body-plasma membrane docking TAS
Traceable Author Statement
more info
 
cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cilium assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
establishment of epithelial cell polarity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
colocalizes_with apical junction complex IDA
Inferred from Direct Assay
more info
PubMed 
centriole IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
centriole IDA
Inferred from Direct Assay
more info
PubMed 
centrosome IDA
Inferred from Direct Assay
more info
 
ciliary basal body IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ciliary transition fiber IDA
Inferred from Direct Assay
more info
PubMed 
cytosol TAS
Traceable Author Statement
more info
 
colocalizes_with keratin filament IDA
Inferred from Direct Assay
more info
PubMed 
spindle pole IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
fas-binding factor 1
Names
Fas (TNFRSF6) binding factor 1
Fas binding protein 1
albatross
protein albatross

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001319193.1NP_001306122.1  fas-binding factor 1

    Status: VALIDATED

    Source sequence(s)
    AB354594, AC087289, AK057261, AK074045, BC007570
    Consensus CDS
    CCDS45779.2
    UniProtKB/Swiss-Prot
    Q8TES7
    Related
    ENSP00000490726.1, ENST00000636174.1
    Conserved Domains (2) summary
    pfam08286
    Location:932987
    Spc24; Spc24 subunit of Ndc80
    pfam14988
    Location:787976
    DUF4515; Domain of unknown function (DUF4515)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20201120

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

    Range
    75909574..75938232 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001080542.1: Suppressed sequence

    Description
    NM_001080542.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.
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